Detailed information NTG0456517

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: HUW56_RS10140
• Genome accession: NZ_CP055160
• Coordinates: 2138164..2139327 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain WLYS23
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2133164..2144327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUW56_RS10110 (HUW56_10110)	-	2133428..2133847 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
HUW56_RS10115 (HUW56_10115)	comFC	2133921..2134610 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
HUW56_RS10120 (HUW56_10120)	-	2134616..2134900 (-)	285	WP_003151389.1	competence protein ComFB	-
HUW56_RS10125 (HUW56_10125)	comFA	2134958..2136343 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
HUW56_RS10130 (HUW56_10130)	-	2136452..2137300 (-)	849	WP_032876160.1	DegV family protein	-
HUW56_RS10135 (HUW56_10135)	degU	2137398..2138087 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
HUW56_RS10140 (HUW56_10140)	degS	2138164..2139327 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
HUW56_RS10145 (HUW56_10145)	-	2139550..2140197 (+)	648	WP_007614107.1	YigZ family protein	-
HUW56_RS10150 (HUW56_10150)	-	2140202..2141383 (+)	1182	WP_032876157.1	LCP family protein	-
HUW56_RS10155 (HUW56_10155)	-	2141482..2142558 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
HUW56_RS10160 (HUW56_10160)	-	2142691..2143887 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=456517 HUW56_RS10140 WP_007407484.1 2138164..2139327(-) (degS) [Bacillus velezensis strain WLYS23]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=456517 HUW56_RS10140 WP_007407484.1 2138164..2139327(-) (degS) [Bacillus velezensis strain WLYS23]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951