Detailed information NTG0455237

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HUW54_RS13430
• Genome accession: NZ_CP054876
• Coordinates: 2687876..2688763 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain Dresden-275757
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2682876..2693763

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUW54_RS13400 (HUW54_13400)	-	2682894..2682986 (+)	93	WP_010956583.1	hypothetical protein	-
HUW54_RS13405 (HUW54_13405)	-	2683094..2683591 (-)	498	WP_001065268.1	glutathione peroxidase	-
HUW54_RS13410 (HUW54_13410)	-	2683601..2683861 (-)	261	WP_001791974.1	hypothetical protein	-
HUW54_RS13415 (HUW54_13415)	-	2684243..2684356 (-)	114	Protein_2611	hypothetical protein	-
HUW54_RS13420 (HUW54_13420)	-	2685015..2687015 (-)	2001	WP_000776751.1	ABC transporter permease	-
HUW54_RS13425 (HUW54_13425)	-	2687012..2687767 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HUW54_RS13430 (HUW54_13430)	braS	2687876..2688763 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HUW54_RS13435 (HUW54_13435)	braR	2688774..2689439 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HUW54_RS13440 (HUW54_13440)	-	2689465..2689665 (-)	201	WP_000604727.1	hypothetical protein	-
HUW54_RS13445 (HUW54_13445)	-	2689863..2691287 (+)	1425	WP_000953757.1	alkaline phosphatase	-
HUW54_RS13450 (HUW54_13450)	-	2691357..2691467 (+)	111	WP_001791296.1	hypothetical protein	-
HUW54_RS13455 (HUW54_13455)	-	2691570..2692025 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HUW54_RS13460 (HUW54_13460)	-	2692270..2693031 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=455237 HUW54_RS13430 WP_000143420.1 2687876..2688763(-) (braS) [Staphylococcus aureus strain Dresden-275757]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=455237 HUW54_RS13430 WP_000143420.1 2687876..2688763(-) (braS) [Staphylococcus aureus strain Dresden-275757]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993