Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   HUW54_RS00175 Genome accession   NZ_CP054876
Coordinates   43985..45334 (-) Length   449 a.a.
NCBI ID   WP_175528685.1    Uniprot ID   -
Organism   Staphylococcus aureus strain Dresden-275757     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 38985..50334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUW54_RS00145 (HUW54_00145) - 39143..40273 (+) 1131 WP_197945456.1 GIY-YIG nuclease family protein -
  HUW54_RS00150 (HUW54_00150) - 40367..40588 (-) 222 WP_175528681.1 hypothetical protein -
  HUW54_RS00155 (HUW54_00155) - 40603..41105 (-) 503 Protein_28 DUF1643 domain-containing protein -
  HUW54_RS00160 (HUW54_00160) - 41121..41432 (-) 312 WP_175528682.1 DUF960 family protein -
  HUW54_RS00165 (HUW54_00165) - 41519..41869 (-) 351 WP_175528683.1 SAUGI family uracil-DNA glycosylase inhibitor -
  HUW54_RS00170 (HUW54_00170) ccrB 42336..43964 (-) 1629 WP_175528684.1 recombinase family protein Machinery gene
  HUW54_RS00175 (HUW54_00175) ccrA 43985..45334 (-) 1350 WP_175528685.1 recombinase family protein Machinery gene
  HUW54_RS00180 (HUW54_00180) - 45525..45800 (-) 276 WP_044466491.1 hypothetical protein -
  HUW54_RS00185 (HUW54_00185) - 45869..47656 (-) 1788 WP_175528686.1 DUF927 domain-containing protein -
  HUW54_RS00190 (HUW54_00190) - 47656..47925 (-) 270 WP_000875688.1 hypothetical protein -
  HUW54_RS00195 (HUW54_00195) - 48080..49639 (-) 1560 WP_175528687.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52489.10 Da        Isoelectric Point: 10.0411

>NTDB_id=455198 HUW54_RS00175 WP_175528685.1 43985..45334(-) (ccrA) [Staphylococcus aureus strain Dresden-275757]
MKQAIGYLRQSTTKQQSLAAQKQTIEALAKKHNITYITFYSDKQSGRTDKRNGYQQITELIQQGQCNVLCCYRLNRLHRN
LKNALKLMKLCQKYHIHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKARQGKLITTHAPFGYHYH
NGTFTIDTVKSPTVKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPNHSLRYYVCPKNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDIETKTTLNHEQLIEKLAQGKIDADTFREQSQSFRQQSNPITSINAHQIRKVFQ
NIIQQRFTLNMLYPYIDEIHITKNKTLTGIYFKNEPLNIVNQTAQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=455198 HUW54_RS00175 WP_175528685.1 43985..45334(-) (ccrA) [Staphylococcus aureus strain Dresden-275757]
ATGAAACAAGCAATAGGTTACTTACGACAGAGCACTACAAAGCAACAATCCCTAGCAGCACAAAAACAAACCATAGAGGC
ATTAGCCAAAAAACATAATATTACATACATTACCTTTTATAGCGATAAGCAATCAGGACGTACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAAGGACAATGTAACGTATTATGTTGTTACAGATTAAACCGACTTCATCGCAAT
CTTAAAAATGCATTAAAACTCATGAAATTGTGTCAAAAATACCATATCCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAGACAAGGTAAACTAATTACAACACATGCACCCTTTGGGTATCACTATCAT
AATGGTACTTTCACAATAGACACAGTAAAATCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATCCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTCAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGCCATTCGACACTCACAAACATGACCGTCCGAAAACCAAATCATTCATTGCGTTACTATGTCTGTCCGA
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAATCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TATAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGATACGTTCA
GAGAACAATCGCAATCATTTCGACAACAGTCAAACCCTATAACATCAATCAATGCACATCAAATTCGAAAGGTTTTTCAA
AATATCATACAACAACGTTTCACGTTAAACATGTTGTACCCTTACATTGATGAAATTCATATTACCAAAAATAAAACACT
TACGGGTATCTATTTCAAAAATGAGCCCTTAAACATCGTCAATCAAACGGCGCAATCATCGATTGCTTAA

Domains

Predicted by InterProScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Recombinase (Recombinase)

(170-249)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

92.428

100

0.924
  ccrA Staphylococcus aureus N315

75.724

100

0.757