Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   JF649_RS04015 Genome accession   NZ_CP066541
Coordinates   787990..788466 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain MGAS270     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 782990..793466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JF649_RS03985 (JF649_03970) - 783639..784067 (+) 429 WP_023079239.1 DUF1617 family protein -
  JF649_RS03990 (JF649_03975) - 784070..784681 (+) 612 WP_023079230.1 DUF1366 domain-containing protein -
  JF649_RS03995 (JF649_03980) - 784691..785146 (+) 456 WP_002986151.1 phage holin family protein -
  JF649_RS04000 (JF649_03985) - 785264..786016 (+) 753 WP_002993615.1 CHAP domain-containing protein -
  JF649_RS04005 (JF649_03990) - 786182..786469 (+) 288 WP_023079212.1 hypothetical protein -
  JF649_RS04010 (JF649_03995) speh 786675..787385 (+) 711 WP_012560660.1 streptococcal pyrogenic exotoxin SpeH -
  JF649_RS04015 (JF649_04000) mutX 787990..788466 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  JF649_RS04020 (JF649_04005) - 788524..789705 (+) 1182 WP_038432925.1 AI-2E family transporter -
  JF649_RS04025 (JF649_04010) - 789695..790942 (+) 1248 WP_030125976.1 tetratricopeptide repeat protein -
  JF649_RS04030 (JF649_04015) fbp54 791002..792654 (-) 1653 WP_030125975.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=455169 JF649_RS04015 WP_002984880.1 787990..788466(+) (mutX) [Streptococcus pyogenes strain MGAS270]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=455169 JF649_RS04015 WP_002984880.1 787990..788466(+) (mutX) [Streptococcus pyogenes strain MGAS270]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703