Detailed information NTG0045483

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: A7A1_RS20235
• Genome accession: NC_019896
• Coordinates: 3935336..3936418 (-)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis subsp. subtilis str. BSP1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3930336..3941418

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7A1_RS20205 (A7A1_0113)	cysE	3930440..3931093 (-)	654	WP_003225749.1	serine O-acetyltransferase	-
A7A1_RS20215 (A7A1_0114)	gltX	3931396..3932847 (-)	1452	WP_004399675.1	glutamate--tRNA ligase	-
A7A1_RS20220 (A7A1_0115)	ispF	3932938..3933414 (-)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
A7A1_RS20225 (A7A1_0116)	ispD	3933407..3934105 (-)	699	WP_015252991.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
A7A1_RS20230 (A7A1_0117)	yacL	3934120..3935220 (-)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
A7A1_RS20235 (A7A1_0118)	disA	3935336..3936418 (-)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
A7A1_RS20240 (A7A1_0119)	radA/sms	3936422..3937798 (-)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
A7A1_RS20245 (A7A1_0120)	clpC	3937890..3940322 (-)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
A7A1_RS20250 (A7A1_0121)	mcsB	3940319..3941410 (-)	1092	WP_003235007.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=45483 A7A1_RS20235 WP_003225736.1 3935336..3936418(-) (disA) [Bacillus subtilis subsp. subtilis str. BSP1]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=45483 A7A1_RS20235 WP_003225736.1 3935336..3936418(-) (disA) [Bacillus subtilis subsp. subtilis str. BSP1]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCCATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1