Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   HSZ48_RS04875 Genome accession   NZ_CP054831
Coordinates   1004000..1005043 (+) Length   347 a.a.
NCBI ID   WP_011302781.1    Uniprot ID   -
Organism   Staphylococcus saprophyticus strain UTI-045     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 999000..1010043
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSZ48_RS04840 (HSZ48_04855) - 999397..999612 (+) 216 WP_103301910.1 helix-turn-helix domain-containing protein -
  HSZ48_RS04845 (HSZ48_04860) - 999630..999935 (+) 306 WP_011302776.1 helix-turn-helix domain-containing protein -
  HSZ48_RS04850 (HSZ48_04865) - 999941..1000804 (+) 864 WP_075345165.1 IS3 family transposase -
  HSZ48_RS04855 (HSZ48_04870) - 1000882..1001868 (-) 987 WP_002482841.1 aromatic acid exporter family protein -
  HSZ48_RS04860 (HSZ48_04875) map 1002043..1002795 (+) 753 WP_011302778.1 type I methionyl aminopeptidase -
  HSZ48_RS04865 (HSZ48_04880) - 1002899..1003285 (+) 387 WP_011302779.1 hypothetical protein -
  HSZ48_RS04870 (HSZ48_04885) liaF 1003302..1004003 (+) 702 WP_011302780.1 cell wall-active antibiotics response protein LiaF -
  HSZ48_RS04875 (HSZ48_04890) vraS 1004000..1005043 (+) 1044 WP_011302781.1 sensor histidine kinase Regulator
  HSZ48_RS04880 (HSZ48_04895) vraR 1005033..1005662 (+) 630 WP_002482846.1 response regulator transcription factor Regulator
  HSZ48_RS04885 (HSZ48_04900) - 1005819..1006991 (-) 1173 WP_011302782.1 YihY/virulence factor BrkB family protein -
  HSZ48_RS04890 (HSZ48_04905) - 1007403..1007687 (-) 285 WP_002482848.1 hypothetical protein -
  HSZ48_RS04895 (HSZ48_04910) - 1007694..1008158 (-) 465 WP_011302783.1 low molecular weight protein-tyrosine-phosphatase -
  HSZ48_RS04900 (HSZ48_04915) - 1008293..1008496 (+) 204 WP_002482850.1 DUF1128 family protein -
  HSZ48_RS04905 (HSZ48_04920) - 1008510..1009748 (+) 1239 WP_011302784.1 aminopeptidase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40050.55 Da        Isoelectric Point: 6.4221

>NTDB_id=454784 HSZ48_RS04875 WP_011302781.1 1004000..1005043(+) (vraS) [Staphylococcus saprophyticus strain UTI-045]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSNAD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=454784 HSZ48_RS04875 WP_011302781.1 1004000..1005043(+) (vraS) [Staphylococcus saprophyticus strain UTI-045]
ATGAATCACTACTTTAGAGCGATCGGGTCCATGTTGATATTAGTATATAGTACGTTTTTTGCCATATTCTTTATTGATAA
AGTGTTTGTTAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCTGTACTGCTTTTTTTAAATC
TAATGGTGATTTTACTCTGTATTATTGTAGGTTCTGTCTTAGCATATAAAATCAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAACGTTCAATAGAAGGTCAAACAGTGGGTATCAATGATCAAAATATTGAATTATACAACGAAACAATCGAACT
ATATCAAACGCTTGTGCCTTTAAATCAAGAAGTACATAAATTAAGAATGAAAACACAGAACCTGACGAATGAATCTTATA
ATATCAATGATGTTAAAGTTAAGAAAATTATAGAAGACGAACGCCAACGTTTAGCGCGTGAATTACATGATTCAGTTAGT
CAACAATTATTCGCAGCAAGTATGATGTTATCAGCAATTAAAGAGACAGAATTGAAGGCCCCATTGGACCAACAAATACC
AGTATTAGAAAAAATGATTCAAGATTCCCAATTAGAAATGAGAGCACTACTATTACACTTAAGACCTATTGGTTTGAAAG
ATAAATCTTTAGGTGAGGGTATTAAAGATTTAGTCGTTGATTTACAGAAAAAAGTACCAATGAAAGTGGTACATGATATT
GAAGAATTCAAAGTACCAAAAGGTATCGAGGACCATTTATTCCGTATTACGCAAGAAGCCATTTCTAATACGCTAAGACA
TTCTAAAGGAACGAAGGTCACAATTGAATTATTTAATAGGGAAGAATATTTGTTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGCGAACGTGCACTAGAAATAGGTGCAACA
TTTCATATCGTTTCTTTGCCTGATGCAGGTACGAGAATTGAAGTAAAGGCACCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(147-210)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

87.32

100

0.873