Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   JDY60_RS00245 Genome accession   NZ_CP066172
Coordinates   57862..59967 (+) Length   701 a.a.
NCBI ID   WP_001063369.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 52862..64967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS00240 (JDY60_00240) - 53326..57408 (+) 4083 WP_200370855.1 Spy0128 family protein -
  JDY60_RS00245 (JDY60_00245) clpE 57862..59967 (+) 2106 WP_001063369.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  JDY60_RS00250 (JDY60_00250) - 60028..60510 (-) 483 WP_000032557.1 S-ribosylhomocysteine lyase -
  JDY60_RS00255 (JDY60_00255) - 60605..62089 (-) 1485 WP_200370856.1 DUF1846 domain-containing protein -
  JDY60_RS00260 (JDY60_00260) - 62242..63852 (+) 1611 WP_200370857.1 alpha-glucosidase -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77546.34 Da        Isoelectric Point: 4.7404

>NTDB_id=453920 JDY60_RS00245 WP_001063369.1 57862..59967(+) (clpE) [Streptococcus oralis strain SF100]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAESDVQMQQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSIGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSIQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNAKTRIAELEKKVENHTEDMKVTASINDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLEHKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLNKEDLSKIVDLMLAEVNQTLAKKDIDLEVS
QAAKDFITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=453920 JDY60_RS00245 WP_001063369.1 57862..59967(+) (clpE) [Streptococcus oralis strain SF100]
ATGAACAACAACTTTAATAACTTTAACAACATGGATGATTTATTTAACCAATTGATGGGAGGTATGCGAGGATATAGTTC
TGAAAATCGTCGCTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAATCTGATGTGCAAATGCAACAACAGGCTTCAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGT
CGTAACTTGACCGCAGAAGCTCGTGAGGGCAAGCTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGTCGTACGAAAAATAATCCTGTTCTAGTCGGAGATGCAGGTGTTGGAAAGACAGCCGTTGTCGAAGGTC
TAGCACAAGCGATTGTGAATGGAGATGTTCCGGCTGCCATCAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAACGTTCAAAATCTAGTCAATGAAGTAAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATCCTTGGCGCTGGCTCAATCGGAGGAGACAGTGGTTCTAAAGGGCTTGCGG
ACATTCTCAAGCCAGCTCTCTCTCGTGGTGAATTGACCGTTATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAAAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTCAAGGTCAATGCTCCTTCAGCAGAGGATACCTTTAAAATCCT
TCAAGGGATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCAGTGGATTATT
CTATCCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTAGACGTAACGGCTGCTCACTTGGCAGCT
CAACATCCTGTAACAGATGTGCATGCTGTTGAACGGGAAATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGACTTTGAAGCAGCTCTCAATGCCAAGACGCGTATTGCTGAATTGGAGAAAAAAGTCGAAAACCACACAGAAGACA
TGAAAGTGACTGCAAGCATCAACGATGTGGCTGAGTCTGTAGAGCGAATGACAGGTATTCCAGTGTCACAAATGGGAGCA
TCCGACATCGAACGCCTCAAGGATATGGCTCATCGTTTGGAACACAAGGTTATCGGCCAAGACAAGGCAGTTGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGCAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGTCCAA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCGCTCGATATGTTTGGAACCAAGGATGCGATCATTCGCTTGGAT
ATGTCTGAATACAGTGACCGCACAGCCGTATCTAAATTGATCGGTACAACAGCCGGTTATGTGGGTTATGATGACAATAG
CAATACCTTGACAGAACGTGTTCGTCGTAATCCTTACTCTATCATTCTCTTGGACGAAATTGAAAAGGCTGATCCTCAAG
TCATTACCCTTCTCCTCCAAGTCTTGGATGATGGTCGTTTGACTGATGGTCAAGGAAATACAGTGAACTTCAAGAACACA
GTCATTATCGCGACATCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAGCCAGAATTGATGGA
TCGTTTGAAACCATTCTTCCGCCCAGAGTTCCTTAACCGCTTTAACGCAGTTATCGAATTCTCACACTTGAATAAGGAAG
ACCTTTCTAAGATTGTGGACTTGATGTTGGCGGAAGTCAACCAAACCTTGGCTAAGAAAGACATTGATTTGGAAGTCAGC
CAAGCAGCTAAAGACTTTATCACAGAAGAAGGTTATGACGAAGTTATGGGTGTTCGCCCTCTCCGTCGCGTGGTGGAACA
ACAAATTCGTGATAAGGTAACAGATTTCCACTTGGATCATCTAGATGCCAAACATTTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAAAAAGCCTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(259-354)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-603)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

50.776

91.869

0.466
  clpC Lactococcus lactis subsp. cremoris KW2

50.156

91.298

0.458
  clpE Streptococcus pneumoniae Rx1

48.976

90.585

0.444
  clpE Streptococcus pneumoniae D39

48.976

90.585

0.444
  clpE Streptococcus pneumoniae R6

48.976

90.585

0.444
  clpE Streptococcus pneumoniae TIGR4

48.896

90.442

0.442
  clpC Bacillus subtilis subsp. subtilis str. 168

45.146

92.582

0.418
  clpC Streptococcus pneumoniae D39

43.109

89.016

0.384
  clpC Streptococcus pneumoniae Rx1

43.109

89.016

0.384
  clpC Streptococcus pneumoniae TIGR4

42.949

89.016

0.382
  clpC Streptococcus thermophilus LMD-9

43.112

88.017

0.379
  clpC Streptococcus thermophilus LMG 18311

42.95

88.017

0.378
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.788

88.017

0.377
  clpC Streptococcus mutans UA159

42.071

88.16

0.371