Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   FOB47_RS15410 Genome accession   NZ_CP054626
Coordinates   1134439..1136952 (+) Length   837 a.a.
NCBI ID   WP_174781470.1    Uniprot ID   -
Organism   Cupriavidus gilardii strain FDAARGOS_639     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1112433..1136952 1134439..1136952 within 0


Gene organization within MGE regions


Location: 1112433..1136952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB47_RS15310 (FOB47_15310) uvrB 1112433..1114529 (+) 2097 WP_174781462.1 excinuclease ABC subunit UvrB -
  FOB47_RS15315 (FOB47_15315) - 1114695..1115171 (+) 477 WP_053821499.1 low molecular weight protein-tyrosine-phosphatase -
  FOB47_RS15320 (FOB47_15320) - 1115263..1117458 (+) 2196 WP_174781463.1 site-specific recombinase -
  FOB47_RS15325 (FOB47_15325) iscR 1117594..1118160 (+) 567 WP_053821501.1 Fe-S cluster assembly transcriptional regulator IscR -
  FOB47_RS15330 (FOB47_15330) - 1118225..1119442 (+) 1218 WP_174781464.1 IscS subfamily cysteine desulfurase -
  FOB47_RS15335 (FOB47_15335) iscU 1119490..1119894 (+) 405 WP_053821503.1 Fe-S cluster assembly scaffold IscU -
  FOB47_RS15340 (FOB47_15340) iscA 1119918..1120238 (+) 321 WP_023263777.1 iron-sulfur cluster assembly protein IscA -
  FOB47_RS15345 (FOB47_15345) hscB 1120356..1120874 (+) 519 WP_053821504.1 Fe-S protein assembly co-chaperone HscB -
  FOB47_RS15350 (FOB47_15350) hscA 1120997..1122862 (+) 1866 WP_174781465.1 Fe-S protein assembly chaperone HscA -
  FOB47_RS15355 (FOB47_15355) fdx 1122908..1123246 (+) 339 WP_053821506.1 ISC system 2Fe-2S type ferredoxin -
  FOB47_RS15360 (FOB47_15360) iscX 1123314..1123508 (+) 195 WP_006577719.1 Fe-S cluster assembly protein IscX -
  FOB47_RS15365 (FOB47_15365) lysS 1123576..1125108 (-) 1533 WP_174781466.1 lysine--tRNA ligase -
  FOB47_RS15370 (FOB47_15370) - 1125150..1125932 (-) 783 WP_174781467.1 SDR family oxidoreductase -
  FOB47_RS15380 (FOB47_15380) - 1127449..1128195 (+) 747 WP_151023243.1 M23 family metallopeptidase -
  FOB47_RS15385 (FOB47_15385) recJ 1128306..1130003 (-) 1698 WP_174781468.1 single-stranded-DNA-specific exonuclease RecJ -
  FOB47_RS15390 (FOB47_15390) - 1130095..1131246 (-) 1152 WP_174781469.1 hypothetical protein -
  FOB47_RS15395 (FOB47_15395) - 1131387..1132637 (+) 1251 WP_053821509.1 lipoprotein-releasing ABC transporter permease subunit -
  FOB47_RS15400 (FOB47_15400) lolD 1132630..1133388 (+) 759 WP_053821510.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  FOB47_RS15405 (FOB47_15405) - 1133416..1134258 (+) 843 WP_053821511.1 TatD family hydrolase -
  FOB47_RS15410 (FOB47_15410) comA 1134439..1136952 (+) 2514 WP_174781470.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 837 a.a.        Molecular weight: 89007.80 Da        Isoelectric Point: 11.6881

>NTDB_id=453872 FOB47_RS15410 WP_174781470.1 1134439..1136952(+) (comA) [Cupriavidus gilardii strain FDAARGOS_639]
MRLTLCAFVAGCWLVQQLPALPPASIGVTAGLAALVVVIALSPLAGRPGPSSIGLHVRLLATVLAALIVGAAWSVWRAER
RLAERLAAQFEGVTLSLTGVVSGLPTGNGEGLRFAFTVDGDRPAGLPPLLSLGWQQAPPDLLPGTRLAVTARLKRPHGLA
NPHGFDYEYWLLQRGIGATGYVLAARPAAPVALRPAWRIARWRAQIRSRMLAAMPAEAPLAGVLVALAIGDQSGIAAEQW
RWFTRTGIGHLVSISGLHITMISGLAGALARALWRRSFGVGRWLRRPLPLRCPAQRAAALVAVAMALGYGLLSGMEVPAQ
RTVAMVSVAALALWWQRRPPASLVLAWAAAVALALDPWAVRAAGFWLSFGAVAAIFVAASQRTVAVTGGEPSQRSVWQAR
WQGVRRHLAESVRTQWAVTIGLLPPTLLLFQQVSVVSPLANALAIPLVSLLVTPLALCAALLAAWPVDWPAGGAIAMAAA
SLLALAHQAMAWLAAALVRLAALDWAVWQAARPDTVELAFALLGTAVLLAPRAFGWGWRVHGLVLLIPMLSSGRAPLPAA
AFRATALDVGQGAAVLIETRGHRLLYDAGPAYGPADAPRPSAGERVVVPFLRAVGIHSLDALVISHEDADHAGGARDVMA
ALPVRRLWGSLPRGHPLWRWPPGGGPDVGQVCAAGIAWQWDGVRFELLHPLPGQGDDAAIGSNARSCVLRVSSPYAAMLL
TGDIDRAAELAMVARLPPDALRADLLLVPHHGSRTSSSDEWLDAVRPAAAVFQLGYRNRYRHPHAQVWARYGRRGIARYR
SDRTGAVEVVADRDGIAIASFRQQARRYWRPAPDAPE

Nucleotide


Download         Length: 2514 bp        

>NTDB_id=453872 FOB47_RS15410 WP_174781470.1 1134439..1136952(+) (comA) [Cupriavidus gilardii strain FDAARGOS_639]
ATGCGCCTGACGCTGTGCGCCTTCGTCGCGGGCTGCTGGCTGGTGCAGCAATTGCCGGCATTGCCGCCAGCGTCGATCGG
CGTGACCGCCGGTCTGGCCGCATTGGTCGTGGTGATCGCGCTGTCGCCGCTTGCCGGGCGTCCGGGGCCTTCCTCGATCG
GCCTCCATGTGCGCTTGCTGGCCACCGTGCTGGCCGCGCTGATCGTCGGCGCGGCATGGTCCGTCTGGCGTGCCGAGCGT
CGCCTGGCCGAGCGGCTTGCGGCGCAGTTCGAAGGCGTCACGCTGTCGCTGACGGGCGTGGTGTCGGGACTGCCGACGGG
CAACGGCGAGGGCCTGCGTTTCGCGTTCACGGTCGACGGCGACAGGCCGGCCGGCTTGCCGCCGCTGCTGTCGCTCGGCT
GGCAGCAGGCGCCGCCCGATCTGCTGCCCGGCACGCGGCTGGCGGTGACCGCACGGCTGAAGCGGCCACATGGTCTCGCC
AATCCGCATGGCTTCGACTACGAATACTGGCTGCTGCAGCGGGGCATTGGCGCAACCGGCTACGTGCTGGCGGCCCGCCC
CGCAGCGCCGGTGGCCCTGCGGCCGGCCTGGCGCATTGCCCGCTGGCGTGCGCAGATCCGGTCCCGCATGCTGGCGGCGA
TGCCGGCCGAGGCGCCGTTGGCGGGCGTGCTGGTGGCGCTGGCGATCGGCGACCAGAGCGGCATCGCCGCCGAGCAGTGG
CGCTGGTTCACGCGCACCGGCATCGGCCATCTGGTCAGCATCTCGGGCCTGCATATCACGATGATCTCGGGGCTGGCGGG
CGCGCTGGCACGGGCCCTGTGGCGGCGCTCGTTCGGCGTGGGCAGATGGCTGCGGCGGCCGCTGCCGTTGCGTTGTCCGG
CGCAGCGGGCGGCGGCGCTGGTCGCCGTGGCGATGGCGCTCGGCTATGGGCTGCTGTCGGGTATGGAGGTGCCGGCGCAA
CGCACGGTGGCGATGGTATCCGTGGCCGCGCTGGCGCTGTGGTGGCAGCGCCGGCCGCCGGCCTCGCTGGTGCTGGCCTG
GGCCGCCGCGGTCGCGCTGGCGCTCGACCCGTGGGCGGTGCGGGCGGCGGGCTTCTGGCTGTCGTTCGGCGCGGTCGCCG
CGATCTTCGTGGCGGCGTCGCAGCGAACCGTGGCCGTGACCGGCGGCGAGCCGTCGCAGCGTTCGGTCTGGCAGGCGCGC
TGGCAAGGCGTGCGGCGGCACCTGGCCGAGTCGGTGCGCACGCAATGGGCCGTCACGATCGGACTGCTGCCGCCGACGCT
GCTGTTGTTCCAGCAGGTGTCGGTGGTGTCGCCGCTGGCCAATGCGCTGGCGATTCCGCTCGTCAGCCTGCTGGTGACGC
CGCTGGCGTTGTGCGCGGCGCTGCTGGCCGCCTGGCCCGTGGACTGGCCGGCAGGCGGCGCCATCGCGATGGCGGCCGCA
TCGCTGCTGGCGCTGGCGCACCAGGCGATGGCATGGCTGGCGGCGGCGCTGGTGCGGCTGGCGGCGCTGGACTGGGCCGT
CTGGCAGGCGGCGCGGCCGGACACGGTCGAGCTCGCCTTCGCGCTGCTCGGCACGGCGGTGCTGCTGGCCCCGCGCGCCT
TCGGCTGGGGCTGGCGCGTGCACGGCCTGGTGCTGCTGATCCCGATGCTGTCGAGCGGCCGCGCGCCGCTGCCGGCCGCG
GCCTTCCGCGCGACGGCGCTCGATGTCGGACAGGGCGCCGCGGTGCTGATCGAGACCCGCGGCCATCGGCTGCTGTACGA
CGCCGGGCCAGCCTATGGCCCCGCCGACGCGCCACGGCCCAGCGCCGGCGAACGCGTGGTGGTGCCGTTCCTGCGCGCGG
TCGGCATCCATTCGCTCGATGCGCTGGTGATCAGCCACGAGGATGCCGATCATGCCGGCGGTGCGCGCGACGTGATGGCC
GCGCTGCCGGTCCGGCGCCTGTGGGGCTCGCTGCCGCGTGGCCATCCGCTATGGCGGTGGCCGCCCGGGGGCGGACCCGA
TGTCGGTCAGGTGTGCGCGGCCGGTATCGCGTGGCAATGGGACGGCGTGCGCTTCGAACTGCTGCATCCGTTGCCGGGGC
AGGGCGACGACGCGGCGATCGGCAGCAATGCGCGCAGCTGCGTGCTGCGGGTCTCGAGTCCTTACGCCGCGATGCTGCTG
ACCGGCGATATCGACCGCGCCGCCGAACTGGCGATGGTGGCGCGCCTGCCGCCCGATGCGCTGCGCGCCGACCTGCTGCT
GGTGCCGCACCATGGCAGCCGCACCTCGTCCAGCGACGAATGGCTCGACGCGGTAAGGCCCGCCGCGGCGGTGTTCCAGC
TCGGCTATCGCAACCGCTACCGGCATCCGCATGCGCAGGTATGGGCGCGCTATGGCCGCCGCGGGATCGCGCGCTATCGC
AGCGATCGCACCGGCGCGGTCGAAGTCGTCGCGGATCGGGACGGCATCGCGATCGCGTCGTTCCGGCAGCAGGCGCGGCG
CTACTGGCGGCCGGCGCCGGATGCGCCGGAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(227-531)

Metallo-beta-lactamase superfamily (Lactamase_B)

(568-771)

Domain of unknown function (DUF4131) (DUF4131)

(20-183)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

48.552

100

0.501