Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   I6I02_RS01390 Genome accession   NZ_CP066093
Coordinates   277690..279795 (+) Length   701 a.a.
NCBI ID   WP_198463663.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 272690..284795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS01360 (I6I02_01360) - 273181..273681 (+) 501 WP_198463660.1 cysteine hydrolase family protein -
  I6I02_RS01365 (I6I02_01365) rsfS 273696..274046 (+) 351 WP_002891669.1 ribosome silencing factor -
  I6I02_RS01370 (I6I02_01370) - 274489..275229 (+) 741 WP_004183284.1 class I SAM-dependent DNA methyltransferase -
  I6I02_RS01375 (I6I02_01375) - 275236..276327 (+) 1092 WP_198463661.1 nucleotidyltransferase -
  I6I02_RS01380 (I6I02_01380) - 276469..276723 (+) 255 WP_060971904.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  I6I02_RS01385 (I6I02_01385) - 276727..276981 (+) 255 WP_198463662.1 Txe/YoeB family addiction module toxin -
  I6I02_RS01390 (I6I02_01390) clpE 277690..279795 (+) 2106 WP_198463663.1 AAA family ATPase Regulator
  I6I02_RS01395 (I6I02_01395) tnpA 279992..280465 (+) 474 WP_002891962.1 IS200/IS605 family transposase -
  I6I02_RS01400 (I6I02_01400) - 280681..281646 (-) 966 WP_002890057.1 IS3 family transposase -
  I6I02_RS01405 (I6I02_01405) - 281643..282320 (-) 678 WP_002890056.1 helix-turn-helix domain-containing protein -
  I6I02_RS11070 - 282765..282890 (+) 126 WP_002884447.1 hypothetical protein -
  I6I02_RS01410 (I6I02_01410) - 282908..283516 (+) 609 WP_002884297.1 DUF4230 domain-containing protein -
  I6I02_RS01415 (I6I02_01415) - 283680..284075 (+) 396 WP_198463664.1 hypothetical protein -
  I6I02_RS01420 (I6I02_01420) - 284093..284260 (+) 168 WP_162837453.1 hypothetical protein -
  I6I02_RS01425 (I6I02_01425) - 284441..284740 (-) 300 WP_195435440.1 hypothetical protein -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77325.20 Da        Isoelectric Point: 4.6947

>NTDB_id=453736 I6I02_RS01390 WP_198463663.1 277690..279795(+) (clpE) [Streptococcus salivarius strain FDAARGOS_1045]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEAEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTEDLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAE

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=453736 I6I02_RS01390 WP_198463663.1 277690..279795(+) (clpE) [Streptococcus salivarius strain FDAARGOS_1045]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCGATTTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACAAAGAATAACCCAGTCCTTGTAGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATTTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCTGCCCTAGCCCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGCTGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGAAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTAGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAAAATACTGTGATT
ATCGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAGCCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGCCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTGAATAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)

AAA lid domain (AAA_lid_9)

(257-352)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

47.361

100

0.474
  clpC Lactococcus lactis subsp. cremoris KW2

49.621

94.009

0.466
  clpE Streptococcus pneumoniae D39

49.224

91.869

0.452
  clpE Streptococcus pneumoniae R6

49.224

91.869

0.452
  clpE Streptococcus pneumoniae Rx1

49.224

91.869

0.452
  clpE Streptococcus pneumoniae TIGR4

48.989

91.726

0.449
  clpC Bacillus subtilis subsp. subtilis str. 168

46.296

92.439

0.428
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.243

92.867

0.392
  clpC Streptococcus pneumoniae TIGR4

44.013

88.16

0.388
  clpC Streptococcus pneumoniae Rx1

44.013

88.16

0.388
  clpC Streptococcus pneumoniae D39

44.013

88.16

0.388
  clpC Streptococcus thermophilus LMD-9

43.274

88.017

0.381
  clpC Streptococcus thermophilus LMG 18311

42.811

88.302

0.378
  clpC Streptococcus mutans UA159

42.308

89.016

0.377