Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6H74_RS04185 Genome accession   NZ_CP066069
Coordinates   837638..838279 (+) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 832638..843279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS04165 (I6H74_04160) - 833194..833934 (+) 741 WP_014612505.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6H74_RS04170 (I6H74_04165) pknB 833931..835826 (+) 1896 WP_003052158.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6H74_RS04175 (I6H74_04170) liaF 835952..836644 (+) 693 WP_015057977.1 cell wall-active antibiotics response protein LiaF -
  I6H74_RS04180 (I6H74_04175) - 836641..837645 (+) 1005 WP_003061197.1 sensor histidine kinase -
  I6H74_RS04185 (I6H74_04180) vraR 837638..838279 (+) 642 WP_014612503.1 response regulator transcription factor Regulator
  I6H74_RS04190 (I6H74_04185) - 838316..839716 (+) 1401 WP_046177466.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6H74_RS04195 (I6H74_04190) - 839716..840075 (+) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  I6H74_RS04200 (I6H74_04195) cysK 840228..841163 (-) 936 WP_003062335.1 cysteine synthase A -
  I6H74_RS04205 (I6H74_04200) - 841267..841905 (-) 639 WP_115256985.1 YigZ family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=453550 I6H74_RS04185 WP_014612503.1 837638..838279(+) (vraR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=453550 I6H74_RS04185 WP_014612503.1 837638..838279(+) (vraR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTGCTGG
TTATGGATTTGGTGATGCCAGAATTAGGTGGGGTTGAGGCGACTTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACCTCTTATTTGGACAATGAGAAAATTTACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAATGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGACCAACACCCGGATTTGCATGAAGAGCTAACCGCGCGCGAGTATGATATTTTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376