Detailed information NTG0453533

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FOC72_RS11210
• Genome accession: NZ_CP054570
• Coordinates: 2296699..2299128 (+)
• Length: 809 a.a.
• NCBI ID: WP_002894011.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain FDAARGOS_770
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2291699..2304128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC72_RS11175 (FOC72_11175)	nusG	2291707..2292243 (+)	537	WP_002894018.1	transcription termination/antitermination protein NusG	-
FOC72_RS11180 (FOC72_11180)	-	2292329..2293093 (-)	765	WP_002894016.1	hypothetical protein	-
FOC72_RS11190 (FOC72_11190)	rpsB	2293601..2294383 (+)	783	WP_002894015.1	30S ribosomal protein S2	-
FOC72_RS11195 (FOC72_11195)	tsf	2294456..2295499 (+)	1044	WP_002894014.1	translation elongation factor Ts	-
FOC72_RS11200 (FOC72_11200)	-	2295599..2296087 (-)	489	WP_002894013.1	hypothetical protein	-
FOC72_RS11205 (FOC72_11205)	-	2296234..2296698 (+)	465	WP_002894012.1	CtsR family transcriptional regulator	-
FOC72_RS11210 (FOC72_11210)	clpC	2296699..2299128 (+)	2430	WP_002894011.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FOC72_RS11215 (FOC72_11215)	-	2299254..2299964 (+)	711	WP_002894009.1	DUF4272 domain-containing protein	-
FOC72_RS11220 (FOC72_11220)	-	2300007..2300492 (+)	486	WP_002894008.1	hypothetical protein	-
FOC72_RS11225 (FOC72_11225)	-	2300476..2300877 (+)	402	WP_002894007.1	DUF4430 domain-containing protein	-
FOC72_RS11230 (FOC72_11230)	-	2301064..2302122 (+)	1059	WP_002894006.1	AAA family ATPase	-
FOC72_RS11235 (FOC72_11235)	pnuC	2302144..2302959 (+)	816	WP_002894005.1	nicotinamide riboside transporter PnuC	-
FOC72_RS11240 (FOC72_11240)	-	2303014..2303802 (+)	789	WP_002894004.1	NUDIX hydrolase	-

Sequence

Protein

• Length: 809 a.a.
• Molecular weight: 89676.20 Da
• Isoelectric Point: 5.1953

>NTDB_id=453533 FOC72_RS11210 WP_002894011.1 2296699..2299128(+) (clpC) [Streptococcus sanguinis strain FDAARGOS_770]
MKYSKALIESLEAAQLLAGHFTTDYLESWHLLIALANNPYSVAGSVLNEFPVEVDGFEEAAFQITGQAYQKDGHFELLPF
SYRLEELFEEAGQISEAVRAKHVGTEHVLLAMLFDRGTLASRILEFTGFSYEDKEQGLKISDLRKVLEQRAGWGKEDIKA
IRSLNKGVMAAKQTMANMMGMPASTSGGLEDYTRDLTELARDGRLEPVIGRDQEISRIVQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPAELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEEDGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVSIEEPNVADSIAILQGLRKSYEDHHKVQISDQAIET
AVKYAHRYLTSKHLPDSAIDLLDEASATVQNRGPQNYEQSDLTPVDQALMAADFKKVSQLLEQEQQPKLYKLKVEEDDVL
ATLSSLSGIPVQKLTQTDAKKYLNLETELHKRVIGQDEAISAISRAIRRNQSGIRSSKRPIGSFMFLGPTGVGKTELAKA
LAESLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
QLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDIRLDHANMEKRMLEELKKAYRPEFINRIDEKVVFHSLSAE
DMQEVVKVMVKPLIASLAEKGIELKFQASALKLLAQEGYDVEMGARPLRRTLQTQVEDKLSELLLTGDLTTGQTLKVGVK
AGQLKFEVA

Nucleotide

• Length: 2430 bp

>NTDB_id=453533 FOC72_RS11210 WP_002894011.1 2296699..2299128(+) (clpC) [Streptococcus sanguinis strain FDAARGOS_770]
ATGAAATACTCAAAAGCCTTAATAGAAAGCTTGGAAGCAGCCCAGCTCTTGGCCGGCCATTTTACGACAGATTATCTGGA
ATCATGGCATCTGTTGATTGCTCTGGCTAATAATCCCTACAGCGTTGCTGGTTCAGTTCTCAATGAGTTTCCTGTGGAAG
TGGATGGATTTGAAGAAGCAGCTTTTCAGATTACTGGTCAGGCTTATCAGAAAGACGGTCACTTCGAGCTGCTGCCTTTT
TCTTATCGCTTAGAGGAGCTGTTTGAGGAAGCGGGCCAGATTTCAGAAGCTGTTCGCGCTAAGCATGTAGGTACTGAGCA
TGTGCTGCTGGCCATGCTATTTGACCGAGGGACCTTGGCTTCTCGTATCCTGGAATTTACTGGCTTTAGCTACGAGGACA
AGGAGCAGGGACTGAAAATTAGTGATTTGCGAAAGGTCTTGGAGCAGCGAGCTGGCTGGGGCAAGGAAGATATCAAGGCT
ATCCGCAGTCTGAATAAGGGAGTAATGGCAGCCAAGCAGACCATGGCTAATATGATGGGGATGCCGGCTTCTACCAGCGG
GGGGCTGGAAGATTACACCCGTGATCTGACGGAGCTGGCTAGAGATGGCCGATTGGAGCCCGTCATTGGCCGTGATCAGG
AAATTTCACGAATAGTTCAGATTCTCAGTCGCAAGACTAAAAACAATCCAGTGCTGGTTGGAGATGCTGGGGTTGGTAAG
ACAGCTCTGGCCTTAGGACTGGCTCAGCGTGTAGCGGCTGGTCAGGTTCCCGCTGAACTTGCCAAGATGCGGGTTTTGGA
GCTGGACTTGATGAATGTAGTTGCTGGCACTCGCTTTCGCGGAGACTTCGAGGAGCGGATGAACAATATCATCAATGACA
TTGAAGAAGATGGTCATGTTATTCTTTTCATCGATGAACTTCATACCATCATGGGCTCTGGCAGCGGTATTGACTCGACC
TTGGATGCGGCCAATATCCTGAAACCGGCTCTAGCTCGCGGAACATTGCGGACAGTTGGTGCTACGACGCAGGAAGAGTA
TCAGAAACATATTGAAAAAGATGCTGCCCTTTCTCGGCGTTTTGCCAAGGTCAGCATAGAAGAGCCTAATGTGGCCGACA
GCATTGCTATTTTACAAGGCTTGAGAAAGAGCTATGAGGACCATCACAAGGTGCAGATTAGTGATCAGGCTATTGAGACG
GCGGTGAAATATGCCCATCGCTATCTGACTAGCAAGCACCTGCCGGACTCTGCCATTGATCTTTTGGACGAGGCCAGTGC
GACAGTGCAGAATAGAGGGCCACAGAATTACGAGCAGTCGGATTTGACGCCAGTGGATCAAGCCTTGATGGCAGCGGATT
TTAAAAAGGTTTCCCAACTGCTTGAGCAAGAGCAGCAACCCAAGCTCTATAAACTGAAAGTGGAAGAAGACGATGTCTTG
GCAACACTTAGTAGCTTGTCTGGTATTCCTGTGCAGAAGCTGACTCAGACAGATGCGAAGAAATACCTCAATTTGGAAAC
AGAATTGCATAAACGCGTGATTGGGCAGGACGAGGCGATTTCAGCTATCAGCCGAGCTATCCGACGGAACCAGTCTGGTA
TCCGCAGCAGCAAGCGTCCGATTGGCTCCTTTATGTTCCTAGGTCCGACAGGAGTCGGAAAAACAGAGCTAGCCAAGGCC
TTGGCCGAAAGTCTCTTTGATGACGAATCTGCCCTCATCCGCTTTGATATGAGTGAGTACATGGAGAAATTCGCGGCTAG
CCGTCTCAACGGAGCGCCTCCAGGTTATGTAGGCTATGAAGAAGGAGGGGAGCTGACGGAAAAGGTGCGCAACCGACCTT
ATTCTGTCCTACTCTTTGACGAGGTGGAAAAGGCGCATCCAGATATTTTCAATGTCCTCCTCCAGGTCTTGGATGATGGT
CAGCTGACGGACAGCAAGGGTCGCAAGGTGGACTTCTCCAACACGATTATTATCATGACCAGCAATCTGGGGGCAACCAG
TTTGCGGGATGATAAGACGGTGGGCTTTGGAGCGCGCGATATTCGCTTGGACCATGCCAATATGGAAAAACGGATGCTGG
AAGAGCTTAAGAAAGCATATCGACCAGAGTTTATCAACCGTATTGACGAGAAAGTAGTCTTCCACAGCTTATCTGCAGAA
GATATGCAGGAAGTGGTCAAGGTTATGGTCAAACCGCTCATTGCCAGTCTTGCTGAGAAGGGAATTGAGCTGAAGTTCCA
GGCTAGTGCCCTTAAGCTACTGGCTCAGGAAGGCTACGATGTGGAAATGGGAGCACGGCCATTGCGCCGCACTCTGCAGA
CTCAAGTAGAGGACAAGCTGTCTGAGCTACTCTTGACAGGAGATTTGACAACAGGTCAAACTCTTAAGGTCGGGGTCAAA
GCTGGCCAACTCAAGTTCGAAGTGGCCTAG

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-136)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-60)

• AAA domain (Cdc48 subfamily) (AAA_2) (539-710)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-797)

• AAA lid domain (AAA_lid_9) (371-463)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	77.654	100	0.777
clpC	Streptococcus pneumoniae D39	77.654	100	0.777
clpC	Streptococcus pneumoniae TIGR4	77.654	100	0.777
clpC	Streptococcus mutans UA159	68.059	100	0.685
clpC	Streptococcus thermophilus LMG 18311	66.544	100	0.669
clpC	Streptococcus thermophilus LMD-9	66.421	100	0.667
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.484	100	0.515
clpC	Bacillus subtilis subsp. subtilis str. 168	45.693	99.011	0.452
clpE	Streptococcus mutans UA159	47.65	76.267	0.363