Detailed information NTG0453508

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FOC72_RS07130
• Genome accession: NZ_CP054570
• Coordinates: 1496753..1497796 (-)
• Length: 347 a.a.
• NCBI ID: WP_002896216.1
• Uniprot ID: A0A859ENR2
• Organism: Streptococcus sanguinis strain FDAARGOS_770
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1491753..1502796

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC72_RS07110 (FOC72_07110)	trpB	1492831..1494012 (-)	1182	WP_002896210.1	tryptophan synthase subunit beta	-
FOC72_RS07115 (FOC72_07115)	-	1494403..1494918 (-)	516	WP_002896211.1	VanZ family protein	-
FOC72_RS07120 (FOC72_07120)	rlmN	1494905..1495993 (-)	1089	WP_002896212.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
FOC72_RS07125 (FOC72_07125)	-	1495990..1496571 (-)	582	WP_002896213.1	YutD-like domain-containing protein	-
FOC72_RS07130 (FOC72_07130)	sepM	1496753..1497796 (-)	1044	WP_002896216.1	SepM family pheromone-processing serine protease	Regulator
FOC72_RS07135 (FOC72_07135)	coaD	1497783..1498277 (-)	495	WP_002896217.1	pantetheine-phosphate adenylyltransferase	-
FOC72_RS07140 (FOC72_07140)	rsmD	1498267..1498815 (-)	549	WP_002896218.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FOC72_RS07145 (FOC72_07145)	-	1498885..1499373 (-)	489	WP_002896219.1	YcxB family protein	-
FOC72_RS07150 (FOC72_07150)	-	1499516..1500193 (+)	678	WP_002896221.1	XRE family transcriptional regulator	-
FOC72_RS07155 (FOC72_07155)	-	1500198..1501613 (+)	1416	WP_002896223.1	Y-family DNA polymerase	-
FOC72_RS07160 (FOC72_07160)	-	1501610..1501984 (+)	375	WP_002896227.1	hypothetical protein	-
FOC72_RS07165 (FOC72_07165)	-	1501962..1502255 (+)	294	WP_002896228.1	DUF5960 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38003.20 Da
• Isoelectric Point: 5.0310

>NTDB_id=453508 FOC72_RS07130 WP_002896216.1 1496753..1497796(-) (sepM) [Streptococcus sanguinis strain FDAARGOS_770]
MKRIKKFILPTVIGVTIAFFIAALYVRLPYYIEVPGGAEDVRQVLLVDNKADKEAGSYNFVTVGVEQATFAHLVYAWLTP
FTDIYSAKDMTGGSTDEEFNRINQFYMETSQNMAKYQGLTTAGKEIKMDYLGVYVLQVADNSTFKGVLNIADTVTGVNDK
TFESSEELVKYVNSQKLGDKIKVTFQEDGQEKSETGKVIKLENGKNGIGISLIDRTEVSSNIPITFSTEGIGGPSAGLMF
SLAIYTQLADPTLRDGRDIAGTGSISREGEVGEIGGINKKVVSAAQSGADIFFAPNNELTEEEKKLSPNGKNNYQTALET
AKKIKTDMKIVPVKTLQDAIDYLKKNK

Nucleotide

• Length: 1044 bp

>NTDB_id=453508 FOC72_RS07130 WP_002896216.1 1496753..1497796(-) (sepM) [Streptococcus sanguinis strain FDAARGOS_770]
ATGAAAAGAATTAAGAAGTTTATATTGCCGACGGTCATTGGCGTCACTATTGCCTTTTTTATAGCAGCTCTTTACGTTCG
TCTGCCTTATTATATAGAAGTTCCTGGTGGTGCCGAGGATGTTCGTCAGGTCTTGCTGGTTGATAATAAGGCCGACAAGG
AAGCGGGTTCCTACAACTTTGTGACGGTCGGAGTAGAGCAGGCAACCTTTGCTCATCTGGTCTATGCTTGGCTGACCCCT
TTTACAGATATTTATTCTGCCAAGGATATGACGGGTGGCTCCACGGATGAAGAGTTCAATCGGATCAACCAATTTTACAT
GGAAACATCACAAAATATGGCTAAATATCAAGGGTTGACAACGGCTGGTAAAGAGATCAAAATGGACTATCTGGGAGTTT
ATGTCTTGCAGGTGGCTGATAACTCAACCTTCAAGGGAGTTCTCAATATTGCTGATACGGTAACTGGTGTCAATGATAAG
ACATTTGAAAGCTCTGAGGAGCTGGTTAAGTATGTCAACTCGCAGAAGCTTGGGGATAAAATCAAGGTGACTTTCCAAGA
AGATGGTCAGGAGAAATCAGAAACTGGTAAGGTTATCAAGTTGGAGAACGGTAAGAACGGGATTGGGATTAGTCTGATAG
ACCGGACGGAAGTCAGCAGTAATATTCCGATTACATTTTCAACTGAGGGTATCGGCGGTCCTAGTGCTGGTCTCATGTTC
AGTCTCGCTATTTATACCCAGTTGGCTGATCCGACCCTTCGTGACGGCCGCGATATTGCAGGGACCGGCAGCATCAGCCG
AGAAGGCGAAGTTGGTGAAATCGGCGGAATCAATAAGAAAGTCGTTTCAGCGGCCCAAAGCGGAGCAGACATCTTCTTTG
CACCGAACAATGAACTTACAGAGGAAGAGAAAAAGCTTTCTCCTAATGGGAAAAACAACTACCAAACGGCTCTGGAGACA
GCCAAGAAGATTAAAACGGATATGAAAATTGTTCCAGTTAAAACGCTGCAGGACGCCATTGACTATCTGAAAAAGAACAA
GTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (128-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-300)

3D structure

• AlphaFold DB: A0A859ENR2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	57.225	99.712	0.571