Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   I6H78_RS00615 Genome accession   NZ_CP066059
Coordinates   130282..130746 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 125282..135746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS00585 (I6H78_00585) - 125774..126184 (+) 411 WP_198459598.1 hypothetical protein -
  I6H78_RS00590 (I6H78_00590) - 126340..127254 (+) 915 WP_198459599.1 peptidase -
  I6H78_RS00595 (I6H78_00595) - 127493..128431 (+) 939 WP_198459600.1 FRG domain-containing protein -
  I6H78_RS00600 (I6H78_00600) - 128490..129182 (+) 693 WP_198459601.1 YjjG family noncanonical pyrimidine nucleotidase -
  I6H78_RS00605 (I6H78_00605) - 129206..129499 (+) 294 WP_084881808.1 hypothetical protein -
  I6H78_RS00610 (I6H78_00610) - 129619..130272 (+) 654 WP_198459602.1 uracil-DNA glycosylase -
  I6H78_RS00615 (I6H78_00615) mutX 130282..130746 (+) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  I6H78_RS00620 (I6H78_00620) - 130759..132027 (+) 1269 WP_198459603.1 dihydroorotase -
  I6H78_RS00625 (I6H78_00625) - 132069..133409 (+) 1341 WP_198459604.1 MATE family efflux transporter -
  I6H78_RS00630 (I6H78_00630) - 133588..134556 (+) 969 WP_198459605.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  I6H78_RS00635 (I6H78_00635) - 134572..135564 (+) 993 WP_198459606.1 alpha-ketoacid dehydrogenase subunit beta -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=453398 I6H78_RS00615 WP_001135768.1 130282..130746(+) (mutX) [Streptococcus oralis strain FDAARGOS_1021]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=453398 I6H78_RS00615 WP_001135768.1 130282..130746(+) (mutX) [Streptococcus oralis strain FDAARGOS_1021]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAACGGAAAAGAACTGCTCATGCTCCATCGTAATAAGAAGCCCAACGA
TGTCCATGAAGGCAAATGGATTGGTGTGGGTGGAAAGCTAGAGCGAGGTGAGACTCCACAGGAATGTGCAGCGCGTGAAA
TCCTCGAAGAAACAGGGCTCAAAGCCAAGCCGGTTCTAAAAGGTGTTATCACTTTTCCAGAATTCACGCCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGTGACTTGATTGACTGCAATGAGGGAACCTTAGAATGGGTTCC
CTATGATGAAGTCTTGAGCAAGCCAACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGACAAACCTTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987