Detailed information NTG0453315

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: I6H72_RS04070
• Genome accession: NZ_CP066055
• Coordinates: 826855..827910 (-)
• Length: 351 a.a.
• NCBI ID: WP_070669255.1
• Uniprot ID: A0A380L396
• Organism: Streptococcus constellatus strain FDAARGOS_1015
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 821855..832910

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H72_RS04045 (I6H72_04045)	-	823037..823564 (-)	528	WP_006267546.1	Dps family protein	-
I6H72_RS04050 (I6H72_04050)	cclA/cilC	823715..824389 (+)	675	WP_020997643.1	prepilin peptidase	Machinery gene
I6H72_RS04055 (I6H72_04055)	-	824384..824902 (-)	519	WP_003070167.1	VanZ family protein	-
I6H72_RS04060 (I6H72_04060)	rlmN	824895..825977 (-)	1083	WP_049476508.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
I6H72_RS04065 (I6H72_04065)	-	826011..826568 (-)	558	WP_003070172.1	YutD family protein	-
I6H72_RS04070 (I6H72_04070)	sepM	826855..827910 (-)	1056	WP_070669255.1	SepM family pheromone-processing serine protease	Regulator
I6H72_RS04075 (I6H72_04075)	coaD	827891..828388 (-)	498	WP_006267255.1	pantetheine-phosphate adenylyltransferase	-
I6H72_RS04080 (I6H72_04080)	rsmD	828378..828917 (-)	540	WP_020997641.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
I6H72_RS04085 (I6H72_04085)	hpf	829114..829656 (-)	543	WP_003032381.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
I6H72_RS04090 (I6H72_04090)	comFC/cflB	829735..830400 (-)	666	WP_006267632.1	ComF family protein	Machinery gene
I6H72_RS04095 (I6H72_04095)	comFA/cflA	830397..831698 (-)	1302	WP_198458343.1	DEAD/DEAH box helicase	Machinery gene
I6H72_RS04100 (I6H72_04100)	-	831755..832390 (+)	636	WP_003035211.1	YigZ family protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38315.36 Da
• Isoelectric Point: 10.2305

>NTDB_id=453315 I6H72_RS04070 WP_070669255.1 826855..827910(-) (sepM) [Streptococcus constellatus strain FDAARGOS_1015]
MEKSRTKFKKWPIVAVVGLLLLFMSFIVPLPYYIEVPGGAADVRQVLRVDNKVDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKDLIDYVGSQKIGSKVKVNYVEDGQKKSAIGKIIKLENGKNGIGISLIDRTEVTSNIPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=453315 I6H72_RS04070 WP_070669255.1 826855..827910(-) (sepM) [Streptococcus constellatus strain FDAARGOS_1015]
ATGGAAAAATCACGAACTAAATTTAAAAAATGGCCGATAGTGGCTGTAGTAGGGCTGCTTCTACTGTTCATGTCTTTTAT
AGTTCCTCTGCCTTATTACATTGAGGTGCCAGGTGGTGCAGCAGATGTTCGGCAAGTATTACGTGTAGATAATAAAGTGG
ATAAGGAAAAAGGTTCTTATAACTTTGTCACTGTTGGGATTCAGCATGCAACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACTCCTTTTACAGATATTTATTCGGCGAAAGATCTGACTGGCGGAACTTCTGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGGTTAAAAAAAGCAGGCAAGGATATTAGCTTGAAATATTTGG
GTGTTTATGTGTTGCAAGTTACCAAGAATTCAACCTTTAAAGGGATTCTAAATATTGCAGATACTGTGACAGGCGTGAAT
GATAAGACTTTCAACAGTTCAAAAGATTTGATTGATTATGTAGGCTCACAGAAAATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAAAAATCTGCTATAGGTAAAATTATCAAACTTGAAAATGGGAAAAATGGAATTGGTATTAGCT
TAATTGACCGAACAGAAGTCACAAGTAATATACCAATTGAATTTTCAACAGCTGGGATTGGTGGACCAAGTGCGGGTTTA
ATGTTTAGCTTGGCGATTTATACACAGATTGCAGACCCGACATTGAGAGATGGCAGAAATATTGCTGGGACAGGATCGAT
TGACCGTGAAGGAAAAGTTGGTGATATTGGTGGGATTGATAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAAAG
TACTAAAAAATCTTAA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (133-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (234-307)

3D structure

• AlphaFold DB: A0A380L396

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	63.663	98.006	0.624