Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H85_RS02715 Genome accession   NZ_CP066027
Coordinates   526091..527905 (+) Length   604 a.a.
NCBI ID   WP_002777497.1    Uniprot ID   A0ABN0EPQ0
Organism   Campylobacter coli strain FDAARGOS_1028     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 521091..532905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H85_RS02695 (I6H85_02695) - 521641..522249 (-) 609 WP_002777505.1 class I SAM-dependent DNA methyltransferase -
  I6H85_RS09970 - 522449..522580 (+) 132 WP_256374849.1 hypothetical protein -
  I6H85_RS02700 (I6H85_02700) - 522571..523818 (+) 1248 WP_002777503.1 RNA-guided endonuclease InsQ/TnpB family protein -
  I6H85_RS02705 (I6H85_02705) guaA 523950..525485 (-) 1536 WP_002777501.1 glutamine-hydrolyzing GMP synthase -
  I6H85_RS02710 (I6H85_02710) - 525622..526098 (+) 477 WP_002777499.1 hypothetical protein -
  I6H85_RS02715 (I6H85_02715) uvrC 526091..527905 (+) 1815 WP_002777497.1 excinuclease ABC subunit UvrC Machinery gene
  I6H85_RS02720 (I6H85_02720) - 527907..529100 (+) 1194 WP_002777493.1 hypothetical protein -
  I6H85_RS02725 (I6H85_02725) - 529097..529999 (-) 903 WP_002777490.1 radical SAM protein -
  I6H85_RS02730 (I6H85_02730) hemE 529996..531018 (-) 1023 WP_002777488.1 uroporphyrinogen decarboxylase -
  I6H85_RS02735 (I6H85_02735) - 531166..531477 (-) 312 WP_002777486.1 hypothetical protein -
  I6H85_RS02740 (I6H85_02740) - 531720..532325 (+) 606 WP_002777482.1 hypothetical protein -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 69707.68 Da        Isoelectric Point: 9.1921

>NTDB_id=453061 I6H85_RS02715 WP_002777497.1 526091..527905(+) (uvrC) [Campylobacter coli strain FDAARGOS_1028]
MAEILLKNTLKEELQTLPANAGVYQYFNAEGKLLYVGKAKNLKNRVRSYFAFAPNLRANPKNSLRIQKMIEEAVHLEFIT
TNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFNEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYP
LKQKASCKSPCIFYQISRCLAPCDKKITQEEYRLILDKAINALLSPSILVKNLEKQMFHLAQNENYEEAAKIRDQIATIR
DLEIKVEIDIAKLEDFEIFALACESSMLSTLRFVVQNGKIISANSKITPLKNNTDFDKNEIYKQLILENFSVDIPLVANT
VYVYEDFEDRELLEEILSQRFDKKISIKVPKIGEKRRICDLAFQNACLNIQKEQKNSDFNIQKELKNYFELENLPNCIEV
FDNSHLQGVANVGAMITYKMGTWDKSNYRKFHLKYKNDYEQMREVLTRRALEFDKMPAPDLWLIDGGKALLDLAKEIILS
SGANVDILAISKEKINAKAHRAKGGAKDKIHSLKGEFALSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLSSSKLVK
SGLSAGVIQKLLAYYGSFEAIYEANFEELCQLVGKKSAQKIKED

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=453061 I6H85_RS02715 WP_002777497.1 526091..527905(+) (uvrC) [Campylobacter coli strain FDAARGOS_1028]
ATGGCTGAAATTTTACTTAAAAATACTCTCAAAGAAGAGCTTCAAACCCTACCTGCAAATGCTGGAGTGTATCAGTATTT
TAATGCCGAAGGAAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAACCGCGTAAGATCTTATTTTGCTTTTGCCC
CAAATTTACGCGCCAATCCAAAAAATTCTTTAAGAATTCAAAAAATGATAGAAGAAGCGGTGCATTTGGAATTTATTACA
ACAAATTCAGAAGCTGATGCTTTGATTTTGGAAAATTCTTTTATCAAGCAACTTCATCCAAAATACAATATTTTACTAAG
AGATGATAAGACTTATCCTTATATTTATGTAGATTTTAATGAAGAATTTCCGCGTTTTGAAATCACTAGAAAATTAGTTA
AAAAAAGTAAAATCAAATATTTTGGCCCCTTTTTTAAAGGAGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCT
TTAAAGCAAAAAGCAAGTTGTAAATCTCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAAAAAAT
TACCCAAGAAGAATATCGTTTGATTTTAGATAAAGCTATCAATGCTCTTTTAAGCCCTAGTATTTTAGTGAAAAATTTGG
AAAAACAAATGTTTCATTTAGCCCAAAATGAGAATTATGAAGAAGCGGCAAAAATAAGAGATCAGATTGCTACGATAAGG
GATTTGGAAATTAAAGTTGAGATTGATATCGCTAAATTAGAAGACTTTGAAATTTTTGCTTTAGCTTGTGAAAGCTCTAT
GCTTTCAACTTTGCGTTTTGTGGTGCAAAATGGAAAAATCATCAGCGCTAATTCTAAAATCACTCCGCTTAAAAACAATA
CAGATTTTGATAAAAATGAGATTTATAAACAGCTTATTTTAGAAAATTTTAGCGTAGACATTCCTTTGGTTGCAAATACT
GTTTATGTTTATGAGGATTTTGAAGACAGGGAGCTTTTAGAAGAAATTTTAAGCCAGAGATTTGATAAAAAAATCAGCAT
TAAAGTTCCTAAAATAGGGGAAAAAAGAAGAATTTGTGATTTGGCATTTCAAAATGCGTGTTTAAATATACAAAAAGAGC
AAAAAAATAGTGATTTTAATATACAAAAAGAACTTAAAAATTATTTCGAGCTTGAAAATCTGCCAAATTGTATAGAAGTT
TTTGATAATTCTCATTTGCAAGGTGTGGCGAATGTAGGAGCTATGATAACTTATAAAATGGGTACTTGGGATAAGTCAAA
TTATAGAAAATTTCATTTAAAATACAAAAATGATTATGAGCAAATGCGTGAAGTTTTAACGCGTAGAGCATTAGAATTTG
ACAAAATGCCTGCTCCTGATTTGTGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTAGCTAAAGAAATCATCTTAAGT
AGTGGGGCAAATGTTGATATTTTAGCAATCTCAAAAGAAAAAATCAATGCTAAAGCTCACCGCGCTAAAGGAGGGGCTAA
AGATAAAATTCACTCTTTAAAAGGAGAATTTGCCCTAAGCATTAACGATAAAAAATTACAATTCTTACAGAAATTAAGAG
ATGAAGCACATCGTTTTGCCATAAGTTTTCATCAAAACACTAAGAAAAAACAAGATTTATCAAGCTCTAAGCTTGTAAAA
TCAGGACTTAGTGCGGGAGTTATACAAAAACTTTTGGCGTATTATGGAAGTTTTGAAGCTATTTATGAGGCAAATTTTGA
AGAATTGTGCCAATTAGTAGGAAAAAAATCAGCACAAAAAATAAAGGAAGATTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(387-541)

GIY-YIG catalytic domain (GIY-YIG)

(21-103)

UvrB/uvrC motif (UVR)

(209-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

45.812

96.854

0.444