Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   I6H77_RS08670 Genome accession   NZ_CP066021
Coordinates   1813057..1813521 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1808057..1818521
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS08645 (I6H77_08645) - 1808358..1808774 (+) 417 WP_000110627.1 Imm70 family immunity protein -
  I6H77_RS08650 (I6H77_08650) - 1809115..1810404 (+) 1290 WP_000411457.1 hypothetical protein -
  I6H77_RS08655 (I6H77_08655) - 1810414..1811508 (+) 1095 WP_001055022.1 AI-2E family transporter -
  I6H77_RS08660 (I6H77_08660) - 1811640..1812332 (+) 693 WP_001146400.1 YjjG family noncanonical pyrimidine nucleotidase -
  I6H77_RS08665 (I6H77_08665) - 1812394..1813047 (+) 654 WP_001164853.1 uracil-DNA glycosylase -
  I6H77_RS08670 (I6H77_08670) mutX 1813057..1813521 (+) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  I6H77_RS08675 (I6H77_08675) - 1813534..1814802 (+) 1269 WP_000924511.1 dihydroorotase -
  I6H77_RS08680 (I6H77_08680) - 1814844..1816184 (+) 1341 WP_000283624.1 MATE family efflux transporter -
  I6H77_RS08685 (I6H77_08685) - 1816364..1817332 (+) 969 WP_000105349.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  I6H77_RS08690 (I6H77_08690) - 1817349..1818341 (+) 993 WP_000448714.1 alpha-ketoacid dehydrogenase subunit beta -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=453038 I6H77_RS08670 WP_001135768.1 1813057..1813521(+) (mutX) [Streptococcus oralis strain FDAARGOS_1020]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=453038 I6H77_RS08670 WP_001135768.1 1813057..1813521(+) (mutX) [Streptococcus oralis strain FDAARGOS_1020]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAACGGAAAAGAACTGCTCATGCTCCATCGCAATAAGAAGCCCAACGA
TGTCCATGAAGGCAAATGGATTGGTGTGGGTGGAAAGCTAGAGCGAGGTGAGACTCCACAGGAATGTGCAGCGCGTGAAA
TCCTCGAAGAAACAGGGCTCAAAGCCAAGCCAGTACTTAAAGGTGTTATCACTTTTCCTGAATTTACGCCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACAGAGTTCGAGGGTGACTTGATTGACTGCAATGAGGGGACCTTAGAATGGGTTCC
CTATGATGAAGTCTTAAGCAAGCCAACTTGGGAGGGTGATCACACCTTTGTTGAGTGGCTTTTAGAAGATAAACCTTTCT
TTTCAGCAAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987