Detailed information NTG0453012

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I6H77_RS05510
• Genome accession: NZ_CP066021
• Coordinates: 1136323..1138428 (+)
• Length: 701 a.a.
• NCBI ID: WP_001063422.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_1020
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1131323..1143428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H77_RS05505 (I6H77_05505)	-	1131791..1135870 (+)	4080	WP_000045550.1	Spy0128 family protein	-
I6H77_RS05510 (I6H77_05510)	clpE	1136323..1138428 (+)	2106	WP_001063422.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6H77_RS05515 (I6H77_05515)	-	1138489..1138971 (-)	483	WP_000032557.1	S-ribosylhomocysteine lyase	-
I6H77_RS05520 (I6H77_05520)	-	1139267..1139974 (+)	708	WP_000400162.1	ABC transporter ATP-binding protein	-
I6H77_RS05525 (I6H77_05525)	-	1139976..1140764 (+)	789	WP_000665373.1	lantibiotic ABC transporter permease	-
I6H77_RS05530 (I6H77_05530)	-	1140764..1141486 (+)	723	WP_000588279.1	hypothetical protein	-
I6H77_RS05535 (I6H77_05535)	-	1141499..1142197 (+)	699	WP_000404920.1	response regulator transcription factor	-
I6H77_RS05540 (I6H77_05540)	-	1142164..1143195 (+)	1032	WP_001007878.1	sensor histidine kinase	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77446.22 Da
• Isoelectric Point: 4.7639

>NTDB_id=453012 I6H77_RS05510 WP_001063422.1 1136323..1138428(+) (clpE) [Streptococcus oralis strain FDAARGOS_1020]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAEVDGQMQQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSIQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNAKTRIAELEKKVANHTEDMKVTASINDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLEHKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLNKEDLSKIVDLMLAEVNQTLAKKDIDLEVS
QAAKDFITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide

• Length: 2106 bp

>NTDB_id=453012 I6H77_RS05510 WP_001063422.1 1136323..1138428(+) (clpE) [Streptococcus oralis strain FDAARGOS_1020]
ATGAACAACAACTTTAATAACTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTC
TGAAAATCGTCGCTACCTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGC
CAGGTAATGCAGAAGTTGATGGACAAATGCAACAACAGGCTTCAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGT
CGTAACTTGACAGCGGAAGCTCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGTCGTACGAAAAATAATCCTGTTCTGGTCGGAGATGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGCT
TGGCACAAGCTATTGTGAATGGAGATGTTCCAGCTGCCATCAAGAATAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAAGCTGGTACTCAATACCGTGGCAGCTTTGAAGAAAACGTTCAAAATCTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTCGGTGCTGGTAGCACTGGTGGAGACAGTGGATCTAAAGGGCTTGCGG
ACATTCTCAAGCCAGCTCTCTCTCGTGGTGAGTTGACTGTTATTGGGGCAACGACTCAAGACGAATACCGTAATACCATC
TTGAAAAATGCAGCACTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCAGCAGAGGATACCTTTAAAATCCT
TCAAGGGATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTATCCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTGGACGTAACGGCTGCTCACTTGGCAGCT
CAACATCCTGTAACAGATGTGCATGCTGTTGAACGGGAGATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGACTTTGAAGCAGCTCTTAATGCTAAGACACGCATTGCTGAATTAGAGAAAAAAGTCGCAAACCACACAGAAGACA
TGAAAGTGACTGCAAGCATCAACGATGTGGCTGAGTCTGTGGAACGAATGACAGGTATTCCAGTGTCACAAATGGGAGCG
TCAGACATCGAACGTTTGAAAGATATGGCTCATCGCTTGGAACACAAGGTAATCGGCCAAGATAAGGCAGTAGAAGCAGT
GGCTCGTGCTATCCGTCGTAACCGCGCTGGTTTTGATGAAGGCAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGGCCTA
CTGGAGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCGCTCGATATGTTTGGTACCAAGGATGCGATTATCCGCTTGGAT
ATGTCTGAATACAGTGACCGCACAGCCGTTTCTAAATTGATCGGTACAACAGCAGGTTATGTGGGTTATGATGACAATAG
CAATACCTTGACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGACGAAATTGAAAAGGCTGATCCTCAAG
TCATTACCCTTCTCCTCCAAGTCTTGGATGATGGTCGTTTGACTGATGGTCAAGGAAATACAGTGAACTTCAAGAACACA
GTCATTATCGCGACATCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAGCCAGAATTGATGGA
TCGTTTGAAACCATTCTTCCGCCCAGAGTTCCTTAACCGCTTTAACGCAGTTATCGAATTCTCACACTTGAATAAGGAAG
ACCTTTCTAAGATTGTGGACTTGATGTTGGCGGAAGTCAACCAAACCTTGGCTAAGAAAGACATTGATTTGGAAGTCAGC
CAAGCAGCTAAAGACTTTATCACAGAAGAAGGTTATGACGAAGTTATGGGTGTTCGCCCTCTCCGTCGCGTGGTGGAACA
ACAAATTCGTGATAAGGTAACAGATTTCCACTTGGATCATCTAGATGCCAAACATTTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAAAAAGCCTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (610-680)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-603)

• AAA lid domain (AAA_lid_9) (259-354)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	50.776	91.869	0.466
clpC	Lactococcus lactis subsp. cremoris KW2	50	91.298	0.456
clpE	Streptococcus pneumoniae TIGR4	48.896	90.442	0.442
clpE	Streptococcus pneumoniae Rx1	48.585	90.728	0.441
clpE	Streptococcus pneumoniae D39	48.585	90.728	0.441
clpE	Streptococcus pneumoniae R6	48.585	90.728	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	44.87	93.153	0.418
clpC	Streptococcus pneumoniae D39	43.61	89.301	0.389
clpC	Streptococcus pneumoniae Rx1	43.61	89.301	0.389
clpC	Streptococcus pneumoniae TIGR4	43.45	89.301	0.388
clpC	Streptococcus thermophilus LMD-9	42.973	88.302	0.379
clpC	Streptococcus thermophilus LMG 18311	42.811	88.302	0.378
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.788	88.017	0.377
clpC	Streptococcus mutans UA159	42.071	88.16	0.371