Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6H76_RS03495 Genome accession   NZ_CP065994
Coordinates   694794..695438 (-) Length   214 a.a.
NCBI ID   WP_006531177.1    Uniprot ID   A0ABP2DKG8
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 689794..700438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS03470 (I6H76_03470) comFA/cflA 689805..691103 (-) 1299 WP_006531182.1 DEAD/DEAH box helicase Machinery gene
  I6H76_RS03475 (I6H76_03475) - 691158..691784 (+) 627 WP_006531181.1 YigZ family protein -
  I6H76_RS03480 (I6H76_03480) cysK 691884..692813 (+) 930 WP_006531180.1 cysteine synthase A -
  I6H76_RS03485 (I6H76_03485) - 692914..693270 (-) 357 WP_006531179.1 S1 RNA-binding domain-containing protein -
  I6H76_RS03490 (I6H76_03490) - 693270..694670 (-) 1401 WP_081442254.1 Cof-type HAD-IIB family hydrolase -
  I6H76_RS03495 (I6H76_03495) vraR 694794..695438 (-) 645 WP_006531177.1 response regulator transcription factor Regulator
  I6H76_RS03500 (I6H76_03500) - 695422..696447 (-) 1026 WP_006531176.1 sensor histidine kinase -
  I6H76_RS03505 (I6H76_03505) liaF 696444..697139 (-) 696 WP_006531175.1 cell wall-active antibiotics response protein LiaF -
  I6H76_RS03510 (I6H76_03510) stkP/pknB 697237..699126 (-) 1890 WP_006531174.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6H76_RS03515 (I6H76_03515) - 699126..699863 (-) 738 WP_043878264.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24025.88 Da        Isoelectric Point: 5.0501

>NTDB_id=452789 I6H76_RS03495 WP_006531177.1 694794..695438(-) (vraR) [Streptococcus infantarius strain FDAARGOS_1019]
MTQKIRVILVDDHEMVRLGLKSFFNLQPDVEVVGEAGNGIEGIKLALELKPDVVVMDLVMPEMSGVEATLKLLKEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDQKPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDED

Nucleotide


Download         Length: 645 bp        

>NTDB_id=452789 I6H76_RS03495 WP_006531177.1 694794..695438(-) (vraR) [Streptococcus infantarius strain FDAARGOS_1019]
ATGACCCAGAAAATTAGAGTTATCCTAGTTGATGACCACGAAATGGTACGTCTTGGTTTGAAAAGTTTTTTTAACTTGCA
ACCTGACGTTGAAGTTGTTGGCGAAGCAGGCAATGGCATTGAAGGGATAAAACTTGCTTTAGAGTTAAAACCAGATGTGG
TAGTAATGGATTTGGTAATGCCTGAAATGAGTGGCGTTGAAGCGACCTTAAAACTCTTAAAAGAGTGGAAAGAAGCTAAA
ATCCTTGTTCTGACATCTTATCTTGATAATGAAAAAATCTACCCAGTTATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGTGCCGCTGAAATTCTTAACGCCATTCAGAAAGTAGCGCGTGGTGAACTAGCAATCGAAACAGAAGTTGATA
AGAAAATCAAAGCCCACGATCAGAAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGAGATATTTTAAGACTTCTT
GCTAAAGGTTATGACAATCAGACCATTGCTGATGAATTGTTTATTTCACTAAAAACAGTTAAAACCCACGTGTCAAACAT
CTTAGCTAAGCTAGAAGTAGATGACCGCACACAAGCAGTTGTCTATGCCTTTAAGCATCATTTAGTACCGCAAGATGAGG
ATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-119)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.262

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.397