Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HSX12_RS05770 Genome accession   NZ_CP054467
Coordinates   1110942..1111598 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain CF57     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1105942..1116598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSX12_RS05745 (HSX12_05675) oppF 1106472..1107389 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  HSX12_RS05750 (HSX12_05680) - 1107496..1108683 (+) 1188 WP_015417212.1 putative glycoside hydrolase -
  HSX12_RS05755 (HSX12_05685) - 1108801..1109379 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  HSX12_RS05760 (HSX12_05690) spx 1109557..1109952 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  HSX12_RS05765 (HSX12_05695) - 1110010..1110666 (-) 657 WP_033574517.1 TerC family protein -
  HSX12_RS05770 (HSX12_05705) mecA 1110942..1111598 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  HSX12_RS05775 (HSX12_05710) - 1111749..1112909 (+) 1161 WP_033574518.1 competence protein CoiA family protein -
  HSX12_RS05780 (HSX12_05715) pepF 1113137..1114966 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  HSX12_RS05785 (HSX12_05720) - 1115004..1115171 (-) 168 WP_003155026.1 hypothetical protein -
  HSX12_RS05790 (HSX12_05725) spxH 1115457..1116359 (-) 903 WP_039251990.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=452607 HSX12_RS05770 WP_003155032.1 1110942..1111598(+) (mecA) [Bacillus velezensis strain CF57]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=452607 HSX12_RS05770 WP_003155032.1 1110942..1111598(+) (mecA) [Bacillus velezensis strain CF57]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895