Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   STRR_RS08775 Genome accession   NZ_CP065788
Coordinates   1689587..1689880 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain RR     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1684587..1694880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRR_RS08735 (STRR_08660) - 1684989..1685432 (-) 444 WP_011681680.1 hypothetical protein -
  STRR_RS08740 - 1685506..1685844 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  STRR_RS08745 - 1685888..1686163 (-) 276 WP_011681681.1 hypothetical protein -
  STRR_RS08750 (STRR_08670) - 1686175..1686372 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  STRR_RS08755 (STRR_08675) - 1686621..1687814 (-) 1194 WP_014608740.1 acetate kinase -
  STRR_RS08760 (STRR_08680) comGH 1687870..1688826 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  STRR_RS08765 (STRR_08685) comGG 1688871..1689188 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  STRR_RS08770 (STRR_08690) comGF 1689166..1689603 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  STRR_RS08775 (STRR_08695) comGE 1689587..1689880 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  STRR_RS08780 (STRR_08700) comGD 1689852..1690280 (-) 429 WP_257608452.1 competence type IV pilus minor pilin ComGD Machinery gene
  STRR_RS08785 (STRR_08705) comGC 1690240..1690566 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STRR_RS08790 (STRR_08710) comGB 1690563..1691663 (-) 1101 WP_142350125.1 competence type IV pilus assembly protein ComGB Machinery gene
  STRR_RS08795 (STRR_08715) comGA/cglA/cilD 1691545..1692486 (-) 942 WP_071417491.1 competence type IV pilus ATPase ComGA Machinery gene
  STRR_RS08800 (STRR_08720) - 1692567..1692929 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=451320 STRR_RS08775 WP_011226625.1 1689587..1689880(-) (comGE) [Streptococcus thermophilus strain RR]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=451320 STRR_RS08775 WP_011226625.1 1689587..1689880(-) (comGE) [Streptococcus thermophilus strain RR]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361