Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   STMM8_RS07655 Genome accession   NZ_CP065787
Coordinates   1468999..1469730 (+) Length   243 a.a.
NCBI ID   WP_002948869.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MM8     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1463999..1474730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STMM8_RS07625 (STMM8_07610) - 1464121..1464501 (-) 381 WP_022096487.1 hypothetical protein -
  STMM8_RS07630 (STMM8_07615) - 1464626..1464889 (-) 264 WP_002945924.1 hypothetical protein -
  STMM8_RS07635 (STMM8_07620) - 1465211..1465507 (-) 297 WP_004197070.1 bacteriocin immunity protein -
  STMM8_RS07640 (STMM8_07625) - 1465672..1466568 (-) 897 WP_372433431.1 thioredoxin family protein -
  STMM8_RS07645 (STMM8_07630) - 1466791..1468361 (+) 1571 WP_087009847.1 IS3-like element ISSth1b family transposase -
  STMM8_RS07650 (STMM8_07635) - 1468507..1468749 (-) 243 WP_002948868.1 Blp family class II bacteriocin -
  STMM8_RS07655 (STMM8_07640) comE/blpR 1468999..1469730 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  STMM8_RS07660 comD/blpH 1470267..1471070 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  STMM8_RS07665 (STMM8_07650) - 1471088..1471249 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  STMM8_RS07670 (STMM8_07655) - 1471264..1472632 (-) 1369 Protein_1457 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27803.11 Da        Isoelectric Point: 6.9136

>NTDB_id=451199 STMM8_RS07655 WP_002948869.1 1468999..1469730(+) (comE/blpR) [Streptococcus thermophilus strain MM8]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=451199 STMM8_RS07655 WP_002948869.1 1468999..1469730(+) (comE/blpR) [Streptococcus thermophilus strain MM8]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362