Detailed information NTG0451186

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: HRE60_RS07880
• Genome accession: NZ_CP054153
• Coordinates: 1763107..1764183 (-)
• Length: 358 a.a.
• NCBI ID: WP_002884703.1
• Uniprot ID: A0A1W5ZBL0
• Organism: Streptococcus salivarius strain DB-B5
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1758107..1769183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HRE60_RS07855 (HRE60_07855)	-	1758854..1759174 (+)	321	WP_181670669.1	hypothetical protein	-
HRE60_RS07860 (HRE60_07860)	-	1759220..1761286 (-)	2067	WP_181670670.1	sodium:proton antiporter	-
HRE60_RS07865 (HRE60_07865)	-	1761295..1761537 (-)	243	WP_022495909.1	hypothetical protein	-
HRE60_RS07870 (HRE60_07870)	-	1761534..1762082 (-)	549	WP_181670671.1	class I SAM-dependent methyltransferase	-
HRE60_RS07875 (HRE60_07875)	-	1762079..1763023 (-)	945	WP_181670672.1	TIGR01212 family radical SAM protein	-
HRE60_RS07880 (HRE60_07880)	sepM	1763107..1764183 (-)	1077	WP_002884703.1	SepM family pheromone-processing serine protease	Regulator
HRE60_RS07885 (HRE60_07885)	coaD	1764161..1764658 (-)	498	WP_181670673.1	pantetheine-phosphate adenylyltransferase	-
HRE60_RS07890 (HRE60_07890)	rsmD	1764691..1765239 (-)	549	WP_231910681.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
HRE60_RS07895 (HRE60_07895)	trxB	1765380..1766333 (-)	954	WP_255296714.1	thioredoxin-disulfide reductase	-
HRE60_RS07900 (HRE60_07900)	-	1766366..1766590 (-)	225	WP_002884393.1	DUF4059 family protein	-
HRE60_RS07905 (HRE60_07905)	-	1766803..1767546 (-)	744	WP_181670674.1	amino acid ABC transporter ATP-binding protein	-
HRE60_RS07910 (HRE60_07910)	-	1767546..1768292 (-)	747	WP_096832659.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 38988.67 Da
• Isoelectric Point: 9.2472

>NTDB_id=451186 HRE60_RS07880 WP_002884703.1 1763107..1764183(-) (sepM) [Streptococcus salivarius strain DB-B5]
MANKNESKSLLGKIWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVDKKADDSKGSYNFVAVAQTKAT
LALMLYAQLNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAIYQGLTLAGKEASLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSADLIKYVQGLKLGSKVKVTYTTDDKEKTATGKIIKIANGKNGIGIGLTDHTEVKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGSVGDIGGAYLKVKSAADSGADIFFVPNNPVTKEMKKADPD
AKTNYQEAKEAAKKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=451186 HRE60_RS07880 WP_002884703.1 1763107..1764183(-) (sepM) [Streptococcus salivarius strain DB-B5]
GTGGCAAACAAGAACGAATCTAAATCACTATTAGGGAAAATTTGGCGGATTAAGTGGTGGTTGTTAAGTATTTTTACGGT
ACTTTTCCTCCTATTTGCCCTCTTTTTTCCGCTAAATAATTATTATGTTGAGCTTCCGGGTGGTGCTTTTGATACTAAGG
AAGTCTTGACTGTAGACAAGAAAGCTGATGATTCAAAAGGATCCTACAATTTTGTGGCGGTGGCCCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATGCTCAGCTTAATGATTTTGCAAAGCTTCAAACAGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGTATCAACCAATTTTACATGGAGACTTCCCAAAACCAAGCGATTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGCTAGCTTGGAGTATATGGGTGTTTATGTGCTTCAGGTGGCTGATGATTCTAGCTTCAAGGGTGTCCTTAAT
ATTGCGGATACGGTAACAGCTGTCAATGGCAAGACTTTTGATAATTCTGCTGACTTGATTAAATACGTTCAGGGACTTAA
GTTGGGTTCAAAAGTCAAGGTCACTTATACGACAGATGACAAAGAAAAGACTGCCACTGGTAAGATTATCAAGATTGCCA
ATGGTAAAAATGGTATTGGTATCGGTTTGACAGATCATACCGAGGTTAAGAGTCCTGAAAATGTGAAGTTTAAACTTGAT
GGCGTTGGCGGACCAAGTGCGGGTCTTATGTTTACCCTAGCTATTTACGATCAGGTGTCTGGTCAAGATCTCAAGGCTGG
TCGTAAGATTGCTGGAACAGGAACCATTGAAAAGGATGGTTCTGTCGGTGATATCGGTGGTGCCTACCTCAAGGTGAAAT
CAGCGGCTGATAGTGGTGCAGACATTTTCTTTGTACCAAATAATCCAGTAACCAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAACTATCAAGAGGCCAAGGAAGCTGCTAAGAAACTGGGAACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCTATTGATTATTTGAAAAAGACTAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (142-206)

3D structure

• AlphaFold DB: A0A1W5ZBL0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	65.396	95.251	0.623