Detailed information NTG0450421

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: HQ617_RS02860
• Genome accession: NZ_CP054055
• Coordinates: 504939..506012 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain GBS47
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 499939..511012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQ617_RS02830 (HQ617_02810)	-	500832..501896 (+)	1065	WP_000021307.1	MmcQ/YjbR family DNA-binding protein	-
HQ617_RS02835 (HQ617_02815)	asnA	502010..503002 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
HQ617_RS02840 (HQ617_02820)	-	503047..503496 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
HQ617_RS02845 (HQ617_02825)	rsmD	503626..504165 (+)	540	WP_001266830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
HQ617_RS02850 (HQ617_02830)	-	504177..504467 (+)	291	WP_235065604.1	hypothetical protein	-
HQ617_RS02855 (HQ617_02835)	coaD	504464..504949 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
HQ617_RS02860 (HQ617_02840)	sepM	504939..506012 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
HQ617_RS02865 (HQ617_02845)	-	506087..507419 (+)	1333	Protein_481	bifunctional metallophosphatase/5'-nucleotidase	-
HQ617_RS02870 (HQ617_02850)	-	507488..508066 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
HQ617_RS02875 (HQ617_02855)	rlmN	508117..509223 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
HQ617_RS02880 (HQ617_02860)	-	509223..509738 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=450421 HQ617_RS02860 WP_000796095.1 504939..506012(+) (sepM) [Streptococcus agalactiae strain GBS47]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=450421 HQ617_RS02860 WP_000796095.1 504939..506012(+) (sepM) [Streptococcus agalactiae strain GBS47]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658