Detailed information NTG0450367

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: I6G80_RS02635
• Genome accession: NZ_CP065647
• Coordinates: 436689..437765 (-)
• Length: 358 a.a.
• NCBI ID: WP_003178277.1
• Uniprot ID: Q65PD4
• Organism: Bacillus licheniformis strain FDAARGOS_923
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 431689..442765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G80_RS02610 (I6G80_02610)	cysE	431797..432447 (-)	651	WP_003178282.1	serine O-acetyltransferase	-
I6G80_RS02615 (I6G80_02615)	gltX	432749..434206 (-)	1458	WP_003178281.1	glutamate--tRNA ligase	-
I6G80_RS02620 (I6G80_02620)	ispF	434288..434764 (-)	477	WP_003178280.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
I6G80_RS02625 (I6G80_02625)	ispD	434757..435452 (-)	696	WP_003178279.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
I6G80_RS02630 (I6G80_02630)	-	435469..436557 (-)	1089	WP_003178278.1	PIN/TRAM domain-containing protein	-
I6G80_RS02635 (I6G80_02635)	disA	436689..437765 (-)	1077	WP_003178277.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
I6G80_RS02640 (I6G80_02640)	radA/sms	437769..439148 (-)	1380	WP_197942086.1	DNA repair protein RadA	Machinery gene
I6G80_RS02645 (I6G80_02645)	clpC	439228..441660 (-)	2433	WP_003178275.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
I6G80_RS02650 (I6G80_02650)	-	441657..442748 (-)	1092	WP_003178273.1	protein arginine kinase	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 40582.27 Da
• Isoelectric Point: 6.5986

>NTDB_id=450367 I6G80_RS02635 WP_003178277.1 436689..437765(-) (disA) [Bacillus licheniformis strain FDAARGOS_923]
MDKDKKGAKQDLSEILQFVAPGTPLREGIENVLRAKTGGLIVVGFNDKVKEVVDGGFHINSSFSPAHLYELAKMDGAIIL
SDSGQKILYANTQLMPEATIPSSETGMRHRTAERVAKQTGCLIIAISERRNVITLYQENMKYILKDIGFILTKANQAIQT
LEKYKLILDHAISNLNALEFEELVTFGDVISVLHRYEMVLRIKNEINMYIKELGTEGHLIRLQVSELITDMEQEAALFVK
DYVKEKIKDPFVLLKQLQDMSSFELLDDAILLKLLGYSATTNMEEYVFPRGYRLLHKIPRLPMPIVENVVEAFGHLKLII
EADVKDLDEVEGIGAVRAQKIKKGLKRLQEKHYTDRQL

Nucleotide

• Length: 1077 bp

>NTDB_id=450367 I6G80_RS02635 WP_003178277.1 436689..437765(-) (disA) [Bacillus licheniformis strain FDAARGOS_923]
ATGGACAAAGACAAAAAAGGAGCGAAACAGGATCTTTCAGAAATATTGCAGTTTGTCGCCCCCGGCACGCCTCTTCGCGA
AGGAATCGAAAACGTCCTTCGGGCCAAAACAGGCGGATTAATCGTGGTCGGCTTCAACGATAAAGTGAAAGAAGTGGTTG
ACGGAGGGTTCCACATAAATTCTTCTTTCTCTCCGGCTCATCTGTACGAGCTGGCTAAAATGGACGGGGCGATCATTCTC
AGCGATTCAGGGCAAAAAATTCTATATGCCAATACACAGCTCATGCCTGAGGCGACGATTCCCTCCTCTGAGACGGGCAT
GAGACACAGAACAGCCGAGCGTGTGGCCAAGCAGACCGGCTGTCTGATCATCGCGATTTCTGAAAGACGGAATGTGATTA
CGCTCTATCAGGAAAATATGAAATATATACTCAAAGATATCGGCTTTATCTTAACAAAAGCCAATCAGGCGATTCAGACG
CTCGAAAAATACAAACTCATTTTGGACCATGCGATTTCCAATTTGAACGCGCTGGAATTTGAAGAGCTTGTTACATTTGG
GGATGTCATCTCCGTTCTGCATCGATATGAAATGGTGCTCAGAATCAAAAACGAAATTAATATGTATATTAAAGAGCTTG
GAACAGAAGGCCATCTCATCAGACTCCAGGTTAGCGAACTGATCACCGATATGGAGCAGGAAGCGGCGCTGTTCGTCAAA
GATTATGTGAAAGAAAAAATCAAAGACCCGTTTGTTCTGCTGAAACAGCTTCAGGATATGTCGAGTTTCGAATTGCTGGA
TGATGCGATTCTCCTTAAGCTTTTAGGCTATTCAGCAACTACGAACATGGAAGAATACGTTTTTCCGAGAGGCTACAGGC
TTCTCCACAAAATTCCCCGCCTCCCGATGCCGATCGTCGAAAATGTTGTCGAAGCATTCGGCCATTTAAAGCTCATTATC
GAAGCGGATGTAAAAGATTTGGATGAAGTGGAAGGAATTGGGGCTGTTCGTGCCCAAAAGATAAAGAAAGGGTTAAAGAG
ACTTCAGGAGAAACATTATACTGACAGGCAGCTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (27-139)

• DisA bacterial checkpoint controller linker region (DisA-linker) (144-282)

3D structure

• AlphaFold DB: Q65PD4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	86.111	100	0.866