Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ALEK_RS05525 Genome accession   NZ_CP054052
Coordinates   1126722..1128575 (-) Length   617 a.a.
NCBI ID   WP_071627254.1    Uniprot ID   -
Organism   Poseidonibacter lekithochrous strain DSM 100870     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1121722..1133575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ALEK_RS05510 (ALEK_1103) - 1124277..1125032 (+) 756 WP_071627251.1 competence/damage-inducible protein A -
  ALEK_RS05515 (ALEK_1104) - 1125035..1125700 (-) 666 WP_071627252.1 tetratricopeptide repeat protein -
  ALEK_RS05520 (ALEK_1105) - 1125697..1126719 (-) 1023 WP_071627253.1 alanine racemase -
  ALEK_RS05525 (ALEK_1106) uvrC 1126722..1128575 (-) 1854 WP_071627254.1 excinuclease ABC subunit UvrC Machinery gene
  ALEK_RS05530 (ALEK_1107) - 1128621..1129514 (-) 894 WP_071627255.1 hypothetical protein -
  ALEK_RS05535 (ALEK_1108) - 1129650..1130360 (+) 711 WP_071627256.1 SOS response-associated peptidase -
  ALEK_RS05540 (ALEK_1109) - 1130361..1131119 (-) 759 WP_071627257.1 choline/ethanolamine kinase family protein -
  ALEK_RS05545 (ALEK_1110) pnuC 1131100..1131714 (-) 615 WP_306341349.1 nicotinamide riboside transporter PnuC -
  ALEK_RS05550 (ALEK_1111) - 1131762..1132244 (-) 483 WP_071627310.1 glutathione peroxidase -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 71756.98 Da        Isoelectric Point: 8.7616

>NTDB_id=450338 ALEK_RS05525 WP_071627254.1 1126722..1128575(-) (uvrC) [Poseidonibacter lekithochrous strain DSM 100870]
MNLEEKLKQLPNEAGVYQYFDKDGHLLYIGKAKVLKNRVKSYFKFTPKLLPADKLGPRIYKMISEAVSLEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIMVDYAELFPRLEITRKVHKRKSIKYFGPYSTGAKDMLDSIYEIVPLVQKKSC
IKGKEACLFHQIKKCHAPCEGKITTEDYSKLVDTALDFIYNKTKLIAKLQEKMEEYAEDFRFEEAMKLRDRIKTIEKSQI
KSGMDLATNEDLDLFAIKAGRKKAVIVRMFIRDGKLASSSHDFIKIDTIIDNEPTIDLNEAYQRAIINYYDNEIPLLPKE
ILVANEVEEKEDLEVFIKERFDRNIKIINPKRDKKKTLVDIALNNCDELLRIESSKNQTTIYEELQNLFGLNTLPYRVES
YDNSHMMGQATVGAMVVWNEELNTFDKKAFRHYNLESKDEYSQMREMLMRRVDSFEKNPAPDLWVIDGGETLLKLAYDIV
QSVGVNLDIIAIAKEKVDAKAHRAKGAAKDIVHYKDKDGSIRALKLKTSDQRLQFVQRQRDEAHRFVINFHKKQKRAEDK
QISLLQIKGIGEAKVKKLLLYFGEFEKIKTASVEELKEVLNQKDAEVISSYFKENED

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=450338 ALEK_RS05525 WP_071627254.1 1126722..1128575(-) (uvrC) [Poseidonibacter lekithochrous strain DSM 100870]
ATGAATTTAGAAGAGAAATTAAAACAACTCCCAAATGAAGCGGGAGTCTATCAGTACTTTGACAAAGATGGTCATTTACT
TTATATTGGAAAAGCAAAAGTCCTTAAAAATAGAGTAAAGTCATACTTTAAATTTACTCCAAAACTATTACCAGCAGATA
AATTAGGTCCTAGAATATACAAGATGATTAGCGAAGCTGTATCACTTGAATGGATTGTTGTTCCTAATGAACATGATGCT
TTGATTTTGGAAAATTCTCTTATCAAACAACTAAAACCAAAATACAATATTTTACTACGAGATGATAAAACATATCCATA
TATCATGGTAGATTATGCAGAACTATTCCCTAGACTTGAAATCACTAGAAAAGTACATAAAAGAAAAAGTATCAAATACT
TTGGACCATACTCAACAGGGGCTAAAGATATGTTGGATTCTATTTATGAAATAGTTCCTCTAGTTCAAAAAAAATCATGT
ATCAAAGGAAAAGAAGCTTGTCTTTTCCATCAAATCAAAAAATGTCATGCTCCATGTGAAGGTAAGATTACTACAGAAGA
TTACTCAAAACTAGTAGATACTGCATTAGATTTTATATATAACAAAACAAAACTAATAGCAAAACTACAAGAAAAAATGG
AAGAGTATGCAGAAGACTTTAGATTTGAAGAAGCTATGAAATTAAGAGATAGAATAAAAACTATTGAAAAATCTCAAATC
AAATCAGGTATGGATTTAGCAACAAATGAAGACTTAGACCTTTTTGCAATTAAAGCAGGTAGAAAAAAAGCTGTAATTGT
AAGAATGTTCATTAGAGATGGAAAACTAGCTTCTTCATCACATGACTTTATTAAAATAGATACAATCATTGATAATGAAC
CTACAATAGATTTAAATGAAGCATATCAAAGAGCTATTATAAACTACTATGATAATGAAATTCCCCTACTTCCAAAAGAG
ATATTAGTAGCTAACGAAGTAGAAGAAAAAGAAGATTTAGAGGTATTTATAAAAGAGAGATTTGATAGAAATATCAAAAT
TATAAATCCAAAAAGAGATAAGAAAAAAACTCTAGTGGATATTGCACTTAATAACTGTGATGAATTACTTAGAATTGAAT
CTTCTAAAAATCAAACAACTATATATGAAGAACTGCAAAATCTATTTGGATTGAATACACTTCCTTATAGGGTTGAGTCT
TATGATAACTCACATATGATGGGACAAGCAACTGTTGGAGCTATGGTTGTATGGAATGAAGAGTTAAATACCTTTGATAA
AAAAGCTTTTAGACACTATAATCTTGAATCAAAGGACGAATACTCTCAAATGAGAGAAATGTTAATGAGAAGAGTTGATT
CTTTTGAAAAGAATCCTGCTCCAGACCTTTGGGTAATTGACGGAGGAGAGACACTACTAAAACTAGCATATGATATTGTT
CAATCAGTGGGAGTGAATCTAGATATAATAGCAATAGCAAAAGAAAAAGTAGATGCCAAAGCTCATAGAGCAAAAGGTGC
TGCAAAAGATATTGTTCATTATAAAGATAAAGATGGAAGTATTAGAGCTCTAAAACTTAAAACATCTGATCAAAGATTAC
AGTTTGTTCAAAGACAAAGAGATGAAGCACATAGATTTGTAATTAATTTCCATAAAAAACAAAAACGAGCAGAAGACAAA
CAAATATCTCTACTTCAAATCAAAGGTATTGGAGAAGCAAAAGTAAAAAAACTTCTTTTATATTTTGGTGAATTTGAAAA
AATAAAAACAGCATCAGTTGAGGAACTAAAAGAAGTTCTAAACCAAAAAGATGCAGAAGTAATATCTAGTTATTTTAAAG
AAAATGAGGACTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(14-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(386-548)

UvrB/uvrC motif (UVR)

(204-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.331

97.893

0.493