Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   FOC73_RS06835 Genome accession   NZ_CP053998
Coordinates   1400808..1402337 (+) Length   509 a.a.
NCBI ID   WP_002883784.1    Uniprot ID   A0A1V0GG48
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1395808..1407337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS06810 (FOC73_06810) - 1396274..1396945 (-) 672 WP_002883759.1 TrkA family potassium uptake protein -
  FOC73_RS06815 (FOC73_06815) - 1396985..1398349 (-) 1365 WP_002883736.1 TrkH family potassium uptake protein -
  FOC73_RS06820 (FOC73_06820) rsmG 1398418..1399131 (-) 714 WP_002883809.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FOC73_RS06825 (FOC73_06825) - 1399430..1399966 (+) 537 WP_002883813.1 YceD family protein -
  FOC73_RS06830 (FOC73_06830) covR 1400122..1400811 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  FOC73_RS06835 (FOC73_06835) covS 1400808..1402337 (+) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  FOC73_RS06840 (FOC73_06840) nrdR 1402459..1402938 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  FOC73_RS06845 (FOC73_06845) - 1402935..1404110 (+) 1176 WP_002883810.1 DnaD domain protein -
  FOC73_RS06850 (FOC73_06850) dnaI 1404114..1405016 (+) 903 WP_002883792.1 primosomal protein DnaI -
  FOC73_RS06855 (FOC73_06855) der 1405122..1406432 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  FOC73_RS06860 (FOC73_06860) - 1406496..1407125 (+) 630 WP_002883768.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58071.44 Da        Isoelectric Point: 5.1853

>NTDB_id=449962 FOC73_RS06835 WP_002883784.1 1400808..1402337(+) (covS) [Streptococcus salivarius strain FDAARGOS_771]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=449962 FOC73_RS06835 WP_002883784.1 1400808..1402337(+) (covS) [Streptococcus salivarius strain FDAARGOS_771]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCCAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCGAAAAATATCTATGCATCGATCATTAATGGTGTGCTTTCCGAAAAGCACTCTTTGGATGGTCA
AGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGACTCGCCTCCAGGTATGTCCGAGGTAAACAAACTGAAGTCAGTTTCCTATAAAGGGAAGCGTGGTTTC
TTGTTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAAATTTTCCATGATTTGGAATTCTA
TTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCGGTTATTAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTTGAGAGTTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

100

100

1