Detailed information NTG0449933

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FOC73_RS03635
• Genome accession: NZ_CP053998
• Coordinates: 787159..788235 (-)
• Length: 358 a.a.
• NCBI ID: WP_002884703.1
• Uniprot ID: A0A1W5ZBL0
• Organism: Streptococcus salivarius strain FDAARGOS_771
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 782159..793235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC73_RS03610 (FOC73_03610)	-	782903..783223 (+)	321	WP_002884714.1	hypothetical protein	-
FOC73_RS03615 (FOC73_03615)	-	783272..785338 (-)	2067	WP_002884214.1	cation:proton antiporter	-
FOC73_RS03620 (FOC73_03620)	-	785347..785589 (-)	243	WP_002884312.1	hypothetical protein	-
FOC73_RS03625 (FOC73_03625)	-	785586..786134 (-)	549	WP_002884470.1	class I SAM-dependent methyltransferase	-
FOC73_RS03630 (FOC73_03630)	-	786131..787075 (-)	945	WP_002884658.1	TIGR01212 family radical SAM protein	-
FOC73_RS03635 (FOC73_03635)	sepM	787159..788235 (-)	1077	WP_002884703.1	SepM family pheromone-processing serine protease	Regulator
FOC73_RS03640 (FOC73_03640)	coaD	788213..788710 (-)	498	WP_002884417.1	pantetheine-phosphate adenylyltransferase	-
FOC73_RS03645 (FOC73_03645)	rsmD	788743..789291 (-)	549	WP_231910681.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FOC73_RS03650 (FOC73_03650)	trxB	789432..790352 (-)	921	WP_002884706.1	thioredoxin-disulfide reductase	-
FOC73_RS03655 (FOC73_03655)	-	790418..790642 (-)	225	WP_002884393.1	DUF4059 family protein	-
FOC73_RS03660 (FOC73_03660)	-	790854..791597 (-)	744	WP_002884313.1	amino acid ABC transporter ATP-binding protein	-
FOC73_RS03665 (FOC73_03665)	-	791597..792343 (-)	747	WP_100066250.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 38988.67 Da
• Isoelectric Point: 9.2472

>NTDB_id=449933 FOC73_RS03635 WP_002884703.1 787159..788235(-) (sepM) [Streptococcus salivarius strain FDAARGOS_771]
MANKNESKSLLGKIWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVDKKADDSKGSYNFVAVAQTKAT
LALMLYAQLNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAIYQGLTLAGKEASLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSADLIKYVQGLKLGSKVKVTYTTDDKEKTATGKIIKIANGKNGIGIGLTDHTEVKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGSVGDIGGAYLKVKSAADSGADIFFVPNNPVTKEMKKADPD
AKTNYQEAKEAAKKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=449933 FOC73_RS03635 WP_002884703.1 787159..788235(-) (sepM) [Streptococcus salivarius strain FDAARGOS_771]
GTGGCAAACAAGAACGAATCTAAATCACTATTAGGGAAAATTTGGCGGATTAAGTGGTGGTTGTTAAGTATTTTTACGGT
ACTTTTCCTCCTATTTGCCCTCTTTTTTCCGCTAAATAATTATTATGTTGAGCTTCCGGGTGGTGCTTTTGATACTAAGG
AAGTCTTGACTGTAGATAAGAAAGCTGATGATTCAAAAGGATCCTACAATTTTGTGGCGGTGGCCCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATGCTCAGCTTAATGATTTTGCAAAGCTTCAAACAGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGTATCAACCAATTTTACATGGAGACTTCCCAAAACCAAGCGATTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGCTAGCTTGGAGTATATGGGTGTTTATGTGCTTCAGGTGGCTGATGATTCTAGCTTCAAGGGTGTCCTTAAT
ATTGCGGATACGGTGACAGCTGTCAATGGCAAGACTTTTGATAACTCTGCTGATTTGATAAAATACGTTCAAGGTCTTAA
GCTGGGTTCAAAAGTCAAGGTCACTTATACGACAGATGACAAAGAAAAGACTGCTACTGGTAAGATTATCAAGATTGCCA
ATGGTAAAAATGGTATTGGTATCGGTTTGACAGATCATACCGAGGTCAAGAGTCCTGAAAATGTGAAGTTTAAACTTGAT
GGTGTTGGTGGACCAAGTGCGGGTCTTATGTTTACCCTAGCTATTTACGATCAGGTGTCTGGTCAAGATCTCAAGGCTGG
TCGTAAGATTGCTGGAACAGGAACCATTGAAAAGGATGGTTCTGTCGGTGATATCGGTGGTGCCTACCTTAAGGTGAAAT
CAGCGGCTGATAGTGGTGCAGACATTTTCTTTGTACCAAATAATCCAGTAACCAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAACTATCAAGAGGCCAAGGAAGCTGCTAAGAAACTGGGAACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCTATTGATTATTTGAAAAAGACTAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (142-206)

3D structure

• AlphaFold DB: A0A1W5ZBL0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	65.396	95.251	0.623