Detailed information    

insolico Bioinformatically predicted

Overview


Name   sinR   Type   Regulator
Locus tag   FOC75_RS04590 Genome accession   NZ_CP053991
Coordinates   796588..796911 (-) Length   107 a.a.
NCBI ID   WP_000578878.1    Uniprot ID   A0A6L7H7A6
Organism   Bacillus cereus strain FDAARGOS_781     
Function   repression of rok; repression of degU; repression of spo0A (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 770254..799856 796588..796911 within 0


Gene organization within MGE regions


Location: 770254..799856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC75_RS04385 (FOC75_04385) - 770254..770463 (+) 210 WP_000428510.1 helix-turn-helix transcriptional regulator -
  FOC75_RS04390 (FOC75_04390) - 770466..770843 (+) 378 WP_001109905.1 hypothetical protein -
  FOC75_RS04395 (FOC75_04395) - 770872..771054 (+) 183 WP_001178301.1 DUF3976 domain-containing protein -
  FOC75_RS04400 (FOC75_04400) - 771189..771545 (+) 357 WP_001036567.1 hypothetical protein -
  FOC75_RS04405 (FOC75_04405) - 771564..771833 (+) 270 WP_001195372.1 hypothetical protein -
  FOC75_RS29565 (FOC75_04410) - 771977..772318 (+) 342 Protein_768 hypothetical protein -
  FOC75_RS04415 (FOC75_04415) - 772312..773055 (+) 744 Protein_769 WXG100 family type VII secretion target -
  FOC75_RS04420 (FOC75_04420) - 773073..773264 (+) 192 WP_001182254.1 hypothetical protein -
  FOC75_RS04425 (FOC75_04425) - 773293..773541 (+) 249 WP_000771628.1 DUF4176 domain-containing protein -
  FOC75_RS04430 (FOC75_04430) - 773582..773770 (+) 189 WP_000516413.1 hypothetical protein -
  FOC75_RS04435 (FOC75_04435) - 774417..774878 (-) 462 WP_000605456.1 hypothetical protein -
  FOC75_RS04440 (FOC75_04440) - 775031..775615 (-) 585 WP_001086694.1 hypothetical protein -
  FOC75_RS04445 (FOC75_04445) - 775701..776045 (-) 345 WP_000164232.1 hypothetical protein -
  FOC75_RS04450 (FOC75_04450) - 776127..776906 (-) 780 WP_000191135.1 hypothetical protein -
  FOC75_RS04455 (FOC75_04455) - 777013..777330 (-) 318 WP_002035977.1 BRO family protein -
  FOC75_RS04460 (FOC75_04460) - 777509..777712 (-) 204 WP_000977940.1 hypothetical protein -
  FOC75_RS04465 (FOC75_04465) - 777696..777899 (-) 204 WP_000511673.1 hypothetical protein -
  FOC75_RS04470 (FOC75_04470) - 778091..778339 (-) 249 WP_001000828.1 hypothetical protein -
  FOC75_RS04475 (FOC75_04475) - 778515..778835 (-) 321 WP_000230742.1 hypothetical protein -
  FOC75_RS04480 (FOC75_04480) - 778825..779064 (-) 240 WP_000828804.1 hypothetical protein -
  FOC75_RS04485 (FOC75_04485) - 779201..780526 (-) 1326 WP_001058016.1 hypothetical protein -
  FOC75_RS04490 (FOC75_04490) - 781189..781335 (+) 147 WP_162484064.1 hypothetical protein -
  FOC75_RS04495 (FOC75_04495) - 781372..781521 (+) 150 WP_157404510.1 hypothetical protein -
  FOC75_RS04500 (FOC75_04500) - 781595..781939 (+) 345 WP_157404511.1 HNH endonuclease -
  FOC75_RS04505 (FOC75_04505) - 782079..782519 (+) 441 WP_001153942.1 phage terminase small subunit P27 family -
  FOC75_RS04510 (FOC75_04510) - 782516..782776 (+) 261 WP_000811159.1 hypothetical protein -
  FOC75_RS04515 (FOC75_04515) - 782951..783196 (+) 246 WP_000874865.1 hypothetical protein -
  FOC75_RS04520 (FOC75_04520) - 783487..784788 (+) 1302 WP_000896384.1 phage portal protein -
  FOC75_RS04525 (FOC75_04525) - 784781..786517 (+) 1737 WP_001003089.1 phage major capsid protein -
  FOC75_RS04530 (FOC75_04530) - 786825..787319 (-) 495 WP_000093742.1 hypothetical protein -
  FOC75_RS04535 (FOC75_04535) - 787461..788198 (-) 738 WP_000334962.1 hypothetical protein -
  FOC75_RS04540 (FOC75_04540) - 788322..789407 (-) 1086 WP_000060403.1 tyrosine-type recombinase/integrase -
  FOC75_RS04550 (FOC75_04550) - 789790..790014 (-) 225 WP_000090210.1 hypothetical protein -
  FOC75_RS04555 (FOC75_04555) - 790292..791047 (-) 756 WP_000858633.1 class I SAM-dependent methyltransferase -
  FOC75_RS04560 (FOC75_04560) - 791413..791640 (+) 228 WP_000251855.1 hypothetical protein -
  FOC75_RS04565 (FOC75_04565) - 791796..793082 (+) 1287 WP_000247011.1 D-alanyl-D-alanine carboxypeptidase family protein -
  FOC75_RS04570 (FOC75_04570) sipW 793274..793843 (+) 570 WP_000767813.1 signal peptidase I SipW -
  FOC75_RS04575 (FOC75_04575) - 793906..794493 (+) 588 WP_000172840.1 CalY family protein -
  FOC75_RS04580 (FOC75_04580) - 794655..795521 (+) 867 WP_000917469.1 DUF4047 domain-containing protein -
  FOC75_RS04585 (FOC75_04585) calY 795919..796512 (+) 594 WP_000053731.1 biofilm matrix protein CalY -
  FOC75_RS04590 (FOC75_04590) sinR 796588..796911 (-) 324 WP_000578878.1 helix-turn-helix domain-containing protein Regulator
  FOC75_RS04595 (FOC75_04595) - 796991..797125 (-) 135 WP_000276214.1 anti-repressor SinI family protein -
  FOC75_RS04600 (FOC75_04600) inhA1 797469..799856 (+) 2388 WP_001035926.1 M6 family metalloprotease immune inhibitor InhA1 -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 12319.17 Da        Isoelectric Point: 9.6244

>NTDB_id=449830 FOC75_RS04590 WP_000578878.1 796588..796911(-) (sinR) [Bacillus cereus strain FDAARGOS_781]
MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNLQKNPSIQFLEKIAAVLQIPVDTLLHDETTKEANLDSEWTQLV
KDAMNSGVSKEQFREFLEFTKWKQNQK

Nucleotide


Download         Length: 324 bp        

>NTDB_id=449830 FOC75_RS04590 WP_000578878.1 796588..796911(-) (sinR) [Bacillus cereus strain FDAARGOS_781]
ATGATTGGAGAACGTATAAAACGCCTTCGTTTACAAAAAGGTATTTCATTAACTGAACTTGCCGAAAAAGCTGGCGTTGC
TAAATCTTACATTAGTTCTATAGAACGAAATTTACAAAAGAACCCTTCCATTCAGTTTCTTGAAAAGATCGCAGCAGTTC
TACAAATTCCAGTTGATACTTTACTTCATGATGAAACAACAAAGGAAGCTAACCTAGACTCCGAATGGACACAGCTCGTC
AAAGATGCAATGAACTCTGGTGTCTCCAAAGAACAATTTCGTGAATTTCTTGAATTTACAAAATGGAAGCAAAATCAAAA
ATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A6L7H7A6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sinR Bacillus subtilis subsp. subtilis str. 168

67.89

100

0.692