Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   STT55_RS08935 Genome accession   NZ_CP065502
Coordinates   1718252..1718545 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain ST55     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1713252..1723545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT55_RS08900 (STT55_08830) - 1713654..1714097 (-) 444 WP_002946118.1 hypothetical protein -
  STT55_RS08905 - 1714171..1714509 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  STT55_RS08910 (STT55_08840) - 1714840..1715037 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  STT55_RS08915 (STT55_08845) - 1715286..1716479 (-) 1194 WP_022096898.1 acetate kinase -
  STT55_RS08920 (STT55_08850) comGH 1716535..1717491 (-) 957 WP_173940669.1 class I SAM-dependent methyltransferase Machinery gene
  STT55_RS08925 (STT55_08855) comGG 1717536..1717853 (-) 318 WP_141326604.1 competence type IV pilus minor pilin ComGG Machinery gene
  STT55_RS08930 (STT55_08860) comGF 1717831..1718268 (-) 438 WP_022096897.1 competence type IV pilus minor pilin ComGF Machinery gene
  STT55_RS08935 (STT55_08865) comGE 1718252..1718545 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  STT55_RS08940 (STT55_08870) comGD 1718517..1718945 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  STT55_RS08945 (STT55_08875) comGC 1718905..1719231 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STT55_RS08950 (STT55_08880) comGB 1719228..1720328 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  STT55_RS08955 (STT55_08885) comGA/cglA/cilD 1720210..1721151 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  STT55_RS08960 (STT55_08890) - 1721232..1721594 (-) 363 WP_173940670.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=449611 STT55_RS08935 WP_011226625.1 1718252..1718545(-) (comGE) [Streptococcus thermophilus strain ST55]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=449611 STT55_RS08935 WP_011226625.1 1718252..1718545(-) (comGE) [Streptococcus thermophilus strain ST55]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361