Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   STT128_RS08035 Genome accession   NZ_CP065500
Coordinates   1553222..1553953 (+) Length   243 a.a.
NCBI ID   WP_002948869.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST128     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1548222..1558953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT128_RS08000 (STT128_08085) - 1548373..1549943 (+) 1571 WP_347230068.1 IS3-like element ISSth1b family transposase -
  STT128_RS08005 (STT128_08090) - 1550089..1550328 (-) 240 WP_347230069.1 Blp family class II bacteriocin -
  STT128_RS08010 - 1550579..1550980 (-) 402 WP_347230070.1 hypothetical protein -
  STT128_RS08015 (STT128_08095) - 1551835..1551978 (-) 144 WP_014608661.1 hypothetical protein -
  STT128_RS08020 (STT128_08100) - 1551985..1552215 (-) 231 WP_014608662.1 bacteriocin class II family protein -
  STT128_RS08025 (STT128_08105) - 1552571..1552771 (-) 201 WP_011681569.1 hypothetical protein -
  STT128_RS08030 (STT128_08110) - 1552790..1552966 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  STT128_RS08035 (STT128_08115) comE/blpR 1553222..1553953 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  STT128_RS08040 - 1554490..1555293 (+) 804 WP_224102945.1 ATP-binding protein -
  STT128_RS08045 (STT128_08125) - 1555311..1555472 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  STT128_RS08050 (STT128_08130) - 1555487..1556854 (-) 1368 Protein_1533 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27803.11 Da        Isoelectric Point: 6.9136

>NTDB_id=449487 STT128_RS08035 WP_002948869.1 1553222..1553953(+) (comE/blpR) [Streptococcus thermophilus strain ST128]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=449487 STT128_RS08035 WP_002948869.1 1553222..1553953(+) (comE/blpR) [Streptococcus thermophilus strain ST128]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362