Detailed information NTG0449483

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: STT128_RS07675
• Genome accession: NZ_CP065500
• Coordinates: 1483128..1485233 (-)
• Length: 701 a.a.
• NCBI ID: WP_347230063.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST128
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1478128..1490233

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT128_RS07640 (STT128_07730)	pptB	1478589..1479626 (-)	1038	WP_087010122.1	ABC transporter permease	Regulator
STT128_RS07645 (STT128_07735)	pptA	1479623..1480354 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
STT128_RS07650 (STT128_07740)	-	1480419..1480838 (+)	420	WP_347230062.1	HIT family protein	-
STT128_RS07655 (STT128_07745)	-	1480835..1481143 (+)	309	WP_014608635.1	hypothetical protein	-
STT128_RS07660 (STT128_07750)	-	1481185..1481916 (-)	732	WP_014608636.1	hypothetical protein	-
STT128_RS07665 (STT128_07755)	-	1481935..1482570 (-)	636	WP_014727665.1	DUF4230 domain-containing protein	-
STT128_RS07670	-	1482589..1482714 (-)	126	WP_011681534.1	hypothetical protein	-
STT128_RS07675 (STT128_07760)	clpE	1483128..1485233 (-)	2106	WP_347230063.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
STT128_RS07680 (STT128_07765)	-	1485968..1488967 (-)	3000	WP_347230064.1	DEAD/DEAH box helicase family protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77330.19 Da
• Isoelectric Point: 4.7951

>NTDB_id=449483 STT128_RS07675 WP_347230063.1 1483128..1485233(-) (clpE) [Streptococcus thermophilus strain ST128]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQQGNGPKQDGILAKLGRN
LTQEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQH
PVTDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEA
AKAYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2106 bp

>NTDB_id=449483 STT128_RS07675 WP_347230063.1 1483128..1485233(-) (clpE) [Streptococcus thermophilus strain ST128]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACAGGGTAACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAAC
TTGACTCAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCAC
AAGCCATCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AATGCTGCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACAT
CCAGTAACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGG
TGACTGCGACTGTAAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGAT
ATCGAACGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TTCCATCCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATAC
CTTGACAGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCA
CCCTTCTCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATT
ATCGCAACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTT
GAAACCTTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTT
CTAAGATTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

• AAA lid domain (AAA_lid_9) (257-351)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.648	100	0.466
clpC	Lactococcus lactis subsp. cremoris KW2	49.002	92.867	0.455
clpE	Streptococcus pneumoniae D39	48.131	91.583	0.441
clpE	Streptococcus pneumoniae R6	48.131	91.583	0.441
clpE	Streptococcus pneumoniae TIGR4	48.131	91.583	0.441
clpE	Streptococcus pneumoniae Rx1	48.131	91.583	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	45.414	94.864	0.431
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.178	93.01	0.392
clpC	Streptococcus thermophilus LMD-9	44.084	88.017	0.388
clpC	Streptococcus thermophilus LMG 18311	43.922	88.017	0.387
clpC	Streptococcus pneumoniae Rx1	43.339	88.873	0.385
clpC	Streptococcus pneumoniae D39	43.339	88.873	0.385
clpC	Streptococcus pneumoniae TIGR4	43.339	88.873	0.385
clpC	Streptococcus mutans UA159	42.995	88.588	0.381