Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   STAVA116_RS08255 Genome accession   NZ_CP065498
Coordinates   1599297..1599590 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain AVA116     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1594297..1604590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA116_RS08220 (STAVA116_08170) - 1594695..1595138 (-) 444 WP_087010195.1 CAAX protease -
  STAVA116_RS08225 - 1595212..1595637 (-) 426 WP_087010196.1 CPBP family intramembrane glutamic endopeptidase -
  STAVA116_RS08230 (STAVA116_08180) - 1595885..1596082 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  STAVA116_RS08235 (STAVA116_08185) - 1596331..1597524 (-) 1194 WP_087010197.1 acetate kinase -
  STAVA116_RS08240 (STAVA116_08190) comGH 1597580..1598536 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STAVA116_RS08245 (STAVA116_08195) comGG 1598581..1598898 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  STAVA116_RS08250 (STAVA116_08200) comGF 1598876..1599313 (-) 438 WP_022096897.1 competence type IV pilus minor pilin ComGF Machinery gene
  STAVA116_RS08255 (STAVA116_08205) comGE 1599297..1599590 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  STAVA116_RS08260 (STAVA116_08210) comGD 1599562..1599990 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  STAVA116_RS08265 (STAVA116_08215) comGC 1599950..1600276 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STAVA116_RS08270 (STAVA116_08220) comGB 1600273..1601373 (-) 1101 WP_157659050.1 competence type IV pilus assembly protein ComGB Machinery gene
  STAVA116_RS08275 (STAVA116_08225) comGA/cglA/cilD 1601255..1602196 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  STAVA116_RS08280 (STAVA116_08230) - 1602277..1602639 (-) 363 WP_087010198.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=449401 STAVA116_RS08255 WP_011226625.1 1599297..1599590(-) (comGE) [Streptococcus thermophilus strain AVA116]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=449401 STAVA116_RS08255 WP_011226625.1 1599297..1599590(-) (comGE) [Streptococcus thermophilus strain AVA116]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361