Detailed information
Bioinformatically predicted
Overview
| Name | clpE | Type | Regulator |
| Locus tag | ST4021_RS07635 | Genome accession | NZ_CP065493 |
| Coordinates | 1484293..1486392 (-) | Length | 699 a.a. |
| NCBI ID | WP_046206496.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain 4021 | ||
| Function | repress competence development (at the early growth phase) (predicted from homology) Competence regulation |
||
Genomic Context
Location: 1479293..1491392
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ST4021_RS07600 (ST4021_07640) | pptB | 1479752..1480789 (-) | 1038 | WP_046206495.1 | ABC transporter permease | Regulator |
| ST4021_RS07605 (ST4021_07645) | pptA | 1480786..1481517 (-) | 732 | WP_002951673.1 | ABC transporter ATP-binding protein | Regulator |
| ST4021_RS07610 (ST4021_07650) | - | 1481582..1482001 (+) | 420 | WP_011681530.1 | HIT family protein | - |
| ST4021_RS07615 (ST4021_07655) | - | 1481998..1482297 (+) | 300 | WP_011681531.1 | hypothetical protein | - |
| ST4021_RS07620 (ST4021_07660) | - | 1482349..1483026 (-) | 678 | WP_011681532.1 | hypothetical protein | - |
| ST4021_RS07625 (ST4021_07665) | - | 1483096..1483731 (-) | 636 | WP_011681533.1 | DUF4230 domain-containing protein | - |
| ST4021_RS07630 | - | 1483750..1483875 (-) | 126 | WP_011681534.1 | hypothetical protein | - |
| ST4021_RS07635 (ST4021_07670) | clpE | 1484293..1486392 (-) | 2100 | WP_046206496.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| ST4021_RS07640 (ST4021_07675) | - | 1487106..1488197 (-) | 1092 | WP_046206497.1 | nucleotidyltransferase | - |
| ST4021_RS07645 (ST4021_07680) | - | 1488204..1488944 (-) | 741 | WP_277426406.1 | class I SAM-dependent methyltransferase | - |
| ST4021_RS07650 (ST4021_07685) | rsfS | 1489269..1489622 (-) | 354 | WP_011227491.1 | ribosome silencing factor | - |
| ST4021_RS07655 (ST4021_07690) | yqeK | 1489646..1490236 (-) | 591 | WP_002951696.1 | bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK | - |
| ST4021_RS07660 (ST4021_07695) | - | 1490233..1490865 (-) | 633 | WP_002951698.1 | nicotinate-nucleotide adenylyltransferase | - |
| ST4021_RS07665 (ST4021_07700) | yhbY | 1490969..1491286 (-) | 318 | WP_002951701.1 | ribosome assembly RNA-binding protein YhbY | - |
Sequence
Protein
Download Length: 699 a.a. Molecular weight: 77228.16 Da Isoelectric Point: 4.8280
>NTDB_id=449068 ST4021_RS07635 WP_046206496.1 1484293..1486392(-) (clpE) [Streptococcus thermophilus strain 4021]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEVAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGASDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEVAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGASDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK
Nucleotide
Download Length: 2100 bp
>NTDB_id=449068 ST4021_RS07635 WP_046206496.1 1484293..1486392(-) (clpE) [Streptococcus thermophilus strain 4021]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGTTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCATCGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGTTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCATCGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpE | Streptococcus mutans UA159 |
47.429 |
100 |
0.475 |
| clpC | Lactococcus lactis subsp. cremoris KW2 |
49.219 |
91.559 |
0.451 |
| clpE | Streptococcus pneumoniae D39 |
48.657 |
90.558 |
0.441 |
| clpE | Streptococcus pneumoniae R6 |
48.657 |
90.558 |
0.441 |
| clpE | Streptococcus pneumoniae Rx1 |
48.657 |
90.558 |
0.441 |
| clpE | Streptococcus pneumoniae TIGR4 |
48.657 |
90.558 |
0.441 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
45.82 |
92.418 |
0.423 |
| clpC | Streptococcus thermophilus LMD-9 |
43.058 |
91.702 |
0.395 |
| clpC | Streptococcus thermophilus LMG 18311 |
43.103 |
91.273 |
0.393 |
| clpC | Streptococcus pneumoniae TIGR4 |
43.339 |
89.127 |
0.386 |
| clpC | Streptococcus pneumoniae Rx1 |
43.339 |
89.127 |
0.386 |
| clpC | Streptococcus pneumoniae D39 |
43.339 |
89.127 |
0.386 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
43.598 |
88.269 |
0.385 |
| clpC | Streptococcus mutans UA159 |
43.156 |
88.841 |
0.383 |