Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   ST4145_RS08105 Genome accession   NZ_CP065492
Coordinates   1580918..1583743 (-) Length   941 a.a.
NCBI ID   WP_011681621.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4145     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1575918..1588743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4145_RS08065 (ST4145_07995) efp 1576190..1576750 (-) 561 WP_011227545.1 elongation factor P -
  ST4145_RS08070 (ST4145_08000) - 1576863..1577318 (-) 456 WP_002951893.1 deaminase -
  ST4145_RS08075 (ST4145_08005) - 1577337..1578398 (-) 1062 WP_011681620.1 Xaa-Pro peptidase family protein -
  ST4145_RS08080 (ST4145_08010) - 1578587..1579015 (-) 429 WP_002951896.1 hypothetical protein -
  ST4145_RS08085 (ST4145_08015) - 1579060..1579620 (-) 561 WP_014608689.1 ABC transporter ATP-binding protein -
  ST4145_RS08090 (ST4145_08020) - 1579622..1580011 (-) 390 WP_014608690.1 ATP-binding cassette domain-containing protein -
  ST4145_RS08095 (ST4145_08025) - 1580199..1580390 (-) 192 WP_014727693.1 hypothetical protein -
  ST4145_RS08100 (ST4145_08030) - 1580552..1580824 (-) 273 WP_002946573.1 DUF3923 family protein -
  ST4145_RS08105 (ST4145_08035) uvrA 1580918..1583743 (-) 2826 WP_011681621.1 excinuclease ABC subunit UvrA Machinery gene
  ST4145_RS08110 (ST4145_08040) - 1584052..1584996 (+) 945 WP_002951901.1 magnesium transporter CorA family protein -
  ST4145_RS08115 (ST4145_08045) - 1585067..1585738 (+) 672 WP_011681622.1 DUF1129 domain-containing protein -
  ST4145_RS08120 (ST4145_08050) - 1585855..1586736 (+) 882 WP_011681623.1 DUF4300 family protein -
  ST4145_RS08125 (ST4145_08055) rpsR 1586863..1587102 (-) 240 WP_002945024.1 30S ribosomal protein S18 -
  ST4145_RS08130 (ST4145_08060) ssb 1587144..1587662 (-) 519 WP_002951905.1 single-stranded DNA-binding protein Machinery gene
  ST4145_RS08135 (ST4145_08065) rpsF 1587674..1587964 (-) 291 WP_011681624.1 30S ribosomal protein S6 -

Sequence

Protein


Download         Length: 941 a.a.        Molecular weight: 103963.18 Da        Isoelectric Point: 6.0617

>NTDB_id=448974 ST4145_RS08105 WP_011681621.1 1580918..1583743(-) (uvrA) [Streptococcus thermophilus strain 4145]
MQDKLVIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGVPYCINGHGAIKSSSVEQIVDEVLALPERTRMQILAPIVRRRK
GQHKAIFERVQKDGYVRVRVDGEIYDVTEVPELSKSKMHNIEVVVDRLVNKEGIRSRLFDSVEAALRLADGYLIVDTMDD
NELLYSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGNKLEVDIDLVIPDPSKTLREGALAPWNPISSNYYPAML
EQAMEQFGVDMDTPFENLKKEEQDLILYGSGDREFHFHYVNDFGRVRDIDIPFEGVVTNINRRYHETNSDFTRNVMRGYM
NELSCPTCHGYRLNEAALSVRVGGEDGLNIGQISELSISDHLQEIDRLELGENEEMIARPIIKEIKDRLTFLNNVGLNYL
TLSRMAGTLSGGESQRIRLATQIGSNLSGVLYVLDEPSIGLHQRDNDRLISSLKKMRDLGNTLIVVEHDEDTMREADWLI
DVGPGAGAFGGQIIASGTPEAVARNKKSITGQYLSGAKSIPVPTERRVGNGCFIEVKGASENNLKNVSVKFPLGKLIAVT
GVSGSGKSTLVNSILKKKIAQELNRNSEKPGKHKSVTGIENIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGTRYNSETLEVRYKGKNIAEILDMTVDDAVDFF
AAIPKIARKVQTIKDVGLGYVTLGQSATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTDDIARLLKVLQRFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIVATGTPEEVVAVPKSYTGQYLKEKLK

Nucleotide


Download         Length: 2826 bp        

>NTDB_id=448974 ST4145_RS08105 WP_011681621.1 1580918..1583743(-) (uvrA) [Streptococcus thermophilus strain 4145]
ATGCAAGATAAGTTAGTGATTCGCGGAGCAAGAGCTCACAATTTAAAAAATATTGATGTAGAGATTCCTCGTGACAAGCT
CGTCGTCGTGACGGGGTTGTCGGGGTCTGGTAAGTCTTCTTTGGCTTTTGATACAATTTATGCAGAGGGTCAGCGCCGTT
ATGTTGAAAGTCTCTCAGCTTATGCCCGCCAATTCTTGGGAAATATGGAGAAACCTGATGTGGACTCGATTGATGGCTTG
AGTCCTGCCATCTCCATTGATCAGAAAACAACGAGTAAGAACCCTCGTTCGACTGTGGGAACTGTAACGGAGATTAATGA
CTATCTTCGTCTCCTTTATGCGCGTGTGGGTGTGCCTTATTGTATCAATGGGCATGGAGCCATTAAGTCGTCATCAGTGG
AACAGATTGTAGATGAGGTTTTAGCCCTTCCTGAACGGACACGTATGCAGATTTTAGCGCCGATTGTCCGTCGTCGAAAG
GGGCAACACAAGGCGATTTTTGAGCGCGTGCAGAAGGACGGTTATGTTCGTGTTCGTGTGGATGGTGAGATATACGATGT
GACGGAAGTCCCTGAGCTATCCAAGTCGAAGATGCATAATATTGAGGTGGTTGTGGACCGTTTGGTTAATAAGGAAGGTA
TCCGTAGTCGTCTCTTTGACTCAGTCGAGGCAGCGCTACGTTTAGCGGATGGCTACTTGATTGTGGATACTATGGATGAT
AATGAATTGCTCTACTCGGAGCATTATTCTTGTCCAGTTTGTGGTTTTACAGTGCCTGAGTTGGAGCCGCGTCTCTTTTC
CTTCAATGCGCCATTTGGTTCTTGTCCGACCTGTGACGGTTTAGGAAATAAACTAGAAGTTGATATTGATTTGGTCATTC
CTGACCCTAGTAAGACCTTGCGTGAAGGTGCACTAGCGCCTTGGAATCCTATCTCATCCAACTACTATCCTGCCATGCTT
GAGCAGGCCATGGAACAGTTTGGCGTGGATATGGATACGCCATTTGAAAATCTTAAAAAAGAAGAACAAGATTTGATTCT
CTACGGATCTGGTGACCGCGAGTTCCATTTCCATTATGTTAATGATTTTGGTAGGGTGCGTGATATTGACATTCCTTTTG
AAGGGGTTGTGACTAATATCAATCGACGCTATCATGAGACTAACAGTGATTTCACCCGCAATGTCATGCGTGGTTATATG
AATGAACTGTCATGTCCAACTTGTCATGGCTATCGTCTTAACGAAGCAGCACTCTCGGTTCGTGTTGGTGGTGAGGATGG
CTTAAATATTGGTCAAATTTCTGAGCTGTCTATTTCTGATCATCTTCAAGAAATAGATCGCCTTGAATTAGGTGAGAATG
AAGAAATGATTGCCCGTCCAATTATCAAGGAAATCAAGGATCGTCTGACTTTCTTAAACAATGTCGGCCTTAATTACTTG
ACTCTCTCTCGTATGGCCGGAACACTTTCAGGTGGTGAGAGTCAGCGTATCCGTTTGGCGACACAGATTGGCTCCAACCT
TTCTGGAGTCCTTTATGTTTTGGATGAGCCCTCTATAGGTCTTCATCAGCGTGATAATGATCGCTTGATTTCAAGTCTTA
AAAAGATGCGTGATTTGGGCAATACCTTAATTGTGGTGGAGCATGATGAAGATACCATGCGTGAAGCTGACTGGCTTATC
GATGTAGGACCTGGCGCCGGTGCCTTTGGTGGACAAATCATAGCTTCAGGAACCCCAGAAGCAGTTGCTAGAAATAAGAA
ATCAATTACTGGTCAGTACCTGTCAGGTGCTAAATCAATTCCTGTACCGACGGAACGCCGTGTAGGAAACGGCTGTTTTA
TCGAGGTTAAAGGAGCCAGTGAAAATAATCTTAAAAATGTGTCTGTCAAGTTCCCACTTGGAAAATTAATCGCAGTGACA
GGCGTTTCTGGTTCTGGAAAGTCAACTTTGGTTAACAGTATTCTCAAGAAAAAGATTGCCCAAGAGCTTAATCGAAACAG
TGAGAAACCTGGGAAACATAAATCGGTGACTGGAATCGAGAATATCGAGCGTTTGATTGATATTGATCAAAGTCCAATCG
GGCGTACTCCACGTTCCAACCCTGCAACCTACACAGGCGTCTTCGACGATATTCGCGATCTTTTTGCTCAAACCAATGAG
GCCAAGATTCGCGGTTATAAGAAGGGACGTTTCTCTTTCAATGTCAAAGGTGGCCGTTGTGAAGCCTGCTCTGGTGATGG
GATTATCAAGATTGAGATGCACTTCTTGCCTGATGTTTATGTACCTTGTGAGGTTTGCCATGGCACACGCTATAATTCTG
AGACCTTAGAAGTTCGTTATAAAGGGAAGAATATTGCTGAAATTCTGGATATGACAGTTGATGACGCGGTTGATTTCTTT
GCGGCTATCCCTAAGATTGCTCGTAAGGTGCAGACAATCAAGGATGTGGGGCTCGGGTATGTGACTTTGGGGCAATCAGC
AACAACCCTATCAGGTGGTGAGGCACAGCGTATGAAACTGGCTAGTGAACTTCACAAACGCTCTACTGGGAAGTCTTTCT
ACATTCTCGATGAGCCTACGACTGGTCTCCATACAGATGATATTGCTCGTCTCTTGAAGGTGCTTCAGCGTTTTGTGGAC
GATGGTAACACGGTTCTCGTGATTGAGCACAATCTGGATGTTATTAAGACAGCAGACCATATCATTGATTTGGGTCCTGA
AGGTGGTGTTGGTGGAGGTACTATCGTAGCTACAGGGACTCCAGAAGAGGTAGTAGCCGTTCCCAAAAGCTATACAGGAC
AATATTTGAAAGAAAAATTGAAATAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)

UvrA interaction domain (UvrA_inter)

(132-239)

ABC transporter (ABC_tran)

(624-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

85

99.894

0.849
  uvrA Streptococcus pneumoniae TIGR4

85

99.894

0.849
  uvrA Streptococcus pneumoniae D39

85

99.894

0.849