Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   HQ618_RS10725 Genome accession   NZ_CP053890
Coordinates   2111725..2112954 (+) Length   409 a.a.
NCBI ID   WP_000728357.1    Uniprot ID   A0AAD2WWM9
Organism   Streptococcus agalactiae strain GBS68     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2106725..2117954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ618_RS10700 (HQ618_10640) - 2107887..2110466 (+) 2580 WP_000154429.1 YfhO family protein -
  HQ618_RS10720 (HQ618_10660) rlmH 2111045..2111524 (-) 480 WP_000768333.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  HQ618_RS10725 (HQ618_10665) htrA 2111725..2112954 (+) 1230 WP_000728357.1 S1C family serine protease Regulator
  HQ618_RS10730 (HQ618_10670) spo0J 2113052..2113825 (+) 774 WP_000456084.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 43090.54 Da        Isoelectric Point: 9.5271

>NTDB_id=448718 HQ618_RS10725 WP_000728357.1 2111725..2112954(+) (htrA) [Streptococcus agalactiae strain GBS68]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=448718 HQ618_RS10725 WP_000728357.1 2111725..2112954(+) (htrA) [Streptococcus agalactiae strain GBS68]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGAGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCCGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAAGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

PDZ domain (PDZ_2)

(300-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

63.359

96.088

0.609
  htrA Streptococcus gordonii str. Challis substr. CH1

57.357

98.044

0.562
  htrA Streptococcus mitis NCTC 12261

56.533

97.311

0.55
  htrA Streptococcus pneumoniae TIGR4

55.037

99.511

0.548
  htrA Streptococcus pneumoniae Rx1

55.037

99.511

0.548
  htrA Streptococcus pneumoniae D39

55.037

99.511

0.548
  htrA Streptococcus pneumoniae R6

55.037

99.511

0.548