Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   HQ618_RS01135 Genome accession   NZ_CP053890
Coordinates   190768..191742 (+) Length   324 a.a.
NCBI ID   WP_001008574.1    Uniprot ID   A0AAV3JGK6
Organism   Streptococcus agalactiae strain GBS68     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 185768..196742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ618_RS01095 (HQ618_01095) - 186458..186823 (+) 366 WP_000285373.1 DUF1033 family protein -
  HQ618_RS01100 (HQ618_01100) comYA 186996..187967 (+) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  HQ618_RS01105 (HQ618_01105) comYB 187861..188904 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  HQ618_RS01110 (HQ618_01110) comGC/cglC 188901..189230 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  HQ618_RS01115 (HQ618_01115) comYD 189205..189618 (+) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  HQ618_RS01120 (HQ618_01120) comGE 189590..189889 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  HQ618_RS01125 (HQ618_01125) comGF 189843..190304 (+) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF -
  HQ618_RS01130 (HQ618_01130) comGG 190282..190653 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  HQ618_RS01135 (HQ618_01135) comYH 190768..191742 (+) 975 WP_001008574.1 class I SAM-dependent methyltransferase Machinery gene
  HQ618_RS01140 (HQ618_01140) - 191774..192967 (+) 1194 WP_000047534.1 acetate kinase -
  HQ618_RS01145 (HQ618_01145) - 193119..193325 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  HQ618_RS01150 (HQ618_01150) - 193384..193521 (+) 138 WP_001865900.1 hypothetical protein -
  HQ618_RS01155 (HQ618_01155) - 193562..194017 (+) 456 WP_000905673.1 hypothetical protein -
  HQ618_RS01160 (HQ618_01160) - 194086..194751 (+) 666 WP_000008113.1 CPBP family intramembrane glutamic endopeptidase -
  HQ618_RS01165 (HQ618_01165) proC 194772..195542 (-) 771 WP_001865901.1 pyrroline-5-carboxylate reductase -
  HQ618_RS01170 (HQ618_01170) pepA 195612..196679 (-) 1068 WP_001281323.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37046.02 Da        Isoelectric Point: 4.5224

>NTDB_id=448679 HQ618_RS01135 WP_001008574.1 190768..191742(+) (comYH) [Streptococcus agalactiae strain GBS68]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK

Nucleotide


Download         Length: 975 bp        

>NTDB_id=448679 HQ618_RS01135 WP_001008574.1 190768..191742(+) (comYH) [Streptococcus agalactiae strain GBS68]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(70-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

67.302

97.222

0.654
  comYH Streptococcus mutans UA140

67.302

97.222

0.654