Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   STAVA1121_RS08065 Genome accession   NZ_CP065488
Coordinates   1522518..1523249 (+) Length   243 a.a.
NCBI ID   WP_002948869.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain AVA1121     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1517518..1528249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS08045 (STAVA1121_07925) - 1518483..1520053 (+) 1571 Protein_1531 IS3-like element ISSth1b family transposase -
  STAVA1121_RS08050 (STAVA1121_07930) - 1520199..1520441 (-) 243 WP_002948868.1 Blp family class II bacteriocin -
  STAVA1121_RS08055 - 1520692..1521093 (-) 402 WP_011226490.1 hypothetical protein -
  STAVA1121_RS08060 (STAVA1121_07935) - 1522061..1522267 (-) 207 WP_347131206.1 bacteriocin class II family protein -
  STAVA1121_RS08065 (STAVA1121_07940) comE/blpR 1522518..1523249 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  STAVA1121_RS08070 comD/blpH 1523786..1524589 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  STAVA1121_RS08075 (STAVA1121_07950) - 1524607..1524768 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  STAVA1121_RS08080 (STAVA1121_07955) comB 1524783..1526150 (-) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27803.11 Da        Isoelectric Point: 6.9136

>NTDB_id=448559 STAVA1121_RS08065 WP_002948869.1 1522518..1523249(+) (comE/blpR) [Streptococcus thermophilus strain AVA1121]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=448559 STAVA1121_RS08065 WP_002948869.1 1522518..1523249(+) (comE/blpR) [Streptococcus thermophilus strain AVA1121]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362