Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   STT19_RS08000 Genome accession   NZ_CP065487
Coordinates   1544530..1545366 (+) Length   278 a.a.
NCBI ID   WP_232991634.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST19     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1539530..1550366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT19_RS07955 (STT19_07980) - 1539555..1539734 (-) 180 WP_011681564.1 hypothetical protein -
  STT19_RS07960 (STT19_07985) - 1539763..1540155 (-) 393 WP_003094909.1 hypothetical protein -
  STT19_RS07965 (STT19_07990) cipB 1540167..1540406 (-) 240 WP_011681565.1 Blp family class II bacteriocin Regulator
  STT19_RS07970 - 1540657..1541058 (-) 402 WP_011226490.1 hypothetical protein -
  STT19_RS07975 (STT19_07995) - 1541913..1542056 (-) 144 WP_014608661.1 hypothetical protein -
  STT19_RS07980 (STT19_08000) - 1542063..1542293 (-) 231 WP_014608662.1 bacteriocin class II family protein -
  STT19_RS07985 (STT19_08005) - 1542650..1542850 (-) 201 WP_011681569.1 hypothetical protein -
  STT19_RS07990 (STT19_08010) - 1542869..1543045 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  STT19_RS07995 (STT19_08015) - 1543295..1544032 (+) 738 WP_011681571.1 response regulator transcription factor -
  STT19_RS08000 comD/blpH 1544530..1545366 (+) 837 WP_232991634.1 ATP-binding protein Regulator
  STT19_RS08005 (STT19_08025) - 1545384..1545545 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  STT19_RS08010 (STT19_08030) comB 1545560..1546927 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  STT19_RS08015 (STT19_08035) comA/nlmT 1546943..1549096 (-) 2154 WP_041827378.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 278 a.a.        Molecular weight: 31935.55 Da        Isoelectric Point: 4.7379

>NTDB_id=448455 STT19_RS08000 WP_232991634.1 1544530..1545366(+) (comD/blpH) [Streptococcus thermophilus strain ST19]
MFGYTLLLQILMYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNS
VRSFRHDYSNLLVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQI
SIPEPIHLIGMETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFERGVSNKGRER
GIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 837 bp        

>NTDB_id=448455 STT19_RS08000 WP_232991634.1 1544530..1545366(+) (comD/blpH) [Streptococcus thermophilus strain ST19]
ATGTTTGGGTACACCCTACTGTTACAGATCCTCATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAA
ACTCTGTGTTGTTATTTCACTTGTCCTCTTCTTCATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAG
GACAATTGGACTTCCAAAAAAATCTCCAGCTAGAAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCT
GTTCGTAGTTTTAGACACGATTATAGTAATCTCTTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGT
CAAAGAAGCCTATGATAGTGTGCTTCAAGAATCCGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTA
ATATTCAGGATAACACTTTGAAAAGCCTTCTGTCCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATT
AGCATCCCAGAACCCATCCACTTGATTGGGATGGAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGC
TATTGAAGGTGCCATTCAAACTCAAAACCCTAAAATTACTATTAGCTTTTGGGAAGATCATTGTTCACAGCTATTATCTA
TTAGCAATACCATAAGTGAAGAAAAAACAGAAACCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGA
GGCATTGGCCTTGCTAATGTCACAGAAATCTTAGATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTC
ATTCACACAACAATTAACAATAACTAAAAAGGCCTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(171-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

37.956

98.561

0.374