Detailed information NTG0448032

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: STCNRZ1151_RS07535
• Genome accession: NZ_CP065483
• Coordinates: 1433648..1435747 (-)
• Length: 699 a.a.
• NCBI ID: WP_059257388.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ1151
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1428648..1440747

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1151_RS07500 (STCNRZ1151_07495)	pptB	1429117..1430151 (-)	1035	WP_373867015.1	ABC transporter permease	Regulator
STCNRZ1151_RS07505 (STCNRZ1151_07500)	pptA	1430151..1430882 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
STCNRZ1151_RS07510 (STCNRZ1151_07505)	-	1430947..1431366 (+)	420	WP_011227486.1	HIT family protein	-
STCNRZ1151_RS07515 (STCNRZ1151_07510)	-	1431363..1431671 (+)	309	WP_011227487.1	hypothetical protein	-
STCNRZ1151_RS07520	-	1432223..1432393 (-)	171	WP_011226439.1	hypothetical protein	-
STCNRZ1151_RS07525 (STCNRZ1151_07520)	-	1432463..1433098 (-)	636	WP_011226440.1	DUF4230 domain-containing protein	-
STCNRZ1151_RS07530	-	1433117..1433242 (-)	126	WP_011681534.1	hypothetical protein	-
STCNRZ1151_RS07535 (STCNRZ1151_07525)	clpE	1433648..1435747 (-)	2100	WP_059257388.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
STCNRZ1151_RS07540 (STCNRZ1151_07530)	-	1436462..1437553 (-)	1092	WP_011227489.1	nucleotidyltransferase	-
STCNRZ1151_RS07545 (STCNRZ1151_07535)	-	1437560..1438300 (-)	741	WP_309252055.1	class I SAM-dependent methyltransferase	-
STCNRZ1151_RS07550 (STCNRZ1151_07540)	rsfS	1438625..1438978 (-)	354	WP_011227491.1	ribosome silencing factor	-
STCNRZ1151_RS07555 (STCNRZ1151_07545)	yqeK	1439002..1439592 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
STCNRZ1151_RS07560 (STCNRZ1151_07550)	-	1439589..1440221 (-)	633	WP_011226445.1	nicotinate-nucleotide adenylyltransferase	-
STCNRZ1151_RS07565 (STCNRZ1151_07555)	yhbY	1440325..1440642 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77182.07 Da
• Isoelectric Point: 4.8262

>NTDB_id=448032 STCNRZ1151_RS07535 WP_059257388.1 1433648..1435747(-) (clpE) [Streptococcus thermophilus strain CNRZ1151]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESIERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=448032 STCNRZ1151_RS07535 WP_059257388.1 1433648..1435747(-) (clpE) [Streptococcus thermophilus strain CNRZ1151]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGCAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCATAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• AAA lid domain (AAA_lid_9) (255-349)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.638	100	0.466
clpC	Lactococcus lactis subsp. cremoris KW2	48.906	91.559	0.448
clpE	Streptococcus pneumoniae D39	48.815	90.558	0.442
clpE	Streptococcus pneumoniae Rx1	48.815	90.558	0.442
clpE	Streptococcus pneumoniae R6	48.815	90.558	0.442
clpE	Streptococcus pneumoniae TIGR4	48.734	90.415	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	45.975	92.418	0.425
clpC	Streptococcus thermophilus LMD-9	43.26	91.273	0.395
clpC	Streptococcus thermophilus LMG 18311	43.103	91.273	0.393
clpC	Streptococcus pneumoniae TIGR4	43.339	89.127	0.386
clpC	Streptococcus pneumoniae Rx1	43.339	89.127	0.386
clpC	Streptococcus pneumoniae D39	43.339	89.127	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.274	88.269	0.382
clpC	Streptococcus mutans UA159	42.995	88.841	0.382