Detailed information NTG0447935

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: STCNRZ760_RS07895
• Genome accession: NZ_CP065482
• Coordinates: 1508017..1510116 (-)
• Length: 699 a.a.
• NCBI ID: WP_180481085.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ760
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1503017..1515116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ760_RS07855 (STCNRZ760_07795)	pptB	1503483..1504520 (-)	1038	WP_180481084.1	ABC transporter permease	Regulator
STCNRZ760_RS07860 (STCNRZ760_07800)	pptA	1504517..1505248 (-)	732	WP_002947523.1	ABC transporter ATP-binding protein	Regulator
STCNRZ760_RS07865 (STCNRZ760_07805)	-	1505313..1505732 (+)	420	WP_002891660.1	HIT family protein	-
STCNRZ760_RS07870 (STCNRZ760_07810)	-	1505729..1506037 (+)	309	WP_180477129.1	hypothetical protein	-
STCNRZ760_RS07875	-	1506079..1506294 (-)	216	WP_096811621.1	hypothetical protein	-
STCNRZ760_RS07880	-	1506589..1506759 (-)	171	WP_011226439.1	hypothetical protein	-
STCNRZ760_RS07885 (STCNRZ760_07820)	-	1506829..1507464 (-)	636	WP_014727665.1	DUF4230 domain-containing protein	-
STCNRZ760_RS07890	-	1507483..1507608 (-)	126	WP_011681534.1	hypothetical protein	-
STCNRZ760_RS07895 (STCNRZ760_07825)	clpE	1508017..1510116 (-)	2100	WP_180481085.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
STCNRZ760_RS07900 (STCNRZ760_07830)	-	1510831..1511922 (-)	1092	WP_180481086.1	nucleotidyltransferase	-
STCNRZ760_RS07905 (STCNRZ760_07835)	-	1511929..1512669 (-)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
STCNRZ760_RS07910 (STCNRZ760_07840)	rsfS	1512994..1513347 (-)	354	WP_011227491.1	ribosome silencing factor	-
STCNRZ760_RS07915 (STCNRZ760_07845)	yqeK	1513371..1513961 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
STCNRZ760_RS07920 (STCNRZ760_07850)	-	1513958..1514590 (-)	633	WP_065972527.1	nicotinate-nucleotide adenylyltransferase	-
STCNRZ760_RS07925 (STCNRZ760_07855)	yhbY	1514694..1515011 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77109.02 Da
• Isoelectric Point: 4.8884

>NTDB_id=447935 STCNRZ760_RS07895 WP_180481085.1 1508017..1510116(-) (clpE) [Streptococcus thermophilus strain CNRZ760]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEGLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKNAK

Nucleotide

• Length: 2100 bp

>NTDB_id=447935 STCNRZ760_RS07895 WP_180481085.1 1508017..1510116(-) (clpE) [Streptococcus thermophilus strain CNRZ760]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTAAATCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGCAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGGCCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACGCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAAATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (255-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.724	100	0.469
clpC	Lactococcus lactis subsp. cremoris KW2	49.062	91.559	0.449
clpE	Streptococcus pneumoniae TIGR4	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	46.13	92.418	0.426
clpC	Streptococcus thermophilus LMD-9	43.26	91.273	0.395
clpC	Streptococcus thermophilus LMG 18311	43.103	91.273	0.393
clpC	Streptococcus pneumoniae TIGR4	43.339	89.127	0.386
clpC	Streptococcus pneumoniae Rx1	43.339	89.127	0.386
clpC	Streptococcus pneumoniae D39	43.339	89.127	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.274	88.269	0.382
clpC	Streptococcus mutans UA159	42.834	88.841	0.381