Detailed information NTG0447858

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: STCNRZ760_RS00315
• Genome accession: NZ_CP065482
• Coordinates: 54206..56764 (+)
• Length: 852 a.a.
• NCBI ID: WP_180481162.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ760
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 49206..61764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ760_RS00295 (STCNRZ760_00295)	purB	49418..50716 (+)	1299	WP_002948159.1	adenylosuccinate lyase	-
STCNRZ760_RS00300 (STCNRZ760_00300)	argS	51580..53271 (-)	1692	WP_180481161.1	arginine--tRNA ligase	-
STCNRZ760_RS00305 (STCNRZ760_00305)	argR	53426..53854 (+)	429	WP_024704313.1	arginine repressor	-
STCNRZ760_RS00310 (STCNRZ760_00310)	-	53854..54213 (+)	360	WP_011225277.1	YlbF family regulator	-
STCNRZ760_RS00315 (STCNRZ760_00315)	hexA	54206..56764 (+)	2559	WP_180481162.1	DNA mismatch repair protein MutS	Machinery gene
STCNRZ760_RS00320 (STCNRZ760_00320)	-	56798..57253 (-)	456	Protein_42	DUF3021 domain-containing protein	-
STCNRZ760_RS00325 (STCNRZ760_00325)	-	57250..57641 (-)	392	Protein_43	LytTR family DNA-binding domain-containing protein	-
STCNRZ760_RS00330 (STCNRZ760_00330)	-	57865..58170 (+)	306	WP_011225281.1	hypothetical protein	-
STCNRZ760_RS00335 (STCNRZ760_00335)	hexB	58222..60165 (+)	1944	WP_173940305.1	DNA mismatch repair endonuclease MutL	Machinery gene
STCNRZ760_RS00340 (STCNRZ760_00340)	-	60295..60516 (+)	222	WP_002949052.1	hypothetical protein	-
STCNRZ760_RS00345 (STCNRZ760_00345)	ruvA	60668..61258 (+)	591	WP_002949053.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95497.71 Da
• Isoelectric Point: 4.7160

>NTDB_id=447858 STCNRZ760_RS00315 WP_180481162.1 54206..56764(+) (hexA) [Streptococcus thermophilus strain CNRZ760]
MAKEKISPGMQQYLDIKKNYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSANNFLVAIDKVGSRFGLSYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLLETDEQVLVNQLNLLLSKETEGYDDVHLIGNSLTDLESSVASKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDKTKTAMGMRLLRTWIDRPLVNQASIIERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDDTLSGLLQELDALPELESLIRSAIDP
DAPATITEGGIIRDGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIAIDRGRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSVDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNSLTYLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPTDLLNRADTILTQLEGETVVIQPQEKVSSQ
EKPAIETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=447858 STCNRZ760_RS00315 WP_180481162.1 54206..56764(+) (hexA) [Streptococcus thermophilus strain CNRZ760]
ATGGCTAAGGAAAAGATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGAAAAATTATCCAGATGCTTTTTTGCTGTT
TCGGATGGGGGATTTTTACGAATTATTTTACGATGATGCTGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACTAGCC
GTAATAAGAATGCAGATAATCCCATTCCTATGGCAGGTGTGCCTTATCATTCAGCTCAAGCATACATTGATGTTTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGATCCTAAGCAGGCTGTCGGTGTGGTAAAGCGTGAGGTTGT
TCAGGTTATCACACCAGGTACAGTGGTTGACAGCTCTAAACCTGATAGTGCCAACAATTTCTTGGTGGCCATTGACAAGG
TTGGAAGTCGTTTTGGTCTTTCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTTAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTGGTTGGATATGATCTACTTGAAACTGACGAACAAGTTTT
AGTGAACCAACTTAACCTACTTCTCTCCAAGGAAACAGAAGGTTACGATGATGTTCACTTGATTGGTAATAGCTTGACAG
ATTTGGAAAGCAGTGTGGCAAGTAAACTTCTCCAGTATGTTCATCGCACTCAGATGCGTGAGCTCAGTCATTTACAAAAA
GCTCAGCACTATGAGATAAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCAAGCTTGGATTTACTGGAAAATGCTAG
AACGGGCAAGAAACACGGTTCTCTTTTCTGGCTCTTGGATAAAACCAAGACAGCCATGGGAATGCGTCTCTTGCGAACTT
GGATTGATCGTCCTTTAGTGAATCAAGCCAGCATCATAGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTT
GAGCGTAGTGACTTGACCGAGAGTCTAAAAGGTGTTTACGATATTGAGCGTCTGGCCAGTCGTGTTTCCTTTGGCAAGGC
TAATCCTAAAGATTTAATTCAGCTAGGTCATACCTTAGCTCAGGTTCCGGTCATTAAGGCAATCTTGGAGTCCTTTAATG
ACGATACCTTGTCAGGTCTTTTACAAGAGTTAGATGCTTTGCCAGAATTAGAGAGTTTGATTCGTTCGGCTATTGATCCT
GATGCTCCAGCAACAATTACAGAAGGTGGTATTATTCGTGATGGTTTTGATGAGACCTTGGACAAGTATCGCAAAGTGAT
GAGCGAGGGGACGTCATGGATTGCGGATATCGAAGCAAAAGAACGCGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGTAAGGCG
ACACTGAAAAATTCGGAGCGTTTTGGAACTGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTAGAAGCACGTGAAAAATC
GTCAACCCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATCGATCGTTTGCAGTCTTTGGCTA
AGGCCATTGCAACAGTCGATGTGCTTCAGAGTTTGGCTGTTACAGCGGAGACAAATCATTATGTTCGTCCTGTTTTTAAT
GATGAGCATCGTATCGCTATTGATCGGGGCCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAA
TACGATTACCTTTGACAGTCAGACCAATATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACCTATATGCGGC
AGTTAGCCTTGTCAGTAGTTATGGCTCAAATGGGGGCTTACGTACCAGCAGATAGTGTTGATTTACCTGTTTTTGACGCC
ATCTATACACGTATAGGCGCCGCAGATGACCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCA
GGCCATTAAGCGAGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGGCGTGGGACAGCCACTTATGATGGTATGG
CTTTGGCCCAGTCTATTATTGAGTTTATTCATGACAAGGTTGGGGCTAAGACCATGTTTGCTACCCATTATCATGAGTTG
ACTGCGCTGTCAAACAGTTTGACATACCTTGTCAACGTCCATGTTGCGACACTTGAAAAGGATGGCGAAGTGACTTTCCT
CCACAAAATTGTCGATGGTCCAGCCGATAAATCGTATGGTATTCATGTAGCTAAAATTGCAGGTTTACCAACAGATTTAT
TGAACCGTGCTGACACCATATTGACACAATTAGAAGGAGAGACAGTTGTAATCCAACCTCAGGAAAAGGTATCGTCTCAA
GAAAAGCCTGCCATTGAAACGCATGTCAACGAGCAAATCTCTCTCTTTGATGACTTTACTGAAAATCCGGTTCTTCAAGA
GTTGCGTGATTTGGACATTTACAACATGACACCGATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.944	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	35.788	100	0.365