Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ST4134_RS08830 Genome accession   NZ_CP065478
Coordinates   1700484..1700777 (-) Length   97 a.a.
NCBI ID   WP_024704238.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4134     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1695484..1705777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4134_RS08790 (ST4134_08765) - 1695885..1696328 (-) 444 WP_011681680.1 hypothetical protein -
  ST4134_RS08795 - 1696402..1696740 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  ST4134_RS08800 - 1696784..1697059 (-) 276 WP_011681681.1 hypothetical protein -
  ST4134_RS08805 (ST4134_08775) - 1697071..1697269 (-) 199 Protein_1677 helix-turn-helix transcriptional regulator -
  ST4134_RS08810 (ST4134_08780) - 1697518..1698711 (-) 1194 WP_014608740.1 acetate kinase -
  ST4134_RS08815 (ST4134_08785) comGH 1698767..1699723 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  ST4134_RS08820 (ST4134_08790) comGG 1699768..1700085 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  ST4134_RS08825 (ST4134_08795) comGF 1700063..1700500 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  ST4134_RS08830 (ST4134_08800) comGE 1700484..1700777 (-) 294 WP_024704238.1 competence type IV pilus minor pilin ComGE Machinery gene
  ST4134_RS08835 (ST4134_08805) comGD 1700749..1701177 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  ST4134_RS08840 (ST4134_08810) comGC 1701137..1701463 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ST4134_RS08845 (ST4134_08815) comGB 1701460..1702560 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  ST4134_RS08850 (ST4134_08820) comGA/cglA/cilD 1702442..1703383 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  ST4134_RS08855 (ST4134_08825) - 1703464..1703826 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.78 Da        Isoelectric Point: 10.6199

>NTDB_id=447527 ST4134_RS08830 WP_024704238.1 1700484..1700777(-) (comGE) [Streptococcus thermophilus strain 4134]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQK
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=447527 ST4134_RS08830 WP_024704238.1 1700484..1700777(-) (comGE) [Streptococcus thermophilus strain 4134]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGAAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361