Detailed information NTG0447496

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ST4134_RS06830
• Genome accession: NZ_CP065478
• Coordinates: 1315241..1316326 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain 4134
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1310241..1321326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4134_RS06800 (ST4134_06785)	-	1310605..1311420 (-)	816	WP_011226298.1	Cof-type HAD-IIB family hydrolase	-
ST4134_RS06805 (ST4134_06790)	-	1311413..1312207 (-)	795	WP_011681412.1	HAD-IIB family hydrolase	-
ST4134_RS06810 (ST4134_06795)	-	1312392..1312769 (+)	378	WP_011681413.1	GntR family transcriptional regulator	-
ST4134_RS06815 (ST4134_06800)	-	1312774..1313472 (+)	699	WP_023909821.1	ABC transporter ATP-binding protein	-
ST4134_RS06820 (ST4134_06805)	-	1313484..1314269 (+)	786	WP_002951425.1	hypothetical protein	-
ST4134_RS06825 (ST4134_06810)	-	1314319..1315248 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
ST4134_RS06830 (ST4134_06815)	amiE	1315241..1316326 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
ST4134_RS06835 (ST4134_06820)	amiD	1316336..1317262 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
ST4134_RS06840 (ST4134_06825)	amiC	1317262..1318755 (-)	1494	WP_011681416.1	ABC transporter permease	Regulator
ST4134_RS06845 (ST4134_06830)	amiA	1318817..1320784 (-)	1968	WP_024703940.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=447496 ST4134_RS06830 WP_011226304.1 1315241..1316326(-) (amiE) [Streptococcus thermophilus strain 4134]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=447496 ST4134_RS06830 WP_011226304.1 1315241..1316326(-) (amiE) [Streptococcus thermophilus strain 4134]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526