Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   ST4052_RS07635 Genome accession   NZ_CP065476
Coordinates   1467675..1468478 (+) Length   267 a.a.
NCBI ID   WP_224103634.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4052     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1462675..1473478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4052_RS07620 (ST4052_07690) - 1464358..1465757 (+) 1400 Protein_1447 IS3-like element ISSth1b family transposase -
  ST4052_RS07625 (ST4052_07695) - 1465903..1466157 (-) 255 WP_002951792.1 Blp family class II bacteriocin -
  ST4052_RS07630 (ST4052_07700) comE/blpR 1466407..1467138 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  ST4052_RS07635 comD/blpH 1467675..1468478 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  ST4052_RS07640 (ST4052_07710) - 1468496..1468657 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST4052_RS07645 (ST4052_07715) - 1468672..1470040 (-) 1369 Protein_1452 bacteriocin secretion accessory protein -
  ST4052_RS07650 (ST4052_07720) - 1470056..1472208 (-) 2153 Protein_1453 peptide cleavage/export ABC transporter -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30835.17 Da        Isoelectric Point: 4.8309

>NTDB_id=447306 ST4052_RS07635 WP_224103634.1 1467675..1468478(+) (comD/blpH) [Streptococcus thermophilus strain 4052]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=447306 ST4052_RS07635 WP_224103634.1 1467675..1468478(+) (comD/blpH) [Streptococcus thermophilus strain 4052]
ATGTATCTTGAAAACACTACTCACTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGAAAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAGAAAAATCTCCAGCTAG
AGAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGTCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAATACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGATTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCATAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363