Detailed information    

insolico Bioinformatically predicted

Overview


Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   GE021_RS02125 Genome accession   NZ_CP053792
Coordinates   419782..420264 (+) Length   160 a.a.
NCBI ID   WP_125075072.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_1     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 420866..421036 419782..420264 flank 602


Gene organization within MGE regions


Location: 419782..421036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS02125 (GE021_002125) comX/sigX/comX2/sigX2 419782..420264 (+) 483 WP_125075072.1 competence protein ComX Regulator

Sequence


Protein


Download         Length: 160 a.a.        Molecular weight: 19362.20 Da        Isoelectric Point: 6.5020

>NTDB_id=447262 GE021_RS02125 WP_125075072.1 419782..420264(+) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_77_1]
MSIETGVVFEKVKPIILKLKRHYYIQLWEREDWLQEGYLILVSLLEQHPELLWEDERLYRYFKTKFSSYLKDVLRQQESQ
KRQFHKMAYEEIGDVAHAIPSGGLWLDDYVAYREVVEALEGQLSEEERLQFQALVRGERFKGRQALLRKLRPYFEGFERS

Nucleotide


Download         Length: 483 bp        

>NTDB_id=447262 GE021_RS02125 WP_125075072.1 419782..420264(+) (comX/sigX/comX2/sigX2) [Streptococcus canis strain HL_77_1]
ATGTCGATAGAGACAGGAGTAGTGTTTGAGAAGGTGAAACCCATTATCTTGAAGTTGAAGCGTCATTATTATATTCAATT
GTGGGAGAGGGAGGATTGGTTACAGGAAGGGTATTTGATATTGGTGAGTCTCCTAGAGCAGCATCCTGAATTACTTTGGG
AAGACGAACGGTTGTATCGTTATTTTAAGACTAAGTTTTCATCGTATTTGAAGGATGTCTTGCGTCAGCAAGAAAGTCAG
AAGCGTCAGTTTCATAAAATGGCTTATGAGGAGATAGGTGATGTAGCACATGCGATTCCATCAGGTGGGTTATGGTTGGA
TGATTACGTGGCCTATAGGGAGGTGGTTGAGGCGTTAGAAGGGCAGTTGAGTGAAGAGGAGCGGTTACAGTTTCAGGCCT
TGGTGAGAGGGGAACGGTTTAAGGGAAGGCAGGCCTTGCTTAGGAAGTTGCGTCCTTATTTTGAGGGATTTGAGAGAAGT
TAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

78.981

98.125

0.775

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

78.981

98.125

0.775

  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

78.344

98.125

0.769

  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

78.344

98.125

0.769

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

77.707

98.125

0.762

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

77.707

98.125

0.762

  comX/sigX Streptococcus mutans UA159

53.947

95

0.512

  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

93.75

0.456

  comX Streptococcus thermophilus LMG 18311

44.371

94.375

0.419

  comX Streptococcus thermophilus LMD-9

44.371

94.375

0.419

  comX Streptococcus sobrinus strain NIDR 6715-7

43.709

94.375

0.413

  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

43.046

94.375

0.406

  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

43.046

94.375

0.406

  comX Streptococcus salivarius SK126

42.384

94.375

0.4

  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

42.384

94.375

0.4

  comX/sigX Streptococcus salivarius strain HSISS4

42.384

94.375

0.4

  comX/comX2 Streptococcus pneumoniae Rx1

42

93.75

0.394

  comX/comX1 Streptococcus pneumoniae Rx1

42

93.75

0.394

  comX/comX2 Streptococcus pneumoniae D39

42

93.75

0.394

  comX/comX1 Streptococcus pneumoniae D39

42

93.75

0.394

  comX/comX2 Streptococcus pneumoniae R6

42

93.75

0.394

  comX/comX1 Streptococcus pneumoniae R6

42

93.75

0.394

  comX/comX2 Streptococcus pneumoniae TIGR4

42

93.75

0.394

  comX/comX1 Streptococcus pneumoniae TIGR4

42

93.75

0.394

  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

41.06

94.375

0.388

  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

41.06

94.375

0.388

  comX/sigX Streptococcus suis D9

40

93.75

0.375

  comX/sigX Streptococcus suis isolate S10

40

93.75

0.375

  comX/sigX Streptococcus suis P1/7

40

93.75

0.375

  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

39.073

94.375

0.369