Detailed information NTG0447238

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GE022_RS09710
• Genome accession: NZ_CP053790
• Coordinates: 2002602..2005046 (-)
• Length: 814 a.a.
• NCBI ID: WP_164405466.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_77_2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1997602..2010046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE022_RS09685 (GE022_009675)	-	1997620..1998090 (+)	471	WP_159306056.1	8-oxo-dGTP diphosphatase	-
GE022_RS09690 (GE022_009680)	-	1998433..1999650 (-)	1218	WP_164405464.1	MFS transporter	-
GE022_RS09695 (GE022_009685)	-	1999656..2000156 (-)	501	WP_164405465.1	lanthionine synthetase LanC family protein	-
GE022_RS10775	-	2000122..2000217 (-)	96	Protein_1870	Rgg/GadR/MutR family transcriptional regulator	-
GE022_RS09700 (GE022_009690)	groL	2000473..2002098 (-)	1626	WP_003045626.1	chaperonin GroEL	-
GE022_RS09705 (GE022_009695)	groES	2002134..2002424 (-)	291	WP_003045628.1	co-chaperone GroES	-
GE022_RS09710 (GE022_009700)	clpC	2002602..2005046 (-)	2445	WP_164405466.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GE022_RS09715 (GE022_009705)	-	2005046..2005507 (-)	462	WP_093999117.1	CtsR family transcriptional regulator	-
GE022_RS09720 (GE022_009710)	-	2005706..2005909 (-)	204	WP_003045634.1	cold-shock protein	-
GE022_RS09725 (GE022_009715)	-	2006248..2007204 (+)	957	WP_093999116.1	amidohydrolase family protein	-
GE022_RS09730 (GE022_009720)	-	2007340..2007768 (+)	429	WP_003045638.1	MarR family winged helix-turn-helix transcriptional regulator	-
GE022_RS09735 (GE022_009725)	-	2007782..2009173 (+)	1392	WP_164405467.1	GNAT family N-acetyltransferase	-
GE022_RS09740 (GE022_009730)	-	2009271..2009549 (+)	279	WP_003045642.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90347.00 Da
• Isoelectric Point: 6.7392

>NTDB_id=447238 GE022_RS09710 WP_164405466.1 2002602..2005046(-) (clpC) [Streptococcus canis strain HL_77_2]
MIMYSLKMQEIFRQAQFQAARFDSHYLETWHILLAMARVDQSLAGLVLSEFDAKVAVEEYEAAAILAIGKSPKDQVSHVD
FKPQSKTLTNVLQFAQAISQITKDPEVGSEHVLFAMLLNPDIMASRLLEMAGYRIKDKGNGEPRLADLRKAIEIHAGYSK
ETIKTIHELRKPKKTKVQGTFSDMMKPPSTTGDLADFTRDLTEMAKQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVNGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNLEDAYQILLGLKTSYETYHNVSISD
QAVHTAVKMAHRYLTSKNLPDSAIDLLDEASATVQSMVKKSSSEIITPIDQALLDGDIKKVSRLLAKEAKGQTRRPRPVT
EDDIMATLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQENMREVVKIMVQPLIASLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGDLASGHTL
KIGLSHGKLSFNVG

Nucleotide

• Length: 2445 bp

>NTDB_id=447238 GE022_RS09710 WP_164405466.1 2002602..2005046(-) (clpC) [Streptococcus canis strain HL_77_2]
ATGATCATGTATTCATTGAAGATGCAAGAAATCTTTAGGCAGGCACAGTTTCAAGCAGCCCGCTTTGACAGCCACTACCT
AGAAACTTGGCATATCTTGTTAGCCATGGCTAGAGTTGACCAGTCCTTAGCAGGTCTAGTGCTAAGTGAATTTGATGCTA
AAGTTGCAGTGGAAGAATACGAAGCTGCCGCTATTTTAGCTATAGGAAAAAGTCCTAAAGATCAGGTGTCACACGTGGAT
TTCAAGCCTCAATCCAAGACCTTGACGAATGTGTTACAGTTTGCGCAGGCTATTAGTCAAATCACTAAAGACCCAGAAGT
CGGCTCTGAGCATGTGCTCTTTGCCATGCTACTCAATCCTGATATTATGGCAAGTCGTCTCTTGGAAATGGCTGGGTATC
GCATCAAAGATAAAGGAAATGGGGAACCTCGCTTAGCTGATTTGCGAAAGGCCATTGAGATTCACGCAGGTTATAGCAAA
GAAACCATTAAGACTATCCATGAGTTACGCAAACCAAAGAAAACGAAGGTTCAAGGAACCTTCTCAGATATGATGAAGCC
ACCAAGCACGACGGGTGATTTGGCTGACTTCACCAGAGATTTGACCGAGATGGCAAAACAAGGTCTGCTAGAGCCTGTCA
TTGGTCGTGATGCCGAAGTATCTCGCATGATTCAAGTGCTCAGTCGTAAAACCAAAAACAATCCTGTTCTTGTTGGAGAT
GCAGGGGTTGGTAAAACTGCCCTTGCCTATGGTCTTGCCCAACGTATTGTGAATGGAGCCATTCCTTATGAACTGCAAGA
CATGCGCGTCCTCGAATTGGACATGATGAGCGTCGTTGCGGGGACACGTTTTCGTGGTGATTTTGAAGAACGCATGAACC
AGATTATTGATGACATTGAAGCAGATGGCAAGATTATCCTCTTTGTGGATGAATTGCATACCATTATGGGGTCAGGAAGC
GGTATTGATAGCACACTTGATGCTGCTAATATTTTGAAACCAGCCCTATCTCGTGGCACCCTTCACATGGTCGGAGCAAC
AACGCAGGAAGAGTACCAAAAACATATTGAAAAGGACGCCGCTCTTTCTCGCCGCTTTGCCAAAATTTTAATTGAAGAGC
CTAACCTAGAAGACGCCTATCAGATTTTACTAGGTTTGAAGACTTCCTATGAAACCTACCATAATGTGTCAATTTCTGAT
CAGGCAGTGCATACAGCTGTTAAAATGGCGCATCGCTACCTAACTAGTAAAAATCTTCCAGATTCAGCCATCGATTTGTT
GGACGAAGCTAGCGCTACAGTCCAAAGCATGGTTAAAAAATCAAGTTCGGAAATCATCACACCAATAGATCAGGCACTTC
TTGACGGTGATATAAAAAAGGTTTCACGTCTTTTGGCCAAAGAAGCTAAGGGGCAGACGAGAAGGCCAAGGCCAGTAACA
GAAGACGATATTATGGCAACCCTGAGCAAATTATCAGGGATTCCATTGGAAAAACTCAGTCAGGCTGATAGCAAAAAATA
CCTCAATCTTGAAAAAGAGTTGCACAAGCGCGTGATTGGACAAGAAGACGCTGTTTCAGCCATTTCTAGAGCAATCCGTC
GTAATCAATCAGGTATTCGCACTGGTAAACGTCCAATTGGTTCTTTCATGTTCCTTGGACCTACTGGTGTTGGGAAGACT
GAATTAGCTAAAGCTTTGGCAGAAGTCCTCTTTGATGACGCGTCAGCCCTTATCCGCTTTGACATGTCAGAGTATATGGA
AAAATTTGCGGCATCTCGCCTTAATGGAGCGCCTCCAGGCTATGTTGGTTACGATGAGGGCGGTGAATTAACAGAGAAGG
TCAGAAATAAGCCTTATTCTGTCCTCCTCTTTGACGAGGTGGAAAAAGCCCACCCTGACATTTTCAACGTGCTCTTACAA
GTGCTTGATGACGGTATGTTGACAGATAGCCGTGGGCGTAAGGTGGACTTTTCAAACACCATTATTATCATGACTAGTAA
TCTAGGGGCAACAGCTCTGCGGGATGATAAAACAGTTGGCTTTGGGGTAAAAGGTATCAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAATTGAAAAAAGCTTATCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAT
AGCCTTACCCAAGAGAATATGAGGGAAGTGGTTAAGATTATGGTGCAGCCATTGATTGCTAGTTTAGCAGAAAAAGGCAT
TACCCTAAAATTCCAGCCAATGGCTCTCAAGTACCTTTCAGAGGAAGGCTATGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGTACTTTGCAAACGCAGGTAGAAGACAAACTATCCGAATTGATTCTTGCTGGTGACTTGGCAAGTGGTCACACCCTG
AAAATTGGGCTTTCCCATGGCAAACTCAGCTTTAACGTTGGGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-132)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.015	99.877	0.759
clpC	Streptococcus thermophilus LMD-9	72.426	100	0.726
clpC	Streptococcus thermophilus LMG 18311	72.426	100	0.726
clpC	Streptococcus pneumoniae TIGR4	65.725	100	0.657
clpC	Streptococcus pneumoniae Rx1	65.725	100	0.657
clpC	Streptococcus pneumoniae D39	65.725	100	0.657
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.568	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	43.63	100	0.446