Detailed information NTG0447184

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GE023_RS09995
• Genome accession: NZ_CP053789
• Coordinates: 2028788..2031232 (-)
• Length: 814 a.a.
• NCBI ID: WP_164401526.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_98_2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2023788..2036232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE023_RS09970 (GE023_009965)	-	2023791..2024261 (+)	471	WP_159306056.1	8-oxo-dGTP diphosphatase	-
GE023_RS09975 (GE023_009970)	-	2024604..2025821 (-)	1218	WP_003045622.1	MFS transporter	-
GE023_RS09980 (GE023_009975)	-	2025827..2026342 (-)	516	WP_138114335.1	lanthionine synthetase LanC family protein	-
GE023_RS10775	-	2026323..2026403 (-)	81	Protein_1929	XRE family transcriptional regulator	-
GE023_RS09985 (GE023_009980)	groL	2026659..2028284 (-)	1626	WP_003045626.1	chaperonin GroEL	-
GE023_RS09990 (GE023_009985)	groES	2028320..2028610 (-)	291	WP_003045628.1	co-chaperone GroES	-
GE023_RS09995 (GE023_009990)	clpC	2028788..2031232 (-)	2445	WP_164401526.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GE023_RS10000 (GE023_009995)	-	2031232..2031693 (-)	462	WP_093999117.1	CtsR family transcriptional regulator	-
GE023_RS10005 (GE023_010000)	-	2031892..2032095 (-)	204	WP_003045634.1	cold-shock protein	-
GE023_RS10010 (GE023_010005)	-	2032433..2033389 (+)	957	WP_093999116.1	amidohydrolase family protein	-
GE023_RS10015 (GE023_010010)	-	2033525..2033953 (+)	429	WP_003045638.1	MarR family winged helix-turn-helix transcriptional regulator	-
GE023_RS10020 (GE023_010015)	-	2033967..2035358 (+)	1392	WP_159306054.1	GNAT family N-acetyltransferase	-
GE023_RS10025 (GE023_010020)	-	2035456..2035734 (+)	279	WP_003045642.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90360.09 Da
• Isoelectric Point: 6.8332

>NTDB_id=447184 GE023_RS09995 WP_164401526.1 2028788..2031232(-) (clpC) [Streptococcus canis strain HL_98_2]
MIMYSLKMQEIFRQAQFQAARFDSHYLETWHILLAMARVDQSLAGLVLSEFDAKVAVEEYEAAAILAIGKNLKGQVSHVD
FKPQSKTLTNVLQFAQAISQITKDPEVGSEHVLFAMLLNPDIMASRLLEMAGYRIKDKGNGEPRLADLRKAIEIHAGYSK
ETIKTIHELRKPKKTKVQGTFSDMMKPPSTTGDLADFTRDLTEMAKQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVNGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNLEDAYQILLGLKTSYETYHNVSISD
QAVHTAVKMAHRYLTSKNLPDSAIDLLDEASATVQSMVKKSSSEIITPIDQALLDGDIKKVSRLLAKEAKGQTRRPRPVT
EDDIMATLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDVSALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQENMREVVKIMVQPLIASLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGDLASGHTL
KIGLSHGKLSFNVG

Nucleotide

• Length: 2445 bp

>NTDB_id=447184 GE023_RS09995 WP_164401526.1 2028788..2031232(-) (clpC) [Streptococcus canis strain HL_98_2]
ATGATCATGTATTCATTGAAGATGCAAGAAATCTTTAGGCAGGCACAGTTTCAAGCAGCCCGCTTTGACAGCCACTACCT
AGAAACTTGGCATATCTTGTTAGCCATGGCTAGAGTTGACCAGTCCTTAGCAGGTCTAGTGCTAAGTGAATTTGATGCTA
AAGTTGCAGTGGAAGAATACGAAGCTGCCGCTATTTTAGCTATAGGAAAAAATCTTAAAGGTCAGGTGTCACACGTGGAT
TTCAAGCCTCAATCCAAGACCTTGACGAATGTGTTACAGTTTGCGCAGGCTATTAGTCAAATCACTAAAGACCCAGAAGT
CGGCTCTGAACATGTGCTCTTTGCCATGCTACTCAATCCTGATATTATGGCGAGTCGTCTCTTGGAAATGGCTGGGTATC
GCATCAAAGATAAAGGAAATGGGGAACCTCGCTTAGCTGATTTGCGAAAGGCCATTGAGATTCACGCAGGTTATAGCAAA
GAAACCATTAAGACTATCCATGAGTTACGCAAACCAAAGAAAACGAAGGTTCAAGGAACCTTCTCAGATATGATGAAACC
ACCAAGCACGACGGGTGATTTGGCTGACTTCACCAGAGATTTGACCGAGATGGCAAAACAGGGTCTGCTAGAGCCTGTCA
TTGGTCGTGATGCCGAAGTATCTCGCATGATTCAAGTGCTCAGTCGTAAAACCAAAAATAATCCTGTTCTTGTTGGAGAT
GCAGGGGTTGGTAAAACTGCCCTTGCCTATGGTCTTGCCCAACGTATTGTGAATGGAGCCATTCCTTATGAACTGCAAGA
CATGCGCGTCCTCGAATTGGACATGATGAGCGTCGTTGCGGGGACACGTTTTCGTGGTGATTTTGAAGAACGCATGAACC
AGATTATTGATGACATTGAAGCAGATGGCAAGATTATCCTCTTTGTGGATGAATTGCATACCATTATGGGGTCAGGAAGC
GGTATTGATAGCACACTTGATGCTGCTAATATTTTGAAACCAGCCCTATCTCGTGGCACCCTTCACATGGTCGGAGCAAC
AACGCAGGAAGAGTACCAAAAACATATTGAAAAGGACGCCGCTCTTTCTCGCCGCTTTGCCAAAATTTTAATTGAAGAGC
CTAACCTAGAAGACGCCTATCAGATTTTACTAGGTTTGAAGACTTCCTATGAAACCTACCATAATGTGTCAATTTCTGAT
CAGGCAGTGCATACAGCTGTTAAAATGGCGCATCGCTACCTAACTAGTAAAAATCTTCCAGATTCAGCCATCGATTTGTT
GGACGAAGCTAGCGCTACAGTCCAAAGCATGGTTAAAAAATCAAGTTCGGAAATCATCACACCAATAGATCAGGCACTTC
TTGACGGTGATATAAAAAAGGTTTCACGTCTTTTGGCCAAAGAAGCTAAGGGGCAGACGAGAAGGCCAAGGCCAGTAACA
GAAGACGATATTATGGCAACCCTGAGCAAATTATCAGGGATTCCATTGGAAAAACTCAGTCAGGCTGATAGCAAAAAATA
CCTCAATCTTGAAAAAGAATTGCACAAGCGCGTGATTGGACAAGAAGACGCTGTTTCAGCCATTTCTAGAGCAATCCGTC
GTAATCAATCGGGTATTCGCACTGGTAAACGTCCAATTGGTTCTTTCATGTTCCTTGGACCTACTGGTGTTGGGAAGACT
GAATTGGCTAAAGCTTTGGCAGAAGTCCTCTTTGATGACGTGTCAGCCCTTATCCGCTTTGACATGTCAGAGTATATGGA
AAAATTTGCGGCATCTCGCCTTAATGGAGCGCCTCCAGGCTATGTCGGTTACGATGAGGGCGGTGAATTAACAGAGAAGG
TCAGAAATAAGCCTTATTCTGTCCTCCTCTTTGACGAGGTGGAAAAAGCCCACCCTGACATTTTCAACGTGCTCTTACAA
GTGCTTGATGACGGTATGTTGACAGATAGCCGTGGGCGTAAGGTGGACTTCTCAAACACCATTATTATCATGACTAGTAA
TCTAGGGGCAACAGCTCTGCGGGATGATAAAACAGTTGGCTTTGGGGTAAAAGGTATCAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAAAAAGCTTATCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAT
AGCCTTACCCAAGAGAATATGAGGGAAGTGGTCAAGATTATGGTGCAGCCATTGATTGCTAGTTTAGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCTCTCAAGTACCTTTCAGAGGAAGGCTATGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGTACTTTGCAAACGCAGGTAGAAGACAAACTATCCGAATTGATTCTTGCTGGTGACTTGGCAAGTGGTCACACCCTG
AAAATTGGGCTTTCCCATGGCAAACTTAGCTTTAACGTTGGGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-132)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	75.892	99.877	0.758
clpC	Streptococcus thermophilus LMG 18311	72.181	100	0.724
clpC	Streptococcus thermophilus LMD-9	72.181	100	0.724
clpC	Streptococcus pneumoniae TIGR4	65.602	100	0.656
clpC	Streptococcus pneumoniae Rx1	65.602	100	0.656
clpC	Streptococcus pneumoniae D39	65.602	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.568	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	43.87	100	0.448