Detailed information NTG0044688

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: C270_RS07255
• Genome accession: NC_018673
• Coordinates: 1476041..1478167 (-)
• Length: 708 a.a.
• NCBI ID: WP_014974922.1
• Uniprot ID: K0DF82
• Organism: Leuconostoc carnosum JB16
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1471041..1483167

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C270_RS08785 (C270_07000)	-	1471810..1473747 (-)	1938	WP_014974919.1	C39 family peptidase	-
C270_RS07245 (C270_07005)	-	1473906..1474841 (-)	936	WP_014974920.1	DUF1810 family protein	-
C270_RS07250 (C270_07010)	-	1474956..1475945 (-)	990	WP_041773169.1	nucleoid-associated protein	-
C270_RS07255 (C270_07015)	clpE	1476041..1478167 (-)	2127	WP_014974922.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
C270_RS07260 (C270_07020)	-	1478223..1478447 (-)	225	WP_014974923.1	hypothetical protein	-
C270_RS07265 (C270_07025)	rlmD	1478751..1480241 (+)	1491	WP_014974924.1	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	-
C270_RS07270 (C270_07030)	-	1480282..1481130 (-)	849	WP_014974925.1	membrane protein	-
C270_RS07275 (C270_07035)	-	1481108..1481464 (-)	357	WP_014974926.1	PadR family transcriptional regulator	-
C270_RS07290 (C270_07040)	-	1481973..1483079 (-)	1107	WP_014974927.1	AI-2E family transporter	-

Sequence

Protein

• Length: 708 a.a.
• Molecular weight: 77600.79 Da
• Isoelectric Point: 4.7816

>NTDB_id=44688 C270_RS07255 WP_014974922.1 1476041..1478167(-) (clpE) [Leuconostoc carnosum JB16]
MANNNDLFNDPFGSDMNNIFNNMMGNMNGMNSEKRRYLINGREVTPEEFVKYRQTGQLPQGQGNPAVGNGQQQEAVQQPG
QTKQEGMLAKLGRNLTKEARDGLLDPVIGRNKEIQETAEILGRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPASIK
DKEIYSIDISSLEAGTQFRGAFEENIQNLMKEVKAAGNVILFFDEIHQILGAGSTGGEDGGKGLADIIKPALSRGEISLI
GATTQDEYRNTIMKNAALARRFNEVTVNAPSPKDTLEILKGISKLYEKHHHVELPEDVLKAAVDYAVQYIPQRSLPDKAI
DLLDMTAAHLSAKNPVTDKVSLEKQMTDVKVKQEKAVADEDYEAALKYKNQIADFEKQISGADEATKVIATSNDVAESVE
RLTGIPVAQMGASDIERLKTIGQRLAGKVIGQDEAVNMVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALD
MFGSKENIVRLDMSEYSDLTAVSKLIGTTAGYIGYDDNSNTLTEKVRRNPYSIVLLDEIEKANPQVLTLLLQVMDDGRLT
DGQGNVVNFKNTVIIATSNAGFSDKSEGELMDRLAPYFRPEFLNRFNGVIEFSALSKQDLKQIIDLMLNDVNKTLAKKEL
TLKVSDDVKDHLIEAGYDEALGARPLRRVIEQQIRDQVTDFYLDNPGEKDLQADLVDDKVVISAVVSQ

Nucleotide

• Length: 2127 bp

>NTDB_id=44688 C270_RS07255 WP_014974922.1 1476041..1478167(-) (clpE) [Leuconostoc carnosum JB16]
ATGGCTAACAATAATGATTTGTTCAATGATCCATTTGGATCAGATATGAATAATATTTTTAATAATATGATGGGAAATAT
GAATGGTATGAATTCGGAGAAACGTCGTTACTTAATTAACGGTCGTGAAGTAACCCCGGAAGAATTCGTGAAGTACCGTC
AAACAGGACAGTTACCACAAGGACAAGGTAATCCAGCTGTTGGTAATGGGCAGCAACAAGAAGCAGTACAGCAACCTGGA
CAAACTAAGCAAGAGGGGATGCTGGCAAAGCTAGGTCGTAATTTGACCAAAGAAGCACGTGACGGGTTACTTGATCCAGT
CATTGGCCGTAATAAAGAAATTCAAGAAACTGCTGAAATATTAGGACGTCGTACTAAAAATAACCCAGTACTTGTGGGTG
ATGCCGGGGTTGGTAAGACAGCAGTTGTTGAAGGTTTAGCACAAGCAATTGTTAATGGTGATGTGCCCGCATCAATTAAA
GACAAGGAAATTTATAGTATTGATATTTCTAGTTTGGAAGCAGGCACACAATTCCGTGGCGCTTTTGAAGAAAATATTCA
AAATTTGATGAAAGAGGTTAAAGCTGCAGGAAATGTTATCCTGTTCTTCGATGAAATTCATCAAATATTAGGTGCTGGAT
CAACCGGTGGTGAAGATGGTGGCAAAGGTTTAGCTGATATTATTAAGCCAGCATTGAGCCGTGGTGAGATTTCATTAATT
GGTGCCACAACGCAAGATGAGTATCGTAACACTATCATGAAGAATGCAGCTTTGGCACGTCGTTTCAATGAAGTAACAGT
TAATGCACCTTCACCAAAAGATACACTGGAAATTTTGAAGGGTATTTCAAAACTATATGAGAAGCATCATCATGTAGAAT
TACCGGAAGATGTTTTAAAGGCAGCCGTTGATTATGCCGTGCAATATATTCCACAACGCTCATTGCCTGATAAGGCAATC
GATTTACTTGATATGACGGCTGCACATTTGTCAGCTAAGAATCCAGTGACGGATAAAGTTAGTTTGGAAAAGCAAATGAC
TGATGTGAAAGTAAAGCAAGAAAAAGCCGTTGCTGACGAAGATTATGAAGCAGCGTTGAAGTATAAGAACCAAATTGCAG
ATTTTGAGAAGCAAATATCGGGAGCAGATGAGGCCACTAAGGTTATTGCCACGTCTAACGATGTTGCGGAATCTGTCGAA
CGATTAACTGGTATTCCTGTTGCTCAAATGGGCGCTTCGGATATTGAACGTTTGAAGACAATAGGTCAACGATTAGCAGG
TAAAGTTATTGGACAAGATGAAGCCGTCAATATGGTAGCACGTGCTATACGTCGTAATCGTGCTGGTTTTGATGAAGGTA
ATCGGCCAATTGGTAGTTTCCTATTTGTTGGGCCAACCGGCGTTGGTAAGACGGAGTTAGCTAAACAATTAGCACTTGAT
ATGTTTGGTAGTAAAGAAAATATTGTACGTTTAGATATGTCAGAGTATTCGGATCTCACAGCCGTATCTAAGTTAATTGG
TACAACAGCTGGATATATTGGATATGATGATAACAGTAATACTTTAACAGAGAAAGTTCGTCGTAATCCCTATTCAATTG
TCCTGCTAGATGAAATTGAAAAGGCAAATCCACAAGTATTGACTTTGTTACTACAAGTTATGGATGATGGTCGCTTAACT
GATGGGCAAGGTAATGTGGTTAACTTTAAGAATACCGTGATTATTGCCACATCAAATGCCGGCTTTTCAGATAAGAGTGA
AGGTGAGCTAATGGATCGATTGGCACCATACTTCCGTCCAGAATTCTTGAATCGTTTTAATGGTGTGATTGAATTTTCAG
CATTAAGTAAGCAAGACTTGAAGCAGATTATTGATTTGATGTTAAATGATGTGAATAAGACATTGGCTAAGAAAGAGTTA
ACATTAAAGGTATCTGACGATGTTAAAGATCATTTGATTGAAGCGGGTTACGATGAGGCATTAGGTGCACGACCACTACG
TCGTGTGATTGAGCAACAAATTCGTGATCAAGTAACCGACTTTTATCTAGATAATCCTGGTGAAAAAGACTTACAAGCTG
ATTTAGTTGATGACAAAGTTGTCATTTCAGCAGTCGTTAGTCAGTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (615-686)

• AAA domain (Cdc48 subfamily) (AAA_2) (455-607)

• AAA lid domain (AAA_lid_9) (271-369)

• ATPase family associated with various cellular activities (AAA) (AAA) (130-262)

3D structure

• AlphaFold DB: K0DF82

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	50.077	91.384	0.458
clpC	Lactococcus lactis subsp. cremoris KW2	48.858	92.797	0.453
clpE	Streptococcus pneumoniae D39	49.134	89.689	0.441
clpE	Streptococcus pneumoniae R6	49.134	89.689	0.441
clpE	Streptococcus pneumoniae Rx1	49.134	89.689	0.441
clpE	Streptococcus pneumoniae TIGR4	48.819	89.689	0.438
clpC	Bacillus subtilis subsp. subtilis str. 168	43.75	88.136	0.386
clpC	Streptococcus thermophilus LMD-9	43.402	88.842	0.386
clpC	Streptococcus thermophilus LMG 18311	43.243	88.842	0.384
clpC	Streptococcus pneumoniae Rx1	42.765	87.853	0.376
clpC	Streptococcus pneumoniae D39	42.765	87.853	0.376
clpC	Streptococcus pneumoniae TIGR4	42.605	87.853	0.374
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.581	87.571	0.373
clpC	Streptococcus mutans UA159	42.464	87.147	0.37