Detailed information NTG0044672

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: C270_RS05745
• Genome accession: NC_018673
• Coordinates: 1167338..1168429 (-)
• Length: 363 a.a.
• NCBI ID: WP_014974634.1
• Uniprot ID: K0D7V7
• Organism: Leuconostoc carnosum JB16
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1162338..1173429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C270_RS05720 (C270_05550)	-	1162867..1163487 (-)	621	WP_014974629.1	hypothetical protein	-
C270_RS05725 (C270_05555)	-	1163475..1164161 (-)	687	WP_014974630.1	hypothetical protein	-
C270_RS05730 (C270_05560)	-	1164158..1164967 (-)	810	WP_014974631.1	hypothetical protein	-
C270_RS05735 (C270_05565)	-	1164980..1165189 (-)	210	WP_014974632.1	hypothetical protein	-
C270_RS05740 (C270_05570)	-	1165610..1166386 (+)	777	WP_014974633.1	helix-turn-helix transcriptional regulator	-
C270_RS05745 (C270_05575)	sepM	1167338..1168429 (-)	1092	WP_014974634.1	SepM family pheromone-processing serine protease	Regulator
C270_RS05750 (C270_05580)	coaD	1168429..1168905 (-)	477	WP_014974635.1	pantetheine-phosphate adenylyltransferase	-
C270_RS05755 (C270_05585)	rsmD	1168902..1169465 (-)	564	WP_014974636.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
C270_RS05760 (C270_05590)	-	1169565..1169855 (-)	291	WP_014974637.1	YlbG family protein	-
C270_RS05765 (C270_05595)	-	1169852..1171033 (-)	1182	WP_014974638.1	FtsW/RodA/SpoVE family cell cycle protein	-
C270_RS05770 (C270_05600)	pepA	1171040..1172116 (-)	1077	WP_014974639.1	glutamyl aminopeptidase	-
C270_RS05775 (C270_05605)	-	1172154..1172819 (-)	666	WP_014974640.1	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase	-

Sequence

Protein

• Length: 363 a.a.
• Molecular weight: 39232.93 Da
• Isoelectric Point: 10.2117

>NTDB_id=44672 C270_RS05745 WP_014974634.1 1167338..1168429(-) (sepM) [Leuconostoc carnosum JB16]
MRKKSKIIAAIVSLVALIGIIGLVWPLDGYIESPGEADDLARFVTIGGKKDTSKGRYNITSVYLSKANGFGYLRTKISPF
LDYSQSEDVTGGQSSDVFAQVQSFYMQSAIANAEQVAFKKANKPITTQYRGIYVLSVSKQSHFKKSIRVGDTITAVDGHH
YENSDGFIKYLANKGKDVSVTIDYLRNGKKGKATGTTIKLAGSKSPEYPKGRSGIGIVLTDNVAVTTKPKVAVDPGEIGG
PSGGLMFTLQIYDQLTGNKLSKARNISGTGTMNANGYVGEIGGIDKKVIAAKAAGSTVFFAPYLPPNKNILKYEEKHQTN
YQLARDTAKKHAPNIKVVPVVTFQDAINYLETGRIIKTTDKVQ

Nucleotide

• Length: 1092 bp

>NTDB_id=44672 C270_RS05745 WP_014974634.1 1167338..1168429(-) (sepM) [Leuconostoc carnosum JB16]
ATGAGAAAAAAAAGTAAAATTATTGCTGCCATAGTCTCTCTAGTTGCACTTATCGGTATCATAGGACTTGTCTGGCCATT
GGATGGTTATATTGAAAGTCCCGGTGAAGCTGATGATTTGGCTCGGTTTGTGACTATTGGTGGCAAAAAAGATACGTCAA
AAGGTCGTTATAACATTACATCGGTCTATCTTTCTAAAGCCAACGGTTTTGGTTATTTACGAACTAAAATCAGTCCATTC
TTAGATTATTCACAAAGTGAGGACGTGACAGGTGGTCAAAGTTCAGATGTATTTGCTCAAGTACAAAGCTTCTATATGCA
GAGTGCAATTGCTAATGCAGAACAAGTTGCTTTTAAAAAAGCGAACAAGCCAATTACTACACAATACCGCGGAATTTATG
TTTTGAGTGTAAGTAAGCAGTCACATTTTAAGAAATCGATTCGCGTAGGTGATACAATAACTGCAGTTGATGGTCATCAC
TATGAAAATTCTGATGGATTTATTAAGTATTTAGCTAACAAAGGAAAAGATGTTAGTGTTACAATAGATTATTTACGTAA
TGGTAAAAAAGGTAAAGCTACTGGAACGACAATCAAATTGGCTGGTAGTAAGTCGCCGGAATATCCAAAAGGTAGATCTG
GAATTGGTATTGTGTTGACGGATAATGTGGCGGTAACAACAAAACCAAAGGTGGCAGTCGATCCGGGCGAAATTGGCGGT
CCATCAGGTGGTTTAATGTTTACATTACAAATTTATGATCAACTAACTGGCAATAAATTATCAAAAGCACGTAATATTTC
TGGTACCGGAACGATGAATGCCAACGGTTATGTAGGTGAAATTGGTGGTATTGATAAAAAAGTCATAGCCGCCAAGGCAG
CGGGATCAACAGTCTTTTTTGCACCATACTTACCACCAAACAAAAATATATTAAAATATGAAGAAAAGCATCAAACAAAT
TATCAATTAGCACGAGATACAGCTAAGAAACACGCGCCAAATATTAAAGTTGTACCTGTTGTGACGTTCCAAGATGCAAT
TAACTATCTTGAAACGGGTCGTATCATTAAGACAACTGATAAAGTTCAATAA

Domains

Predicted by InterProScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (239-302)

• PDZ domain (PDZ_2) (129-193)

3D structure

• AlphaFold DB: K0D7V7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	38.92	96.97	0.377