Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ST1A_RS08905 Genome accession   NZ_CP065384
Coordinates   1723900..1724193 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain 1A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1718900..1729193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST1A_RS08865 (ST1A_08800) - 1719302..1719745 (-) 444 WP_011681680.1 hypothetical protein -
  ST1A_RS08870 - 1719819..1720157 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  ST1A_RS08875 - 1720201..1720476 (-) 276 WP_011681681.1 hypothetical protein -
  ST1A_RS08880 (ST1A_08810) - 1720488..1720685 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  ST1A_RS08885 (ST1A_08815) - 1720934..1722127 (-) 1194 WP_014608740.1 acetate kinase -
  ST1A_RS08890 (ST1A_08820) comGH 1722183..1723139 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  ST1A_RS08895 (ST1A_08825) comGG 1723184..1723501 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  ST1A_RS08900 (ST1A_08830) comGF 1723479..1723916 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  ST1A_RS08905 (ST1A_08835) comGE 1723900..1724193 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  ST1A_RS08910 (ST1A_08840) comGD 1724165..1724593 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  ST1A_RS08915 (ST1A_08845) comGC 1724553..1724879 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ST1A_RS08920 (ST1A_08850) comGB 1724876..1725976 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  ST1A_RS08925 (ST1A_08855) comGA 1725858..1726799 (-) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  ST1A_RS08930 (ST1A_08860) - 1726880..1727242 (-) 363 WP_023909982.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=446689 ST1A_RS08905 WP_011226625.1 1723900..1724193(-) (comGE) [Streptococcus thermophilus strain 1A]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=446689 ST1A_RS08905 WP_011226625.1 1723900..1724193(-) (comGE) [Streptococcus thermophilus strain 1A]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361